Hai cercato: Biosensis

Codice catalogo: (BSENS-1754-500)

Fornitore: Biosensis

Codice articolo fornitore: S-1754-500

Codice articolo locale: BSENS-1754-500

Descrizione: Sheep serum from non-immunised animals was purified by protein G affinity chromatography. This sheep IgG fraction can be used as negative control antibody for various immunological techniques where sheep primary antibodies are used.

UOM: 1 * 500 µG

Promo

Codice catalogo: (BSENM-1805-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1805-100

Codice articolo locale: BSENM-1805-100

Descrizione: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). Ref: uniprot.org

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENC-1812-50)

Fornitore: Biosensis

Codice articolo fornitore: C-1812-50

Codice articolo locale: BSENC-1812-50

Descrizione: Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells (By similarity). Ref: uniprot.org

UOM: 1 * 50 µl

Promo

Fornitore: Biosensis

Descrizione: Mouse NGF (2.5S) was isolated from mouse submaxillary glands by method of Mobley et al (1976) and is a form of beta-NGF that has identical biological properties. NGF is known to regulate the survival and development of certain sympathetic and sensory neurons. It is a dimer with 2 identical polypeptide chains and dimeric molecular weight of approximately 26,500 Da. Isolation and purification of NGF from mouse submaxillary glands yields preparations of NGF (2.5S) with identical biological activity but with cleavages at the amino terminus (with the loss of 8 amino acids) and/or at the carboxy-terminus (with the loss of arginine). These preparations are named 2.5 NGF.

Certificati

Fornitore: Biosensis

Descrizione: The Biosensis Neurotrophin 4/5 Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the specific, fast and reliable quantification of NT4/5 in less than 4 hours in cell culture supernatants, human citrate-plasma and brain extracts only if used as directed.

Codice catalogo: (BSENG-1784-100)

Fornitore: Biosensis

Codice articolo fornitore: G-1784-100

Codice articolo locale: BSENG-1784-100

Descrizione: Apolipoprotein E (ApoE) is a lipoprotein involved in fat metabolism and acts as cholesterol carrier between cells and across tissues. On a genetic level, three APOE alleles are described, APOE2, APOE3 and APOE4. These alleles give rise to six APOE isoforms, which are differentially implicated in various diseases. In the peripheral system, APOE4 is linked to increased risk of atherosclerosis. In the CNS, the ability of APOE4 in clearing beta-amyloid is impaired, while APOE3 and APOE2 are more efficient in performing this task. The APOE4 genotype in particular has been linked to increased risk for developing Alzheimer's Disease.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1648-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1648-100

Codice articolo locale: BSENM-1648-100

Descrizione: Anti-DCX Mouse T4 Antibody [clone: 30]

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1656-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1656-100

Codice articolo locale: BSENM-1656-100

Descrizione: Anti-UBQL2 Mouse T4 Antibody [clone: 6H9]

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1813-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1813-100

Codice articolo locale: BSENM-1813-100

Descrizione: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Ref: uniprot.org. Antibody is specific for parvalbumin and does not recognize closely related proteins calretinin and calbindin as determined by Western Blotting.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENC-1798-50)

Fornitore: Biosensis

Codice articolo fornitore: C-1798-50

Codice articolo locale: BSENC-1798-50

Descrizione: Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Ref: uniprot.org. Antibody is specific for calbindin and does not recognize closely related proteins parvalbumin and calretinin as determined by Western Blotting.

UOM: 1 * 50 µl

Promo

Codice catalogo: (BSENM-1778-50-B)

Fornitore: Biosensis

Codice articolo fornitore: M-1778-50-B

Codice articolo locale: BSENM-1778-50-B

Descrizione: Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released.

Biosensis' biotinylated proNGF antibody allowing more flexibility in experimental design by using the biotin-avidin/streptavidin detection method. The ability of biotinylated proNGF antibody to detect proNGF has been validated by WB.

UOM: 1 * 50 µG

Promo

Fornitore: Biosensis

Descrizione: The Neurotrophin Antibody Kit contains a collection of sheep antibodies raised against BDNF, NGF, NT3 and NT4/5. The kit is completed with one vial of normal sheep IgG for use as negative control. This kit presents a cost-effective way to investigate neurotrophin protein expression and function by immunological techniques such as immunohistochemistry, ELISA, and inhibition of biological activity.

Codice catalogo: (BSENBEK-2232)

Fornitore: Biosensis

Codice articolo fornitore: BEK-2232

Codice articolo locale: BSENBEK-2232

Descrizione: The Biosensis Multi-Neurotrophin Rapid™ Screening ELISA Kit has been designed to allow rapid screening and quantification of NGF, BDNF, NT3 and NT4/5 in cell culture supernatants, lysates, serum and brain extracts only if used as directed.

UOM: 1 * 192 Tests

Promo

Codice catalogo: (BSENM-1407-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1407-100

Codice articolo locale: BSENM-1407-100

Descrizione: This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. The enzyme also binds to free monoubiquitin and may prevent its degradation in lysosomes (ref: SWISSPROT).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENC-1393-50)

Fornitore: Biosensis

Codice articolo fornitore: C-1393-50

Codice articolo locale: BSENC-1393-50

Descrizione: Neurofilaments are composed of three intermediate filament proteins: light (~68 kDa), medium (~160 kDa) and heavy (~200 kDa), which are involved in the maintenance of the neuronal caliber. Neurofilament medium runs on SDS-PAGE gels in the range 145-170 kDa, with some variation in different species.

UOM: 1 * 50 µl

Promo

Codice catalogo: (BSENM-1378-250)

Fornitore: Biosensis

Codice articolo fornitore: M-1378-250

Codice articolo locale: BSENM-1378-250

Descrizione: Neurofilaments can be defined as the intermediate or 10nm diameter filaments found in neuronal cells. They are composed a mixture of subunits which often includes the neurofilament triplet proteins, NF-L, NF-M and NF-H. Neurofilaments may also include peripherin, alpha-internexin, nestin and in some cases vimentin. Alpha-internexin is a ~66 kDa Class IV intermediate filament subunit expressed in large amounts early in neuronal development, but is downregulated in many neurons as development procedes. Many classes of mature neurons contain alpha-internexin in addition to NF-L, NF-M and NF-H. In some mature neurons alpha-internexin is the only neurofilament subunit expressed. Antibodies to alpha-internexin are therefore unique probes to study and classify neuronal types and follow their processes in sections and in tissue culture. In addition the very early developmental expression of alpha-internexin means its presence is an early and convenient diagnostic feature of neuronal progenitors cells and other cell committed to the neuronal lineage.

UOM: 1 * 250 µl

Promo