Hai cercato: Biosensis

Codice catalogo: (BSENM-1372-250)

Fornitore: Biosensis

Codice articolo fornitore: M-1372-250

Codice articolo locale: BSENM-1372-250

Descrizione: Fibrillarin is part of the small subunit processome complex, involved in the processing of pre-18S ribosomal RNA. Nop1p is the yeast homologue of fibrillarin. Fibrillarin/Nop1p is extraordinarily conserved, so that the yeast and human proteins are 67% identical, and the human protein can functionally replace the yeast protein. This means that suitably cross-reactive antibodies to Nop1p/fibrillarin such as this antibody can be used to reveal nucleoli and study fibrillarin/Nop1p in all eukaryotes and archea tested to date. This antibody is becoming widely used as a convenient marker for nucleoli in a wide variety of species.

UOM: 1 * 250 µl

Promo

Codice catalogo: (BSENM-1576-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1576-100

Codice articolo locale: BSENM-1576-100

Descrizione: SF3B4 is one of 8 subunits of splicing factor SF3B. SF3B4 is ubiquitously expressed in the nuclei of eukaryotic cells, although it migrates into the cytoplasm of dividing cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1653-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1653-100

Codice articolo locale: BSENM-1653-100

Descrizione: Anti-MCHERRY Mouse T4 Antibody [clone: 1C51]

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1311-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1311-100

Codice articolo locale: BSENM-1311-100

Descrizione: The 6X His tag is a short peptide sequence of 6 histidine residues. Epitopes such as the 6X His tag are often included with the target DNA at the time of cloning to produce fusion proteins containing the tag sequence. This allows anti-epitope tag antibodies such as this one to serve as a universal detection reagent for any recombinant protein containing this tag. Anti-epitope antibodies are a useful alternative to generating antibodies to identify a specific recombinant protein. The 6X His motif is often used as a tag on recombinant proteins to facilitate purification with immobilized metal-affinity chromatography.

UOM: 1 * 100 µG

Promo

Fornitore: Biosensis

Descrizione: The Biosensis NGFR/p75^ECD Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the quantification of the extracellular domain (ECD) of human p75 neurotrophin receptor in less than four hours in urine only if used as directed.

Fornitore: Biosensis

Descrizione: The Biosensis GDNF RapidTM enzyme-linked immunosorbent assay (ELISA) Kit is a sandwich ELISA that allows the quantification of GDNF in less than 4 hours in cell culture supernatants, cell lysates, and serum only if used as directed. Please refer to the kit protocol for specific use instructions for each substrate application, in particular rat serum samples.

Fornitore: Biosensis

Descrizione: The oligomeric form of Amyloid Beta peptide (Aβ, 1- 42) has been closely linked to Alzheimer’s Disease. Several ELISAs targeting Aβ have been developed; however, these ELISAs are known to cross-react with Amyloid Beta precursor protein (APP) and are poorly characterised against monomeric and oligomeric forms of the peptide.

Codice catalogo: (BSENC-1398-50)

Fornitore: Biosensis

Codice articolo fornitore: C-1398-50

Codice articolo locale: BSENC-1398-50

Descrizione: The enzyme Peptidylprolyl isomerase (Pin1) is responsible for flipping the proline ring from the cis to trans conformation. This enzyme regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity (ref: SWISSPROT). Pin1 is concentrated in the nucleus in small punctate structures and is particularly obvious in tumor cells.

UOM: 1 * 50 µl

Promo

Fornitore: Biosensis

Descrizione: X63-saporin is an antibody conjugate comprising of the non-specific monoclonal IgG1 antibody X63, chemically conjugated via a reducible disulfide bridge to the ribosome-inactivating protein saporin, purified from saponaria officinalis. Antibody clone X63 has no known binding ability, and thus can be used as negative control antibody. In combination with saporin, X63-saporin is a useful negative control for targeting IgG1-saporin conjugates such as MC192-saporin.

Codice catalogo: (BSENC-1691-100)

Fornitore: Biosensis

Codice articolo fornitore: C-1691-100

Codice articolo locale: BSENC-1691-100

Descrizione: FUNCTION: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. SUBCELLULAR LOCATION: Cytoplasm; cytosol. Cell membrane. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components. ALTERNATIVE PRODUCTS: 8 named isoforms produced by alternative splicing. Additional isoforms seem to exist. Isoforms differ from each other by the presence or absence of up to 5 of the 15 exons. One of these optional exons contains the additional tau/MAP repeat. TISSUE SPECIFICITY: Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. DEVELOPMENTAL STAGE: Four-repeat (type II) tau is expressed in an adult-specific manner and is not found in fetal brain, whereas three-repeat (type I) tau is found in both adult and fetal brain. DOMAIN: The tau/MAP repeat binds to tubulin. In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments and straight filaments, mainly composed of hyperphosphorylated forms of Microtubule-associated protein Tau. Defects in Microtubule-associated protein Tau are a cause of frontotemporal dementia and parkinsonism linked to chromosome 17, as well as a number of other neurodegenerative diseases.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENC-1524-100)

Fornitore: Biosensis

Codice articolo fornitore: C-1524-100

Codice articolo locale: BSENC-1524-100

Descrizione: Adiponectin is synthesized by adipocytes and is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities (ref: SWISSPROT).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENR-078-50)

Fornitore: Biosensis

Codice articolo fornitore: R-078-50

Codice articolo locale: BSENR-078-50

Descrizione: TISSUE SPECIFICITY: Ubiquitously expressed. Expressed in dorsal root ganglia, trigeminal ganglia, spinal chord (Lissauer's tract, dorsal horn and dorsal columns) (at protein level). PTM: N-glycosylated. PTM: Phosphorylated by PKA. SIMILARITY: Belongs to the transient receptor family. TrpV subfamily. SIMILARITY: Contains 3 ANK repeats.

UOM: 1 * 50 µG

Promo

Codice catalogo: (BSENS-1233-100)

Fornitore: Biosensis

Codice articolo fornitore: S-1233-100

Codice articolo locale: BSENS-1233-100

Descrizione: Catenin beta is an adherens junction protein and has a role in the regulation of cell adhesion and in signal transduction through the Wnt pathway. At least 2 isoforms are produced by alternative splicing.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENC-1539-100)

Fornitore: Biosensis

Codice articolo fornitore: C-1539-100

Codice articolo locale: BSENC-1539-100

Descrizione: Peptide YY (PYY) is secreted from endocrine cells in the lower small intestine, colon and pancreas. PYY inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility (Ref: SWISS-Prot).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENC-1536-100)

Fornitore: Biosensis

Codice articolo fornitore: C-1536-100

Codice articolo locale: BSENC-1536-100

Descrizione: Peptide YY (PYY) is secreted from endocrine cells in the lower small intestine, colon and pancreas. PYY inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility (Ref: SWISS-Prot).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENM-1625-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1625-100

Codice articolo locale: BSENM-1625-100

Descrizione: Microtubules are 25nm diameter protein rods found in most kinds of eukaryotic cells. They are polymerized from a dimeric subunit made of one 'a' subunit and one 'b' tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein t (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2 a and MAP2 b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein t (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. Antibodies to MAP2 are therefore excellent markers on neuronal cells, their perikarya and neuronal dendrites.

UOM: 1 * 100 µl

Promo