Hai cercato: Biosensis

Fornitore: Biosensis

Descrizione: Fluoro-Jade stain is a fluorochrome derived from fluorescein, and is commonly used in neuroscience disciplines to label degenerating neurons in ex vivo tissue of the central nervous system.

MSDS

Codice catalogo: (BSENC-1534-500)

Fornitore: Biosensis

Codice articolo fornitore: C-1534-500

Codice articolo locale: BSENC-1534-500

Descrizione: Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).

UOM: 1 * 500 µl

Promo

Codice catalogo: (BSENM-1692-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1692-100

Codice articolo locale: BSENM-1692-100

Descrizione: Anti-HSPB1 Mouse T4 Antibody [clone: 6H11]

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENC-1807-50)

Fornitore: Biosensis

Codice articolo fornitore: C-1807-50

Codice articolo locale: BSENC-1807-50

Descrizione: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). Ref: uniprot.org

UOM: 1 * 50 µl

Promo

Codice catalogo: (BSENR-1838-100)

Fornitore: Biosensis

Codice articolo fornitore: R-1838-100

Codice articolo locale: BSENR-1838-100

Descrizione: The green fluorescent protein (GFP) is a 27 kDa protein isolated originally from the jellyfish Aequoria victoria. It has an endogenous fluorochrome activity with excitation maximum at 395nm and emission maximum at 509 nm, which is similar to that of fluorescein. GFP can be expressed in fluorescent form in essentially any prokaryotic or eukaryotic cell.
This GFP rabbit antibody was made against a recombinant GFP construct originating from an Aequoria species which was engineered to improve spectral properties and prevent oligomerization (1). This form of GFP, referred to as AcGFP, is 94% identical to the eGFP developed by Tsien and co-workers. The antibody can be used to verify the expression, size and stability of both AcGFP and eGFP fusion proteins in western blotting experiments and to amplify GFP signals in tissues of transgenic animals.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1797-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1797-100

Codice articolo locale: BSENM-1797-100

Descrizione: Buffers cytosolic calcium. May stimulate a membrane Ca2+-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Ref: uniprot.org

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1744-50)

Fornitore: Biosensis

Codice articolo fornitore: M-1744-50

Codice articolo locale: BSENM-1744-50

Descrizione: BDNF belongs to the neurotrophin family and promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. It is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease. Microglia release BDNF that may contribute to neuroinflammation and neuropathic pain. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 50 µG

Promo

Fornitore: Biosensis

Descrizione: The Biosensis NGFR/p75ECD Rapid™ enzyme-linked immunosorbent assay (ELISA) kit is a sandwich ELISA that allows the quantification of the extracellular domain (ECD) of mouse p75 neurotrophin receptor in less than 4 hours in cell culture supernatants and urine only if used as directed.

Fornitore: Biosensis

Descrizione: The Biosensis Mouse and Rat proNGF Rapid enzyme-linked immunosorbent assay (ELISA) Kit is a sandwich ELISA that allows the quantification of rodent full-length proNGF protein in less than 4 hours in cell culture supernatants, cell lysates and tissue homogenates only if used as directed. This ELISA Kit has also successfully been used on mouse urine samples (Ryu JC et al., 2018). Please refer to the kit protocol for specific use instructions for each substrate application.

This ELISA kit contains a recombinant mouse proNGF standard expressed in E.coli and consists of a pre-coated anti-proNGF capture antibody, a biotinylated anti-proNGF detection antibody and horseradish peroxidase (HRP)-conjugated streptavidin. The addition of a substrate (3,3',5,5'-tetramethylbenzidine, TMB) yields a colored reaction product which is directly proportional to the concentration of proNGF present in samples and protein standards. A proNGF positive control (QC sample) is provided to assure consistent assay performance. This ELISA kit detects rat proNGF due to high degree of homology (96%) with mouse proNGF based on amino acid sequence, and the ability of this kit in detecting proNGF in rat PC12 cell lysates and rat brain tissue homogenate. In the absence of a true rat proNGF standard, results may be expressed as 'mouse proNGF equivalents'. This ELISA kit shows only 20% reactivity with the human form of proNGF and is therefore not suitable to quantify human proNGF. No cross-reactivity was observed with mature mouse NGF and full-length proBDNF when tested in assay buffer.

The antibodies used in this ELISA kit bind epitopes within the pro-domain (capture) and mature domain (detection) of the protein, thus this ELISA assay does not detect the pro-domain peptide. This kit has not been tested for other applications. Sufficient amount of proNGF standard is supplied to allow for spike- and recovery experiments in order to validate this ELISA assay for other sample matrices if required.

Codice catalogo: (BSENR-102-500)

Fornitore: Biosensis

Codice articolo fornitore: R-102-500

Codice articolo locale: BSENR-102-500

Descrizione: FUNCTION: Target-derived survival factor for peripheral sensory sympathetic neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. SIMILARITY: Belongs to the NGF-beta family.

UOM: 1 * 500 µG

Promo

Codice catalogo: (BSENR-1556-100)

Fornitore: Biosensis

Codice articolo fornitore: R-1556-100

Codice articolo locale: BSENR-1556-100

Descrizione: The elF2c (Argonaute, Ago) protein is a core protein of the RNA-induced silencing complex (RISC).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENR-1500-50)

Fornitore: Biosensis

Codice articolo fornitore: R-1500-50

Codice articolo locale: BSENR-1500-50

Descrizione: The hormone Atrial natriuretic peptide (ANP) is produced by cardiomyocites and is secreted into the bloodstream. ANP acts on convoluted tubules in kidney reducing sodium absorption which results in reducing the blood pressure.

UOM: 1 * 50 µG

Promo

Codice catalogo: (BSENM-1301-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1301-100

Codice articolo locale: BSENM-1301-100

Descrizione: The D-tag system utilises a short hydrophilic peptide (DYKDDDDK) that is fused to either the N- or C-terminus of the protein of interest. It can be used in conjunction with other tags such as the 6X His tag.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1309-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1309-100

Codice articolo locale: BSENM-1309-100

Descrizione: The Human influenza hemagglutin (HA) tag corresponds to a region (98-106 amino acids) from the HA molecule.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1306-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1306-100

Codice articolo locale: BSENM-1306-100

Descrizione: GST (Glutathione S-Transferase) is a 26 kDa protein encoded by the Schistosoma japonicum.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BSENM-1320-100)

Fornitore: Biosensis

Codice articolo fornitore: M-1320-100

Codice articolo locale: BSENM-1320-100

Descrizione: Recognizes native and denatured forms of Green Fluorescent Protein (GFP) and its variants: Enhanced Green Fluorescent Protein (EGFP), Yellow Fluorescent Protein (YFP), Enhanced Yellow Fluorescent Protein (EYFP) and Cyan Fluorescent Protein (CFP).

UOM: 1 * 100 µG

Promo