Hai cercato: genome

Codice catalogo: (BOSSBS-3780R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-3780R-A350

Codice articolo locale: BOSSBS-3780R-A350

Descrizione: This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5974R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-5974R-A555

Codice articolo locale: BOSSBS-5974R-A555

Descrizione: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5974R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-5974R-A680

Codice articolo locale: BOSSBS-5974R-A680

Descrizione: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3780R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-3780R-A647

Codice articolo locale: BOSSBS-3780R-A647

Descrizione: This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains.

UOM: 1 * 100 µl

Promo

Codice catalogo: (732-3498)

Fornitore: VWR Collection

Codice articolo locale: VWRI732-3498

Descrizione: Iso-freeze PCR racks are specially designed for Qiagen® and Corbett Rotor-Gene® tubes.

UOM: 1 * 2 pezzi

Promo

Codice catalogo: (BOSSBS-10266R)

Fornitore: Bioss

Codice articolo fornitore: BS-10266R

Codice articolo locale: BOSSBS-10266R

Descrizione: Tbx3 gene is a member of a phylogenetically conserved family of genes that share a common DNA binding domain, the T box. T box genes encode transcription factors involved in the regulation of developmental processes. Tbx3 is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8498R)

Fornitore: Bioss

Codice articolo fornitore: BS-8498R

Codice articolo locale: BOSSBS-8498R

Descrizione: REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15419R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-15419R-A488

Codice articolo locale: BOSSBS-15419R-A488

Descrizione: Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - seta - pseudoseta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15419R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-15419R-FITC

Codice articolo locale: BOSSBS-15419R-FITC

Descrizione: Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - seta - pseudoseta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15419R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-15419R-A680

Codice articolo locale: BOSSBS-15419R-A680

Descrizione: Theta-globin mRNA is found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. The theta-1 gene may be expressed very early in embryonic life, perhaps sometime before 5 weeks. Theta-1 is a member of the human alpha-globin gene cluster that involves five functional genes and two pseudogenes. The order of genes is: 5' - seta - pseudoseta - mu - pseudoalpha-2 -pseudoalpha-1 - alpha-2 - alpha-1 - theta-1 - 3'. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8498R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-8498R-A555

Codice articolo locale: BOSSBS-8498R-A555

Descrizione: REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8498R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-8498R-FITC

Codice articolo locale: BOSSBS-8498R-FITC

Descrizione: REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6147R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-6147R-CY3

Codice articolo locale: BOSSBS-6147R-CY3

Descrizione: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6142R)

Fornitore: Bioss

Codice articolo fornitore: BS-6142R

Codice articolo locale: BOSSBS-6142R

Descrizione: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3322R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-3322R-A680

Codice articolo locale: BOSSBS-3322R-A680

Descrizione: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukaemia gene, results in chronic myeloproliferative disorder with eosinophilia.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12245R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-12245R-FITC

Codice articolo locale: BOSSBS-12245R-FITC

Descrizione: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].

UOM: 1 * 100 µl

Promo