Hai cercato: genome

Codice catalogo: (BOSSBS-1342R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-1342R-CY5

Codice articolo locale: BOSSBS-1342R-CY5

Descrizione: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-7619R)

Fornitore: Bioss

Codice articolo fornitore: BS-7619R

Codice articolo locale: BOSSBS-7619R

Descrizione: This gene encodes a proline rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53 mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6928R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-6928R-CY5.5

Codice articolo locale: BOSSBS-6928R-CY5.5

Descrizione: CCDC17, also known as FLJ17921 or RP4-697E16.4, is a 622 amino acid protein expressed as four isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-2443R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-2443R-FITC

Codice articolo locale: BOSSBS-2443R-FITC

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

UOM: 1 * 100 µl

Promo

Codice catalogo: (USBIM3886-75A-HRP)

Fornitore: US Biological

Codice articolo fornitore: M3886-75A-HRP

Codice articolo locale: USBIM3886-75A-HRP

Descrizione: Anti-MHC Class 1 Chain-related Gene A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

UOM: 1 * 200 µl

Promo

Codice catalogo: (MLDVR8361)

Fornitore: Molecular Devices

Codice articolo fornitore: R8361

Codice articolo locale: MLDVR8361

Descrizione: SpectraMax® DuoLuc™ reporter assay kit offers sensitive detection of dual luciferase reporter gene assays, which are important tools for monitoring gene expression and other cellular events.

UOM: 1 * 1 KIT

Promo

Codice catalogo: (BOSSBS-7914R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-7914R-A680

Codice articolo locale: BOSSBS-7914R-A680

Descrizione: The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6147R)

Fornitore: Bioss

Codice articolo fornitore: BS-6147R

Codice articolo locale: BOSSBS-6147R

Descrizione: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb 2011].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9165R)

Fornitore: Bioss

Codice articolo fornitore: BS-9165R

Codice articolo locale: BOSSBS-9165R

Descrizione: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-20473R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-20473R-A680

Codice articolo locale: BOSSBS-20473R-A680

Descrizione: This gene encodes a member of the immunoglobulin superfamily. The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6. A pseudogene of this gene has been identified in this cluster. The encoded protein is an integral plasma membrane protein involved in lipid, fatty-acid, and sterol metabolism. Alterations in this gene may be associated with several disease states including metabolic syndrome. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15526R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-15526R-A647

Codice articolo locale: BOSSBS-15526R-A647

Descrizione: This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15585R)

Fornitore: Bioss

Codice articolo fornitore: BS-15585R

Codice articolo locale: BOSSBS-15585R

Descrizione: AFM is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5937R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-5937R-CY3

Codice articolo locale: BOSSBS-5937R-CY3

Descrizione: This gene encodes a mitochondrial outer membrane protein. It has a potential role in tumorigenesis, which may result from negative regulation of the p53 tumor suppressor gene. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Aug 2011].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11356R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-11356R-A750

Codice articolo locale: BOSSBS-11356R-A750

Descrizione: The protein encoded by this gene is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. This gene also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7. Multiple transcript variants encoding different isoforms have been described for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8021R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-8021R-A647

Codice articolo locale: BOSSBS-8021R-A647

Descrizione: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8021R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-8021R-A488

Codice articolo locale: BOSSBS-8021R-A488

Descrizione: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo