Hai cercato: genome

Codice catalogo: (BOSSBS-7696R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-7696R-A647

Codice articolo locale: BOSSBS-7696R-A647

Descrizione: This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-10385R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-10385R-A350

Codice articolo locale: BOSSBS-10385R-A350

Descrizione: Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6338R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-6338R-A488

Codice articolo locale: BOSSBS-6338R-A488

Descrizione: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6338R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-6338R-FITC

Codice articolo locale: BOSSBS-6338R-FITC

Descrizione: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6089R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-6089R-CY5

Codice articolo locale: BOSSBS-6089R-CY5

Descrizione: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3309R)

Fornitore: Bioss

Codice articolo fornitore: BS-3309R

Codice articolo locale: BOSSBS-3309R

Descrizione: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3308R)

Fornitore: Bioss

Codice articolo fornitore: BS-3308R

Codice articolo locale: BOSSBS-3308R

Descrizione: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8021R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-8021R-CY5

Codice articolo locale: BOSSBS-8021R-CY5

Descrizione: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants containing different 5' UTRs, but encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9266R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-9266R-CY5.5

Codice articolo locale: BOSSBS-9266R-CY5.5

Descrizione: This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9266R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-9266R-A750

Codice articolo locale: BOSSBS-9266R-A750

Descrizione: This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterised.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9473R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-9473R-HRP

Codice articolo locale: BOSSBS-9473R-HRP

Descrizione: The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9473R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-9473R-FITC

Codice articolo locale: BOSSBS-9473R-FITC

Descrizione: The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6905R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-6905R-A350

Codice articolo locale: BOSSBS-6905R-A350

Descrizione: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-7914R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-7914R-CY5.5

Codice articolo locale: BOSSBS-7914R-CY5.5

Descrizione: The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1417R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-1417R-CY7

Codice articolo locale: BOSSBS-1417R-CY7

Descrizione: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5592R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-5592R-CY7

Codice articolo locale: BOSSBS-5592R-CY7

Descrizione: This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq].

UOM: 1 * 100 µl

Promo