Hai cercato: u200d

Codice catalogo: (GLSNF2070452)

Fornitore: GILSON

Codice articolo fornitore: F2070452

Codice articolo locale: GLSNF2070452

Descrizione: [EN]PUSHBUTTON ASSEMBLY U100 1 * 1 pezzi

UOM: 1 * 1 pezzi

Promo

Codice catalogo: (J63219.ME)

Fornitore: Thermo Scientific

Codice articolo fornitore: J63219.ME

Codice articolo locale: ALFAJ63219.ME

Descrizione: Urapidil hydrochloride ≥98%

UOM: 1 * 500 mg

MSDS Certificati Promo

Codice catalogo: (30-0451-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-0451-U100

Codice articolo locale: TNBO30-0451-U100

Descrizione: The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.

UOM: 1 * 100 µG

Promo

Codice catalogo: (30-5887-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-5887-U100

Codice articolo locale: TNBO30-5887-U100

Descrizione: The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin alpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.

UOM: 1 * 100 µG

Promo

Codice catalogo: (50-5887-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 50-5887-U100

Codice articolo locale: TNBO50-5887-U100

Descrizione: The DATK32 antibody is specific for a combinatorial epitope of the mouse integrin alpha 4/beta 7 (LPAM-1) heterodimer. LPAM-1 is expressed on most mature lymphocytes and sub-populations of thymocytes and bone marrow cells. It is involved in lymphocyte adhesion and migration and is a receptor for several extracellular matrix proteins including VCAM-1, fibronectin, and MAdCAM-1.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-1529-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-1529-U100

Codice articolo locale: TNBO70-1529-U100

Descrizione: The BNI3 antibody is specific for human CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-9919-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-9919-U100

Codice articolo locale: TNBO70-9919-U100

Descrizione: The NOK-1 antibody reacts with human CD178 (Fas ligand) in both membrane bound and soluble forms. Fas ligand is a 40 kDa transmembrane glycoprotein, a member of the TNF family, and is expressed by activated T and NK cells, neutrophils, and monocytes. Interactions between CD178 (Fas ligand) and CD95 (Fas) induce a program of apoptosis and play a key role in immune regulation and homeostasis. The extracellular domain of human CD178 can be cleaved from the surface by matrix metalloproteinases (MMPs) resulting in a 26 kDa soluble protein.

UOM: 1 * 100 µG

Promo

Codice catalogo: (75-1886-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 75-1886-U100

Codice articolo locale: TNBO75-1886-U100

Descrizione: The 2.43 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation induced by binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck and facilitate intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death in tumor cells, as well as in cells infected by virus, bacteria or parasites.

UOM: 1 * 100 µG

Promo

Codice catalogo: (35-0621-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 35-0621-U100

Codice articolo locale: TNBO35-0621-U100

Descrizione: The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-0089-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-0089-U100

Codice articolo locale: TNBO70-0089-U100

Descrizione: The Hit8a antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

UOM: 1 * 100 µG

Promo

Codice catalogo: (30-0457-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-0457-U100

Codice articolo locale: TNBO30-0457-U100

Descrizione: The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB.

UOM: 1 * 100 µG

Promo

Codice catalogo: (30-0112-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-0112-U100

Codice articolo locale: TNBO30-0112-U100

Descrizione: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-5921-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-5921-U100

Codice articolo locale: TNBO70-5921-U100

Descrizione: The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.

UOM: 1 * 100 µG

Promo

Codice catalogo: (30-7311-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-7311-U100

Codice articolo locale: TNBO30-7311-U100

Descrizione: The XMG1.2 antibody is specific for mouse Interferon-gamma (IFN-g), a 20 kDa type II cytokine known for its central roles in protection against bacterial or viral pathogens and for its anti-tumor properties. IFN-g is secreted by several types of immune cells which allow the cytokine to modulate innate immunity when secreted by NK and NKT cells, and to function in support of adaptive immunity when secreted by Th1 and CD8+ T cells (CTLs).

UOM: 1 * 100 µG

Promo

Codice catalogo: (20-7311-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 20-7311-U100

Codice articolo locale: TNBO20-7311-U100

Descrizione: The XMG1.2 antibody is specific for mouse Interferon-gamma (IFN-g), a 20 kDa type II cytokine known for its central roles in protection against bacterial or viral pathogens and for its anti-tumor properties. IFN-g is secreted by several types of immune cells, which allow the cytokine to modulate innate immunity, when secreted by NK and NKT cells, and to function in supporting adaptive immunity when secreted by Th1 and CD8+ T cells (CTLs).

UOM: 1 * 100 µG

Promo

Codice catalogo: (50-5941-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 50-5941-U100

Codice articolo locale: TNBO50-5941-U100

Descrizione: The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).

UOM: 1 * 100 µG

Promo