Hai cercato: u200b

Codice catalogo: (GLSNF2070452)

Fornitore: GILSON

Codice articolo fornitore: F2070452

Codice articolo locale: GLSNF2070452

Descrizione: [EN]PUSHBUTTON ASSEMBLY U100 1 * 1 pezzi

UOM: 1 * 1 pezzi

Promo

Codice catalogo: (J63219.ME)

Fornitore: Thermo Scientific

Codice articolo fornitore: J63219.ME

Codice articolo locale: ALFAJ63219.ME

Descrizione: Urapidil hydrochloride ≥98%

UOM: 1 * 500 mg

MSDS Certificati Promo

Codice catalogo: (20-0081-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 20-0081-U100

Codice articolo locale: TNBO20-0081-U100

Descrizione: The 53-6.7 antibody reacts with the 32-34 kDa alpha subunit of mouse CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor in antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

UOM: 1 * 100 µG

Promo

Codice catalogo: (40-0112-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 40-0112-U100

Codice articolo locale: TNBO40-0112-U100

Descrizione: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165 to 170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (80-0112-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 80-0112-U100

Codice articolo locale: TNBO80-0112-U100

Descrizione: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (75-0453-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 75-0453-U100

Codice articolo locale: TNBO75-0453-U100

Descrizione: The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.

UOM: 1 * 100 µG

Promo

Codice catalogo: (30-0452-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 30-0452-U100

Codice articolo locale: TNBO30-0452-U100

Descrizione: The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-0441-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-0441-U100

Codice articolo locale: TNBO70-0441-U100

Descrizione: The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-4732-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-4732-U100

Codice articolo locale: TNBO70-4732-U100

Descrizione: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

UOM: 1 * 100 µG

Promo

Codice catalogo: (65-0251-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 65-0251-U100

Codice articolo locale: TNBO65-0251-U100

Descrizione: The PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (20-0621-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 20-0621-U100

Codice articolo locale: TNBO20-0621-U100

Descrizione: The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-0452-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-0452-U100

Codice articolo locale: TNBO70-0452-U100

Descrizione: The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.

UOM: 1 * 100 µG

Promo

Codice catalogo: (75-4732-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 75-4732-U100

Codice articolo locale: TNBO75-4732-U100

Descrizione: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-0037-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-0037-U100

Codice articolo locale: TNBO70-0037-U100

Descrizione: The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (40-5874-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 40-5874-U100

Codice articolo locale: TNBO40-5874-U100

Descrizione: The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.

UOM: 1 * 100 µG

Promo

Codice catalogo: (80-0454-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 80-0454-U100

Codice articolo locale: TNBO80-0454-U100

Descrizione: The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors.

UOM: 1 * 100 µG

Promo