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Codice catalogo: (70-1522-U100)
Fornitore: Tonbo Biosciences
Codice articolo fornitore: 70-1522-U100
Codice articolo locale: TNBO70-1522-U100
Descrizione: Anti-CTLA4 Armenian Hamster Monoclonal Antibody [clone: UC10-4F10-11]
UOM: 1 * 100 µG


Codice catalogo: (40-1522-U100)
Fornitore: Tonbo Biosciences
Codice articolo fornitore: 40-1522-U100
Codice articolo locale: TNBO40-1522-U100
Descrizione: The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.
UOM: 1 * 100 µG


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Fornitore: Tonbo Biosciences
Descrizione: The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.

Fornitore: Tonbo Biosciences
Descrizione: The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.

Fornitore: Tonbo Biosciences
Descrizione: The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.

Codice catalogo: (USBIC2548-83A3)
Fornitore: US Biological
Codice articolo fornitore: C2548-83A3
Codice articolo locale: USBIC2548-83A3
Descrizione: Anti-CTLA4 Hamster Monoclonal Antibody [clone: UC10-4B9]
UOM: 1 * 500 µG


Codice catalogo: (PRSI76-850)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-850
Codice articolo locale: PRSI76-850
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,1 mg

New Product


Codice catalogo: (PRSI76-852)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-852
Codice articolo locale: PRSI76-852
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,025 mg

New Product


Codice catalogo: (PRSI76-853)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-853
Codice articolo locale: PRSI76-853
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,1 mg

New Product


Codice catalogo: (PRSI76-849)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-849
Codice articolo locale: PRSI76-849
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,1 mg

New Product


Codice catalogo: (PRSI76-851)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-851
Codice articolo locale: PRSI76-851
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,1 mg

New Product


Codice catalogo: (PRSI76-855)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-855
Codice articolo locale: PRSI76-855
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,1 mg

New Product


Codice catalogo: (PRSI76-856)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-856
Codice articolo locale: PRSI76-856
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,025 mg

New Product


Codice catalogo: (PRSI76-854)
Fornitore: ProSci Inc.
Codice articolo fornitore: 76-854
Codice articolo locale: PRSI76-854
Descrizione: The UC10-4F10-11 monoclonal antibody specifically reacts with the mouse Cytotoxic T-Lymphocyte Antigen-4 (CTLA-4), also known as CD152. It is a protein with a structure similar to CD28 regarding the genomic organization, amino acid sequence, and structure. CTLA-4 is expressed on activated T cells and CD25+/CD4+ Treg lymphocytes and binds the members of the B7 family, B7-1 (CD80) and B7-2 (CD86), with higher affinity than CD28. CD28 seems to provide opposing signal to T lymphocytes, while CD152 inhibits the T lymphocytes progression to an activated state and their proliferation, CD28 is a costimulator. The mouse UC10 -4F10-11 monoclonal antibody does not cross-react with the rat leukocytes.
UOM: 1 * 0,025 mg

New Product


Codice catalogo: (ABCAAB210383-100)
Fornitore: Abcam
Codice articolo fornitore: AB210383-100
Codice articolo locale: ABCAAB210383-100
Descrizione: CTLA4 ANTIBODY [UC10-4F10-11] (PHYCOERYT 1 * 100 G
UOM: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

Codice catalogo: (ABCAAB210384-100)
Fornitore: Abcam
Codice articolo fornitore: AB210384-100
Codice articolo locale: ABCAAB210384-100
Descrizione: CTLA4 ANTIBODY [UC10-4F10-11] (PE/CY7 ) 1 * 100 G
UOM: 1 * 100 µG

Market Source Item This is a MarketSource item. Additional charges may apply

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