Hai cercato: u0001

Codice catalogo: (GLSNF2070452)

Fornitore: GILSON

Codice articolo fornitore: F2070452

Codice articolo locale: GLSNF2070452

Descrizione: [EN]PUSHBUTTON ASSEMBLY U100 1 * 1 pezzi

UOM: 1 * 1 pezzi

Promo

Codice catalogo: (J63219.ME)

Fornitore: Thermo Scientific

Codice articolo fornitore: J63219.ME

Codice articolo locale: ALFAJ63219.ME

Descrizione: Urapidil hydrochloride ≥98%

UOM: 1 * 500 mg

MSDS Certificati Promo

Codice catalogo: (70-0452-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-0452-U100

Codice articolo locale: TNBO70-0452-U100

Descrizione: The RA3-6B2 antibody reacts with the human and mouse CD45 isoform known as CD45R, or B220, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns, all critical for leukocyte function. In mouse, the CD45R/B220 isoform is predominantly found on B cells, at varying levels on all stages from pro-B cells to activated B cells, and may also be detected on certain T cell and NK cell subsets. It is of note that B220 is not similarly expressed on human B cells, where it appears to be differentiation-specific and therefore expressed on only some B cell subsets. Other forms of CD45 with restricted cellular expression include CD45RA, CD45RB and CD45RO.

UOM: 1 * 100 µG

Promo

Codice catalogo: (75-4732-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 75-4732-U100

Codice articolo locale: TNBO75-4732-U100

Descrizione: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

UOM: 1 * 100 µG

Promo

Codice catalogo: (40-0041-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 40-0041-U100

Codice articolo locale: TNBO40-0041-U100

Descrizione: The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-7041-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-7041-U100

Codice articolo locale: TNBO70-7041-U100

Descrizione: The 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).

UOM: 1 * 100 µG

Promo

Codice catalogo: (40-5874-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 40-5874-U100

Codice articolo locale: TNBO40-5874-U100

Descrizione: The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is expressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.

UOM: 1 * 100 µG

Promo

Codice catalogo: (80-4724-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 80-4724-U100

Codice articolo locale: TNBO80-4724-U100

Descrizione: The C1.18.4 immunoglobulin is useful as an isotype-matched control. The C.1.18.4 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2a antibodies.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-0037-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-0037-U100

Codice articolo locale: TNBO70-0037-U100

Descrizione: The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (60-4031-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 60-4031-U100

Codice articolo locale: TNBO60-4031-U100

Descrizione: The LTF-2 immunoglobulin is useful as an isotype-matched control. The LTF-2 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2b antibodies.

UOM: 1 * 100 µG

Promo

Codice catalogo: (40-1522-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 40-1522-U100

Codice articolo locale: TNBO40-1522-U100

Descrizione: The UC10-4F10-11 antibody is specific for mouse CD152, commonly known as CTLA-4, a 33-37 kDa protein expressed as a homodimer on the surface of activated T and B cells, and on thymocytes. CTLA-4 is structurally similar, yet functionally disparate, to the T cell co-stimulatory molecule CD28. Both CTLA-4 and CD28 interact with the co-stimulatory molecules CD80 (B7-1) and CD86 (B7-2) on antigen-presenting cells, with CTLA-4 displaying a higher avidity than CD28. While CD28 typically delivers a potent co-stimulatory signal in support of T cell activation, CTLA-4 appears to act as a negative regulator of T cell activation and may contribute to the suppressor function of Treg cells.

UOM: 1 * 100 µG

Promo

Codice catalogo: (55-4321-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 55-4321-U100

Codice articolo locale: TNBO55-4321-U100

Descrizione: The 2A3 immunoglobulin is useful as an isotype-matched control. The 2A3 immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG2a antibodies.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-4321-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-4321-U100

Codice articolo locale: TNBO70-4321-U100

Descrizione: Purified Rat IgG2a Isotype Control (2A3)

UOM: 1 * 100 µG

Promo

Codice catalogo: (50-5773-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 50-5773-U100

Codice articolo locale: TNBO50-5773-U100

Descrizione: The 3G3 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is expressed at constitutively high levels in Treg cells, which are further identified as being CD4+ CD25+. In resting conventional T cells (CD4+ CD25-) Foxp3 expression is restricted, and upon TCR activation is expressed only transiently and in a small proportion of cells. However, the growth factor TGF-beta has been shown to induce expression of Foxp3 in naïve T cells, driving their development into Foxp3+ Tregs, which are called “induced” or “adaptive” Tregs. These cells are phenotypically similar to so-called “natural” Tregs (CD4+ CD25high Foxp3+) which originate in the thymus and comprise the majority of Treg cells. Tregs are critical for maintaining peripheral tolerance and are implicated in the development of autoimmunity.

UOM: 1 * 100 µG

Promo

Codice catalogo: (75-0903-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 75-0903-U100

Codice articolo locale: TNBO75-0903-U100

Descrizione: The 30-H12 antibody reacts with mouse CD90.2 (Thy1.2). CD90.2 is a strain-specific allelic form of the GPI-linked membrane associated protein CD90 and is involved in adhesion and signal transduction. CD90.2 is expressed on thymocytes, mature T cells and neurons in mouse strains that express the CD90.2 allele (BALB/c, CBA, C3H, C57BL/6, SJL and others). 30-H12 does not react with the CD90.1 allele expressed in mouse strains such as PL and AKR.

UOM: 1 * 100 µG

Promo

Codice catalogo: (70-4732-U100)

Fornitore: Tonbo Biosciences

Codice articolo fornitore: 70-4732-U100

Codice articolo locale: TNBO70-4732-U100

Descrizione: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

UOM: 1 * 100 µG

Promo