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Codice catalogo: (BOSSBS-13454R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-13454R-A488
Codice articolo locale: BOSSBS-13454R-A488
Descrizione: GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13487R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-13487R-A750
Codice articolo locale: BOSSBS-13487R-A750
Descrizione: Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjren's syndrome and Hepatitis B.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13487R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-13487R-CY5
Codice articolo locale: BOSSBS-13487R-CY5
Descrizione: Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjé°ƒren's syndrome and Hepatitis B.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13487R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-13487R-A647
Codice articolo locale: BOSSBS-13487R-A647
Descrizione: Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjé°ƒren's syndrome and Hepatitis B.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11687R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11687R-A750
Codice articolo locale: BOSSBS-11687R-A750
Descrizione: PCSK1N is a 260 amino acid protein that is both secreted and localised to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
UOM: 1 * 100 µl


Codice catalogo: (EHERC16972000)
Fornitore: EHRENSTORFER
Codice articolo fornitore: C16972000
Codice articolo locale: EHERC16972000
Descrizione: Potassio sorbato
UOM: 1 * 0,25 g


Fornitore: MERCK PRODUCTION CHEMICALS
Descrizione: Acido sorbico, EMPROVE® ESSENTIAL FCC, BP, Ph. Eur., E200, NF suitable for use as excipient, SAFC®
Codice catalogo: (BOSSBS-11687R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-11687R-CY5
Codice articolo locale: BOSSBS-11687R-CY5
Descrizione: PCSK1N is a 260 amino acid protein that is both secreted and localized to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11687R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-11687R-HRP
Codice articolo locale: BOSSBS-11687R-HRP
Descrizione: PCSK1N is a 260 amino acid protein that is both secreted and localized to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13487R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13487R-CY3
Codice articolo locale: BOSSBS-13487R-CY3
Descrizione: Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. against golgin 245 are associated with two chronic disorders known as Sjé°ƒren's syndrome and Hepatitis B.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7736R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-7736R-CY7
Codice articolo locale: BOSSBS-7736R-CY7
Descrizione: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
UOM: 1 * 100 µl


Codice catalogo: (1.05118.9025)
Fornitore: MERCK PRODUCTION CHEMICALS
Codice articolo fornitore: 1.05118.9025
Codice articolo locale: MERP1.05118.9025
Descrizione: Potassio sorbato 99.0-101.0% (by acidimetry), EMPROVE® ESSENTIAL FCC, BP, E202, Ph. Eur., NF suitable for use as excipient, SAFC®
UOM: 1 * 25 kg

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Codice catalogo: (ICNA0210293780)
Fornitore: MP Biomedicals
Codice articolo fornitore: 0210293780
Codice articolo locale: ICNA0210293780
Descrizione: Sorbic acid (2,4-hexadienoic acid) is a straight chain unsaturated fatty acid. It is an antimicrobial agent. The antimicrobial action of sorbic acid is due to its inhibitory influence on various enzymes in the microbial cell such as enzymes involved in carbohydrate metabolism such as enolase and lactate dehydrogenase, enzymes of citric acid cycles.
UOM: 1 * 100 g

Certificati


Codice catalogo: (BOSSBS-13345R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-13345R-A750
Codice articolo locale: BOSSBS-13345R-A750
Descrizione: The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7736R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-7736R-CY5
Codice articolo locale: BOSSBS-7736R-CY5
Descrizione: Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the elongin B and C complex. Serveral other families of proteins also contain SOCS boxes but differ from the SOCS proteins in the type of domain they contained upstream of the SOCS box. Four members of the ankyrin repeat and SOCS box-containing (ASB) protein family are identified and termed as ASB-1, ASB-2, ASB-3 and ASB-4. ASB-1 is expressed in multiple organs, including the hematopoietic compartment. ASB-1 knock-out mice display a diminution of spermatogenesis with less complete filling of seminiferous tubules. Asb-2 is a novel retinoic-acid (RA)-induced gene in acute promyelocytic leukemia (APL) cells and its expression induces growth-inhibition and chromatin condensation recapitulating early events critical to RA-induced differentiaiton of APL cells. ASB-2 is directly induced by all-trans retinotic acid, by the binding of RARa to the RAR binding element/RXR binding element in the Asb-2 promoter.
UOM: 1 * 100 µl


Fornitore: MERCK PRODUCTION CHEMICALS
Descrizione: Acido fumarico NF, SAFC®
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