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Codice catalogo: (BOSSBS-0385R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-0385R-A647
Codice articolo locale: BOSSBS-0385R-A647
Descrizione: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4142R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-4142R-HRP
Codice articolo locale: BOSSBS-4142R-HRP
Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
UOM: 1 * 100 µl


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Codice catalogo: (BOSSBS-4142R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-4142R-A680
Codice articolo locale: BOSSBS-4142R-A680
Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0076M-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-0076M-CY5.5
Codice articolo locale: BOSSBS-0076M-CY5.5
Descrizione: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13038R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-13038R-A750
Codice articolo locale: BOSSBS-13038R-A750
Descrizione: Dynamin I is a GTPase enzyme required for the retrieval of synaptic vesicles after exocytosis and functions in endocytosis by stimulating assembly of invaginating synaptic vesicles (1). Dynamin I is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C (PKC) (25). The phosphorylation site in PKC-phosphorylated Dynamin I is a single site at Serine 795, which is located near a binding site for the SH3 domain of p85, the regulatory subunit of phosphatidylinositol 3-kinase (25). Dephosphorylation is required for synaptic vesicle retrieval, suggesting that phosphorylation affects the subcellular localization of Dynamin I (5). Mouse, rat and human Dynamin I are phosphorylated on serine residues, including Ser 778, by Cdk5, regulating PACSIN1 recruitment and enabling synaptic vesicle endocytosis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13038R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-13038R-CY5
Codice articolo locale: BOSSBS-13038R-CY5
Descrizione: Dynamin I is a GTPase enzyme required for the retrieval of synaptic vesicles after exocytosis and functions in endocytosis by stimulating assembly of invaginating synaptic vesicles (1). Dynamin I is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C (PKC) (2–5). The phosphorylation site in PKC-phosphorylated Dynamin I is a single site at Serine 795, which is located near a binding site for the SH3 domain of p85, the regulatory subunit of phosphatidylinositol 3-kinase (2–5). Dephosphorylation is required for synaptic vesicle retrieval, suggesting that phosphorylation affects the subcellular localization of Dynamin I (5). Mouse, rat and human Dynamin I are phosphorylated on serine residues, including Ser 778, by Cdk5, regulating PACSIN1 recruitment and enabling synaptic vesicle endocytosis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0076M-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-0076M-A555
Codice articolo locale: BOSSBS-0076M-A555
Descrizione: Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0385R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-0385R-CY5
Codice articolo locale: BOSSBS-0385R-CY5
Descrizione: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0385R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-0385R-A488
Codice articolo locale: BOSSBS-0385R-A488
Descrizione: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4142R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-4142R-CY5.5
Codice articolo locale: BOSSBS-4142R-CY5.5
Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0385R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-0385R-A750
Codice articolo locale: BOSSBS-0385R-A750
Descrizione: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fibre dynamics and cell migration.
UOM: 1 * 100 µl


Codice catalogo: (USBIS9111-04)
Fornitore: US Biological
Codice articolo fornitore: S9111-04
Codice articolo locale: USBIS9111-04
Descrizione: Anti-Synaptic adhesion-like molecule 2 Sheep Polyclonal Antibody
UOM: 1 * 100 µG


Codice catalogo: (BOSSBS-4142R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-4142R-A750
Codice articolo locale: BOSSBS-4142R-A750
Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4142R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-4142R-CY7
Codice articolo locale: BOSSBS-4142R-CY7
Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4142R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-4142R-CY3
Codice articolo locale: BOSSBS-4142R-CY3
Descrizione: May be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11198R)
Fornitore: Bioss
Codice articolo fornitore: BS-11198R
Codice articolo locale: BOSSBS-11198R
Descrizione: The ProSAP family of proteins contain many protein-protein interaction domains and serve as scaffolding mediators within the post-synaptic density (PSD) of excitatory brain synapses. The PSD is an electron-dense structure underneath the post-synaptic plasma membrane of excitatory synapses that anchors and clusters glutamate receptors opposite to the pre-synaptic neurotransmitter release site. Shank proteins contain PDZ modular domains that coordinate the synaptic localization of ion channels, receptors, signaling enzymes, and cell adhesion molecules. The PDZ domain mediates protein-protein interactions via the recognition of a conserved sequence motif at the C-terminus of their target protein(s). ProSAPiP1 (proline rich synapse associated protein interacting protein 1) is a 673 amino acid protein that interacts with the PDZ domain of Shank 3. ProSAPiP1 expression is brain-specific with highest expression within the cerebellum, hippocampus and cerebral cortex.
UOM: 1 * 100 µl


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