Hai cercato: giant

Codice catalogo: (609-0231)

Fornitore: VWR Collection

Codice articolo locale: VWRI609-0231

Descrizione: View giant size digits on this bench timer from across the lab. Visible from shelves, in hoods, or perched on instruments. Eliminates 'squinting' to observe alarm time remaining.

UOM: 1 * 1 pezzi

Promo

Codice catalogo: (USBIL2651-75C)

Fornitore: US Biological

Codice articolo fornitore: L2651-75C

Codice articolo locale: USBIL2651-75C

Descrizione: Anti-LLGL2 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Promo

Codice catalogo: (BOSSBS-4771R)

Fornitore: Bioss

Codice articolo fornitore: BS-4771R

Codice articolo locale: BOSSBS-4771R

Descrizione: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R-FITC

Codice articolo locale: BOSSBS-11025R-FITC

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9094R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-9094R-A555

Codice articolo locale: BOSSBS-9094R-A555

Descrizione: AHNAK2 contains 1 PDZ (DHR) domain. There are 3 named isoforms of AHNAK2 produced by alternative splicing. AHNAK2 is a 600-kDa protein composed of a large number of highly conserved repeat segments. AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R

Codice articolo locale: BOSSBS-11025R

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9094R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-9094R-CY5

Codice articolo locale: BOSSBS-9094R-CY5

Descrizione: AHNAK2 contains 1 PDZ (DHR) domain. There are 3 named isoforms of AHNAK2 produced by alternative splicing. AHNAK2 is a 600-kDa protein composed of a large number of highly conserved repeat segments. AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9094R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-9094R-CY3

Codice articolo locale: BOSSBS-9094R-CY3

Descrizione: AHNAK2 contains 1 PDZ (DHR) domain. There are 3 named isoforms of AHNAK2 produced by alternative splicing. AHNAK2 is a 600-kDa protein composed of a large number of highly conserved repeat segments. AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9094R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-9094R-CY7

Codice articolo locale: BOSSBS-9094R-CY7

Descrizione: AHNAK2 contains 1 PDZ (DHR) domain. There are 3 named isoforms of AHNAK2 produced by alternative splicing. AHNAK2 is a 600-kDa protein composed of a large number of highly conserved repeat segments. AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R-A488

Codice articolo locale: BOSSBS-11025R-A488

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R-A555

Codice articolo locale: BOSSBS-11025R-A555

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R-CY5

Codice articolo locale: BOSSBS-11025R-CY5

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R-CY3

Codice articolo locale: BOSSBS-11025R-CY3

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R-A647

Codice articolo locale: BOSSBS-11025R-A647

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11025R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-11025R-CY7

Codice articolo locale: BOSSBS-11025R-CY7

Descrizione: Gigaxonin, also refered to as giant axonal neuropathy, GAN1, or KLHL16, controls protein degradation and is essential for neuronal function and survival. Gigaxonin is a member of the cytoskeletal BTB/kelch repeat family and influences cytoskeletal organization and dynamics, playing a large role in neurofilament architecture. The amino terminal BTB domain of gigaxonin binds to the ubiquitin-activating enzyme E1, while the carboxy-terminal kelch repeat domain interacts directly with the light chain of microtubule-associated protein 1B (MAP1B), and tags it for degredation. Overexpression of MAP1B may lead to neuronal cell death, whereas a reduction of MAP1B significantly improves the survival rate of neurons. Mutations in the Gigaxonin gene result in human giant axonal neuropathy (GAN), an autosomal recessive neurodegenerative disorder characterized by axonal degeneration caused by cytoskeletal abnormalities, including accumulated intermediate filaments.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9094R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-9094R-FITC

Codice articolo locale: BOSSBS-9094R-FITC

Descrizione: AHNAK2 contains 1 PDZ (DHR) domain. There are 3 named isoforms of AHNAK2 produced by alternative splicing. AHNAK2 is a 600-kDa protein composed of a large number of highly conserved repeat segments. AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

UOM: 1 * 100 µl

Promo