Hai cercato: genomes

Codice catalogo: (BOSSBS-8563R)

Fornitore: Bioss

Codice articolo fornitore: BS-8563R

Codice articolo locale: BOSSBS-8563R

Descrizione: KIAA1522 is a 1,035 amino acid protein that exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p35.1. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13444R)

Fornitore: Bioss

Codice articolo fornitore: BS-13444R

Codice articolo locale: BOSSBS-13444R

Descrizione: GLYATL1 is a 302 amino acid mitochondrial acyltransferase that transfers the acyl group to the N-terminus of glycine. GLYATL1 can also conjugate a multitude of substrates to form a variety of N-acylglycines. A member of the glycine N-acyltransferase family, GLYATL1 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q12.1. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15130R)

Fornitore: Bioss

Codice articolo fornitore: BS-15130R

Codice articolo locale: BOSSBS-15130R

Descrizione: The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf88 gene product has been provisionally designated C21orf88 pending further characterization.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15093R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-15093R-FITC

Codice articolo locale: BOSSBS-15093R-FITC

Descrizione: C20orf134 is a 245 amino acid secreted protein that belongs to the Actin family and is encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15093R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-15093R-A647

Codice articolo locale: BOSSBS-15093R-A647

Descrizione: C20orf134 is a 245 amino acid secreted protein that belongs to the Actin family and is encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9054R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-9054R-CY3

Codice articolo locale: BOSSBS-9054R-CY3

Descrizione: DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid ubiquitously expressed protein belonging to the Dom3Z family. The gene encoding DOM3Z maps to human chromosome 6 in the major histocompatibility complex (MHC) class III region. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome are all associated with genes that map to chromosome 6.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9054R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-9054R-A350

Codice articolo locale: BOSSBS-9054R-A350

Descrizione: DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid ubiquitously expressed protein belonging to the Dom3Z family. The gene encoding DOM3Z maps to human chromosome 6 in the major histocompatibility complex (MHC) class III region. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome are all associated with genes that map to chromosome 6.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4291R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-4291R-A350

Codice articolo locale: BOSSBS-4291R-A350

Descrizione: Probable E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a central role in the control of the cell cycle in response to DNA damage. Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function. Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15455R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-15455R-HRP

Codice articolo locale: BOSSBS-15455R-HRP

Descrizione: Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner 'core particle' enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection.The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5424R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-5424R-FITC

Codice articolo locale: BOSSBS-5424R-FITC

Descrizione: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5715R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-5715R-A750

Codice articolo locale: BOSSBS-5715R-A750

Descrizione: Ribosomes, the organelles that catalyse protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L5P family of ribosomal proteins. It is located in the cytoplasm. The protein probably associates with the 5S rRNA. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13315R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-13315R-A750

Codice articolo locale: BOSSBS-13315R-A750

Descrizione: GCN1L1 is a 2,671 amino acid protein that is ubiquitously expressed and belongs to the GCN1 family. Functioning as a translation activator, GCN1L1 interacts with IMPACT to regulproteinate GCN2 kinase activity. GCN1L1 contains 24 HEAT repeats and is encoded by a gene that maps to human chromosome 12q24.23. Chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9982R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-9982R-A750

Codice articolo locale: BOSSBS-9982R-A750

Descrizione: The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukaemias. The C21orf87 gene product has been provisionally designated C21orf87 pending further characterisation.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-15130R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-15130R-CY3

Codice articolo locale: BOSSBS-15130R-CY3

Descrizione: The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf88 gene product has been provisionally designated C21orf88 pending further characterization.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1982R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-1982R-A750

Codice articolo locale: BOSSBS-1982R-A750

Descrizione: MCM3 is one of the highly conserved mini-chromosome maintenance proteins that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-13325R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-13325R-A647

Codice articolo locale: BOSSBS-13325R-A647

Descrizione: GDE4 is a 314 amino acid cytoplasmic and multi-pass membrane protein that belongs to the glycerophosphoryl diester phosphodiesterase family. Expressed in small intestine, placenta, kidney, ovary, thymus, pancreas, spleen, liver and peripheral blood leukocytes, GDE4 contains one GDPD domain and exists as three alternatively spliced isoforms. GDE4 is encoded by a gene that maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1.

UOM: 1 * 100 µl

Promo