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Codice catalogo: (BOSSBS-7551R)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R
Codice articolo locale: BOSSBS-7551R
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-A647
Codice articolo locale: BOSSBS-7551R-A647
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


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Codice catalogo: (BOSSBS-7551R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-A680
Codice articolo locale: BOSSBS-7551R-A680
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterised human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-A350
Codice articolo locale: BOSSBS-7551R-A350
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-CY3
Codice articolo locale: BOSSBS-7551R-CY3
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-CY7
Codice articolo locale: BOSSBS-7551R-CY7
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-FITC
Codice articolo locale: BOSSBS-7551R-FITC
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-A750
Codice articolo locale: BOSSBS-7551R-A750
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterised human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-CY5
Codice articolo locale: BOSSBS-7551R-CY5
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-A555
Codice articolo locale: BOSSBS-7551R-A555
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9568R)
Fornitore: Bioss
Codice articolo fornitore: BS-9568R
Codice articolo locale: BOSSBS-9568R
Descrizione: Abin-1 is a 636 amino acid protein that localizes to both the nucleus and the cytoplasm and is shuttled between the two intercellular regions in a CRM1-dependent manner. Expressed ubiquitously with highest expression in spleen and skeletal muscle, Abin-1 interacts with A20 and, via this interaction, interferes with TRAF2-mediated transactivation signals and effectively inhibits TNF-induced NFâ…¹B expression. Additionally, Abin-1 can be incorporated into HIV-1 virions and, if overexpressed, can inhibit viral replication. Abin-1 may also play an important role in the regulation of nuclear import and export activities. Multiple isoforms of Abin-1 exist due to alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-CY5.5
Codice articolo locale: BOSSBS-7551R-CY5.5
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-A488
Codice articolo locale: BOSSBS-7551R-A488
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7551R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-7551R-HRP
Codice articolo locale: BOSSBS-7551R-HRP
Descrizione: ABIN-3 is a member of the A20-binding inhibitor of NF-kappaB activation (ABIN) protein family. Similar to the previously characterized human ABINs (ABIN-1 and ABIN-2), ABIN-3 can bind to A20 and inhibit NF-kappaB activation. In contrast, mouse ABIN-3 is incapable of inhibiting NF-kappaB activation by proinflammatory stimuli because the protein lacks a complete ABIN homology domain, which is required for the funcitonal activity of human ABIN-3.
UOM: 1 * 100 µl


Codice catalogo: (USBI146495)
Fornitore: US Biological
Codice articolo fornitore: 146495
Codice articolo locale: USBI146495
Descrizione: Anti-TNIP3 Rabbit Polyclonal Antibody
UOM: 1 * 100 µG


Codice catalogo: (PRSI5303)
Fornitore: ProSci Inc.
Codice articolo fornitore: 5303
Codice articolo locale: PRSI5303
Descrizione: ABIN3 Antibody: The nuclear factor NF-kappa B plays key roles in development and immunity. ABIN3 (A20-binding inhibitor of NF-kappa B activation 3), also known as TNFAIP3-interacting protein 3 (TNIP3), is a novel negative feedback regulator of LPS-induced NF-kappa B activation. ABIN3 is a 39 kDa protein that negatively regulates NF-kappa B activation in response to TNF and LPS. ABIN3 is highly expressed in brain, thymus, lymph node, lung and fetal liver, with low expression in kidney, bone marrow. Through its interaction with A20, ABIN3 interferes with TRAF2-mediated transactivation signals and NF-kappa B inhibition is mediated by the ABIN-homology domain 2. ABIN3 has been found to be induced by Listeria infection and can be slightly downregulated by dexamethasone. Enhanced expression of ABIN3 in monocytes is associated with sepsis. Thus, ABIN3 is an IL-10-induced gene product capable of attenuating NF-kappa B in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions. At least four isoforms of ABIN3 are known to exist.
UOM: 1 * 100 µG


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