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Hai cercato: Tyrphostin+AG-126


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Codice catalogo: (BOSSBS-8427R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-8427R-A647
Codice articolo locale: BOSSBS-8427R-A647
Descrizione: BRP44 is a 127 amino acid protein belonging to the UPF0041 family. The gene that encodes BRP44 maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8427R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-8427R-CY5
Codice articolo locale: BOSSBS-8427R-CY5
Descrizione: BRP44 is a 127 amino acid protein belonging to the UPF0041 family. The gene that encodes BRP44 maps to human chromosome 1, which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6643R)
Fornitore: Bioss
Codice articolo fornitore: BS-6643R
Codice articolo locale: BOSSBS-6643R
Descrizione: Defects in GORAB are the cause of geroderma osteodysplasticum (GO) [MIM:231070]; also known as gerodermia osteodysplastica or Walt Disney dwarfism. GO is a rare autosomal recessive disorder characterized by lax, wrinkled skin, joint laxity and a typical face with a prematurely aged appearance. Skeletal signs include severe osteoporosis leading to frequent fractures, malar and mandibular hypoplasia and a variable degree of growth retardation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3140R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-3140R-CY7
Codice articolo locale: BOSSBS-3140R-CY7
Descrizione: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2358R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-2358R-FITC
Codice articolo locale: BOSSBS-2358R-FITC
Descrizione: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1548R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-1548R-CY5
Codice articolo locale: BOSSBS-1548R-CY5
Descrizione: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. recognises and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3140R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-3140R-CY5.5
Codice articolo locale: BOSSBS-3140R-CY5.5
Descrizione: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3140R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-3140R-CY3
Codice articolo locale: BOSSBS-3140R-CY3
Descrizione: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
UOM: 1 * 100 µl


Fornitore: Schott AG
Descrizione: Borosilicate glass tubing, varying types of inner and outer shapes.

Codice catalogo: (BOSSBS-0519R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-A647
Codice articolo locale: BOSSBS-0519R-A647
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0519R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-CY7
Codice articolo locale: BOSSBS-0519R-CY7
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0519R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-A750
Codice articolo locale: BOSSBS-0519R-A750
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl


Codice catalogo: (USBIO8061-100)
Fornitore: US Biological
Codice articolo fornitore: O8061-100
Codice articolo locale: USBIO8061-100
Descrizione: Osteocrin is a recently identified secreted protein expression of which was only detected in bone, peaking just after birth and decreasing markedly with age. A 1280-bp mRNA encodes osteocrin producing a mature protein of 103 amino acids with a molecular mass of 11,4 kD. In primary osteoblastic cell cultures osteocrin expression coincided with matrix formation then decreased in very mature cultures.
UOM: 1 * 100 µG


Codice catalogo: (43868.18)
Fornitore: Thermo Fisher Scientific
Codice articolo fornitore: 43868.18
Codice articolo locale: ALFA43868.18
Descrizione: Standard di argento, Standard for wear metal analysis, 5000 µg/g, Specpure®, Argento, Matrice: Mineral oil, Applicazione: Standard a base di olio
UOM: 1 * 50 g

Codice catalogo: (BOSSBS-0519R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-HRP
Codice articolo locale: BOSSBS-0519R-HRP
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-15066R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-15066R-A555
Codice articolo locale: BOSSBS-15066R-A555
Descrizione: C1orf43, also known as Hepatitis C virus NS5A-transactivated protein 4 and Protein NICE-3, is a 253 amino acid single-pass membrane protein. There are five isoforms of C1orf43 that are produced as a result of alternative splicing events. The gene encoding C1orf43 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM: 1 * 100 µl


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