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Image Unavailable-BOSSBS-13575R-CY3

Anti-ZBTB40 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-13575R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13575R-CY3
Codice articolo locale: BOSSBS-13575R-CY3
Descrizione: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8250R-CY5.5

Anti-DCST1 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-8250R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-8250R-CY5.5
Codice articolo locale: BOSSBS-8250R-CY5.5
Descrizione: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3872R-FITC

Anti-GATA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-3872R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-3872R-FITC
Codice articolo locale: BOSSBS-3872R-FITC
Descrizione: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5890R-A647

Anti-LUM Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-5890R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-5890R-A647
Codice articolo locale: BOSSBS-5890R-A647
Descrizione: Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3541R-A488

Anti-PIN1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-3541R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-3541R-A488
Codice articolo locale: BOSSBS-3541R-A488
Descrizione: Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
UOM: 1 * 100 µl
Image Unavailable-USBIA2296-82A

Anti-AGR2 Rabbit Polyclonal Antibody

Codice catalogo: (USBIA2296-82A)
Fornitore: US Biological
Codice articolo fornitore: A2296-82A
Codice articolo locale: USBIA2296-82A
Descrizione: Anti-AGR2 Rabbit Polyclonal Antibody
UOM: 1 * 50 µG
Image Unavailable-A14235.0F

Isododecane (mixture of isomers) ≥80%, tech.

Fornitore: Thermo Fisher Scientific
Descrizione: Isododecane, mixture of isomer acts as a reaction medium used for polymerisation reactions. It is also useful as an emollient and solvent in skin care products due to its high spreadability, low viscosity and density. It is commonly used in anti-aging serums and also useful in many different cosmetic items like eyeliner, hair care, hair sprays, perfume, conditioners and lotions.

New Product

Image Unavailable-USBIJ0400-01B

Anti-JAG1 Rabbit Polyclonal Antibody

Codice catalogo: (USBIJ0400-01B)
Fornitore: US Biological
Codice articolo fornitore: J0400-01B
Codice articolo locale: USBIJ0400-01B
Descrizione: Anti-JAG1 Rabbit Polyclonal Antibody
UOM: 1 * 250 µG
Image Unavailable-BOSSBS-0177R-PE

Anti-AGER Rabbit Polyclonal Antibody (PE (Phycoerythrin))

Codice catalogo: (BOSSBS-0177R-PE)
Fornitore: Bioss
Codice articolo fornitore: BS-0177R-PE
Codice articolo locale: BOSSBS-0177R-PE
Descrizione: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S1A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides (By similarity). Interaction with S1B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0177R-HRP

Anti-AGER Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-0177R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-0177R-HRP
Codice articolo locale: BOSSBS-0177R-HRP
Descrizione: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S1A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides (By similarity). Interaction with S1B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4890R-A488

Anti-CD24 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-4890R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-4890R-A488
Codice articolo locale: BOSSBS-4890R-A488
Descrizione: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4890R-HRP

Anti-CD24 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-4890R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-4890R-HRP
Codice articolo locale: BOSSBS-4890R-HRP
Descrizione: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4890R-A680

Anti-CD24 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-4890R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-4890R-A680
Codice articolo locale: BOSSBS-4890R-A680
Descrizione: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10283R-FITC

Anti-PHB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-10283R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-FITC
Codice articolo locale: BOSSBS-10283R-FITC
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Image Unavailable-OXOIS611430-6

Ag-AK, Immunofluorescence test, IMAGEN™

Fornitore: THERMO FISHER DIAGNOSTICS
Descrizione: IMAGEN™ is a qualitative direct immunofluorescence test used for detection and confirmation of the presence of virus in cell culture or in clinical specimen.

Product Image-BOSSBS-0517R

Anti-ATF1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-0517R)
Fornitore: Bioss
Codice articolo fornitore: BS-0517R
Codice articolo locale: BOSSBS-0517R
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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