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Erythrosin B disodium salt ≥80%, Sigma-Aldrich®

Fornitore: SIGMA ALDRICH MICROSCOPY
Descrizione: Erythrosin extra bluish is a brown color powder, that is soluble in ethanol and water. Its pH ranges from 2,5 to 4. It is used in color filters, light emitting diodes, cosmetics, hair dyes and more. It has several biological applications like detecting gene expression, treating age related macular degeneration, diabetes, obesity and more.

Certificati

Image Unavailable-BOSSBS-10283R-HRP

Anti-PHB2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-10283R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-HRP
Codice articolo locale: BOSSBS-10283R-HRP
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Image Unavailable-J66601.06

2-O-ɑ-D-glucopyranosyl-L-ascorbic acid 99.5%

Fornitore: Thermo Fisher Scientific
Descrizione: 2-O-alpha-D-Glucopyranosyl-L-ascorbic acid reduces the free radicals that result from UV irradiation of the skin, and significantly reduce cell damage and photo-aging. 2-O-alpha-D-Glucopyranosyl-L-ascorbic acid also promotes collagen synthesis and function as an antioxidant.

Certificati

Image Unavailable-BOSSBS-10283R-CY3

Anti-PHB2 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-10283R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-CY3
Codice articolo locale: BOSSBS-10283R-CY3
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10283R-A750

Anti-Prohibitin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-10283R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-A750
Codice articolo locale: BOSSBS-10283R-A750
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10283R-A350

Anti-PHB2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-10283R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-A350
Codice articolo locale: BOSSBS-10283R-A350
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10283R-A680

Anti-Prohibitin 2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-10283R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-A680
Codice articolo locale: BOSSBS-10283R-A680
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Product Image-BOSSBS-0517R

Anti-ATF1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-0517R)
Fornitore: Bioss
Codice articolo fornitore: BS-0517R
Codice articolo locale: BOSSBS-0517R
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0519R-FITC

Anti-ATF3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-0519R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-FITC
Codice articolo locale: BOSSBS-0519R-FITC
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0519R-CY5.5

Anti-ATF3 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-0519R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-CY5.5
Codice articolo locale: BOSSBS-0519R-CY5.5
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl
Image Unavailable-C80105-25G

Chrysin 97%, Sigma-Aldrich®

Codice catalogo: (C80105-25G)
Fornitore: SIGMA ALDRICH MICROSCOPY
Codice articolo fornitore: C80105-25G
Codice articolo locale: SIAMC80105-25G
Descrizione: Chrysin has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in <i>Escherichia coli</i>. It has been used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line. It has been used to study the effect of chrysin on human ovarian cancer cells.
UOM: 1 * 25 g
Image Unavailable-BOSSBS-0519R-CY3

Anti-ATF3 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-0519R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-CY3
Codice articolo locale: BOSSBS-0519R-CY3
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl
Product Image-PRSI5769

Anti-SIRT4 Chicken Polyclonal Antibody

Codice catalogo: (PRSI5769)
Fornitore: ProSci Inc.
Codice articolo fornitore: 5769
Codice articolo locale: PRSI5769
Descrizione: SIRT4 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.
UOM: 1 * 100 µG
Image Unavailable-BOSSBS-0519R-A680

Anti-ATF3 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-0519R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-A680
Codice articolo locale: BOSSBS-0519R-A680
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3541R-CY5.5

Anti-PIN1 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-3541R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-3541R-CY5.5
Codice articolo locale: BOSSBS-3541R-CY5.5
Descrizione: Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11348R-A555

Anti-HPCA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-11348R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-11348R-A555
Codice articolo locale: BOSSBS-11348R-A555
Descrizione: Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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