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Hai cercato: Tyrphostin+AG+835


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Fornitore: THERMO FISHER DIAGNOSTICS
Descrizione: IMAGEN™ is a qualitative direct immunofluorescence test used for detection and confirmation of the presence of virus in cell culture or in clinical specimen.

Codice catalogo: (BOSSBS-0517R)
Fornitore: Bioss
Codice articolo fornitore: BS-0517R
Codice articolo locale: BOSSBS-0517R
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4890R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-4890R-A647
Codice articolo locale: BOSSBS-4890R-A647
Descrizione: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4890R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-4890R-A555
Codice articolo locale: BOSSBS-4890R-A555
Descrizione: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
UOM: 1 * 100 µl

Certificati


Codice catalogo: (BOSSBS-1449R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-1449R-A350
Codice articolo locale: BOSSBS-1449R-A350
Descrizione: Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-10283R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-CY7
Codice articolo locale: BOSSBS-10283R-CY7
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-10283R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-CY5
Codice articolo locale: BOSSBS-10283R-CY5
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0519R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-FITC
Codice articolo locale: BOSSBS-0519R-FITC
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-0519R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-CY5.5
Codice articolo locale: BOSSBS-0519R-CY5.5
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3541R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-3541R-A750
Codice articolo locale: BOSSBS-3541R-A750
Descrizione: Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically Recognises phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3541R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-3541R-A680
Codice articolo locale: BOSSBS-3541R-A680
Descrizione: Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically Recognises phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
UOM: 1 * 100 µl


Codice catalogo: (C80105-25G)
Fornitore: SIGMA ALDRICH MICROSCOPY
Codice articolo fornitore: C80105-25G
Codice articolo locale: SIAMC80105-25G
Descrizione: Chrysin has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in <i>Escherichia coli</i>. It has been used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line. It has been used to study the effect of chrysin on human ovarian cancer cells.
UOM: 1 * 25 g


Fornitore: Thermo Fisher Scientific
Descrizione: Isododecane, mixture of isomer acts as a reaction medium used for polymerisation reactions. It is also useful as an emollient and solvent in skin care products due to its high spreadability, low viscosity and density. It is commonly used in anti-aging serums and also useful in many different cosmetic items like eyeliner, hair care, hair sprays, perfume, conditioners and lotions.

New Product

Codice catalogo: (USBIC5870-01M)
Fornitore: US Biological
Codice articolo fornitore: C5870-01M
Codice articolo locale: USBIC5870-01M
Descrizione: Anti-CLU Mouse Monoclonal Antibody [clone: 10K73]
UOM: 1 * 500 µG


Codice catalogo: (14199.18)
Fornitore: Thermo Fisher Scientific
Codice articolo fornitore: 14199.18
Codice articolo locale: ALFA14199.18
Descrizione: Standard di argento, Standard for wear metal analysis, 1000 µg/g, Specpure®, Argento, Matrice: oil, Applicazione: Standard a base di olio
UOM: 1 * 50 g

Codice catalogo: (BOSSBS-15066R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-15066R-FITC
Codice articolo locale: BOSSBS-15066R-FITC
Descrizione: C1orf43, also known as Hepatitis C virus NS5A-transactivated protein 4 and Protein NICE-3, is a 253 amino acid single-pass membrane protein. There are five isoforms of C1orf43 that are produced as a result of alternative splicing events. The gene encoding C1orf43 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
UOM: 1 * 100 µl


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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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