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Thymidine-5'-monophosphate disodium salt hydrate ≥98.0% (by HPLC)

Codice catalogo: (TCIAT0845-100MG)

Fornitore: TCI EUROPE

Codice articolo fornitore: T0845-100MG

Codice articolo locale: TCIAT0845-100MG

Descrizione: Thymidine-5'-monophosphate disodium salt hydrate ≥98.0% (by HPLC)

UOM: 1 * 100 mg

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Thymidine-5'-monophosphate disodium salt

Fornitore: Thermo Scientific

Descrizione: Thymidine-5'-monophosphate disodium salt

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Human recombinant thymidylate kinase (from cells)

Codice catalogo: (PRSI92-370)

Fornitore: ProSci Inc.

Codice articolo fornitore: 92-370

Codice articolo locale: PRSI92-370

Descrizione: Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important in the dTTP synthesis pathway for DNA synthesis. It participated in the pyrimidine metabolism pathway and dTTP biosynthesis pathway. DTYMK catalyses the conversion of dTMP to dTDP and catalyses the phosphorylation of thymidine 5'-monophosphate (dTMP) to form thymidine 5'-diphosphate (dTDP) in the presence of ATP and magnesium. Structural and functional analyses suggest that the cDNA codes for authentic human dTMP kinase. The mRNA levels and enzyme activities corresponded to cell cycle progression and cell growth stages.

UOM: 1 * 50 µG

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Anti-TYMS Rabbit Polyclonal Antibody

Codice catalogo: (PRSI30-425)

Fornitore: ProSci Inc.

Codice articolo fornitore: 30-425

Codice articolo locale: PRSI30-425

Descrizione: TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-47 CR601528.1 1-47 48-1099 X02308.1 14-1065 1100-1603 BC083512.1 1067-1570

UOM: 1 * 50 µG

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Anti-ENPP6 Rabbit Polyclonal Antibody

Codice catalogo: (PRSI26-754)

Fornitore: ProSci Inc.

Codice articolo fornitore: 26-754

Codice articolo locale: PRSI26-754

Descrizione: ENPP6 is a choline-specific glycerophosphodiester phosphodiesterase. ENPP6 hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. ENPP6 hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. ENPP6 has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently.

UOM: 1 * 50 µG

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