Hai cercato: Sphingomyelin

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Sphingomyelinase inhibitor

New Product

Fornitore: ENZO LIFE SCIENCES AG

Descrizione: Purified from bovine brain. Contains primarily stearic and nervoic acids. Precursor to ceramide second messengers via the action of sphingomyelinase.

New Product

Codice catalogo: (USBIL9189-95B)

Fornitore: US Biological

Codice articolo fornitore: L9189-95B

Codice articolo locale: USBIL9189-95B

Descrizione: Anti-Sphingomyelin phosphodiesterase 1 Goat Polyclonal Antibody

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-1635R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-CY5

Codice articolo locale: BOSSBS-1635R-CY5

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-A750

Codice articolo locale: BOSSBS-1635R-A750

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-CY3

Codice articolo locale: BOSSBS-1635R-CY3

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-FITC

Codice articolo locale: BOSSBS-1635R-FITC

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-A647

Codice articolo locale: BOSSBS-1635R-A647

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-CY5.5

Codice articolo locale: BOSSBS-1635R-CY5.5

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-A555

Codice articolo locale: BOSSBS-1635R-A555

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1635R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-HRP

Codice articolo locale: BOSSBS-1635R-HRP

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4216R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-4216R-A680

Codice articolo locale: BOSSBS-4216R-A680

Descrizione: Sphingomyelin synthases synthesize the sphingolipid, Sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically Recognises the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4277R)

Fornitore: Bioss

Codice articolo fornitore: BS-4277R

Codice articolo locale: BOSSBS-4277R

Descrizione: Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-4216R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-4216R-A750

Codice articolo locale: BOSSBS-4216R-A750

Descrizione: Sphingomyelin synthases synthesize the sphingolipid, Sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Golgi apparatus SMS1 directly and specifically Recognises the choline head group on the substrate, requiring two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Major form in macrophages. Required for cell growth in certain cell types such as HeLa cells. Suppresses BAX-mediated apoptosis and also prevents cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. May protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.

UOM: 1 * 100 µl

Promo

Fornitore: Apollo Scientific

Descrizione: GW4869 2HCl is a cell permeable, selective and non-competitve inhibitor of N-SMase (neutral sphingomyelinase), which is important in the metabolism of sphingomyelin producing ceramide and phosphocholine and in cell signaling and regulation.

Codice catalogo: (BOSSBS-1635R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-1635R-CY7

Codice articolo locale: BOSSBS-1635R-CY7

Descrizione: Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

UOM: 1 * 100 µl

Promo