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Descrizione: Hypromellose, Substitution Type 2208, 3,550 mPa.s, USP.
Codice catalogo: SPCMHY124-12KG
UOM: 1 * 12 kg
Codice articolo fornitore: HY124-12KG
Codice articolo locale: SPCMHY124-12KG
Fornitore: Spectrum Chemical


Descrizione: Folic acid ≥97.0%, in polvere USP
Codice catalogo: SPCMFO105-25KGBL
UOM: 1 * 25 kg
Codice articolo fornitore: FO105-25KGBL
Codice articolo locale: SPCMFO105-25KGBL
Fornitore: Spectrum Chemical


Descrizione: Cyclohexylamine Hydrochloride is an organic compound that is an aliphatic amine. The compound is a high-melting solid. Cyclohexylamine hydrochloride is used as an intermediate in the synthesis of other organic compounds.
Codice catalogo: SPCMC2127-25KGBL
UOM: 1 * 25 kg
Codice articolo fornitore: C2127-25KGBL
Codice articolo locale: SPCMC2127-25KGBL
Fornitore: Spectrum Chemical


Descrizione: Guanidinio cloruro ≥99%, BiotechGrade
Codice catalogo: SPCMGU103-2.5KG
UOM: 1 * 2,5 kg
Codice articolo fornitore: GU103-2.5KG
Codice articolo locale: SPCMGU103-2.5KG
Fornitore: Spectrum Chemical


Descrizione: trans-Cinnamic acid
Codice catalogo: SPCMCI120-25KGBL
UOM: 1 * 25 kg
Codice articolo fornitore: CI120-25KGBL
Codice articolo locale: SPCMCI120-25KGBL
Fornitore: Spectrum Chemical


Descrizione: Zinc Picolinate, 200 to 400 Mesh, Powder is most commonly used as a nutritional food supplement as a source for zinc and aspartic acid.
Codice catalogo: SPCMZ1088-25KGBL
UOM: 1 * 25 kg
Codice articolo fornitore: Z1088-25KGBL
Codice articolo locale: SPCMZ1088-25KGBL
Fornitore: Spectrum Chemical


Descrizione: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Codice catalogo: BOSSBS-15482R-A750
UOM: 1 * 100 µl
Codice articolo fornitore: BS-15482R-A750
Codice articolo locale: BOSSBS-15482R-A750
Fornitore: Bioss


Descrizione: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. May play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded glycoproteins by association with PNGase and delivering deglycosylated proteins to the proteasome. Involved in global genome nucleotide excision repair (GG-NER) by acting as component of the XPC complex. Cooperatively with CETN2 appears to stabilise XPC. May protect XPC from proteasomal degradation. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Codice catalogo: BOSSBS-15482R-CY5
UOM: 1 * 100 µl
Codice articolo fornitore: BS-15482R-CY5
Codice articolo locale: BOSSBS-15482R-CY5
Fornitore: Bioss


Descrizione: Diaceton alcol
Codice catalogo: SPCMDI102-20LTMT
UOM: 1 * 20 L
Codice articolo fornitore: DI102-20LTMT
Codice articolo locale: SPCMDI102-20LTMT
Fornitore: Spectrum Chemical


Descrizione: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognises a wide spectrum of damaged DNA characterised by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognise and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. <i>in vitro</i>, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.
Codice catalogo: BOSSBS-6634R-A750
UOM: 1 * 100 µl
Codice articolo fornitore: BS-6634R-A750
Codice articolo locale: BOSSBS-6634R-A750
Fornitore: Bioss


Descrizione: 1-Esadecanolo NF
Codice catalogo: SPCMCE120-12KG
UOM: 1 * 12 kg
Codice articolo fornitore: CE120-12KG
Codice articolo locale: SPCMCE120-12KG
Fornitore: Spectrum Chemical


Descrizione: Benzyl Acetate, an organic compound, is the ester formed by condensation of acetic acid and benzyl alcohol; it is the main constituent of the essential oils from jasmine flowers.
Codice catalogo: SPCMB2411-200LTBL
UOM: 1 * 200 L
Codice articolo fornitore: B2411-200LTBL
Codice articolo locale: SPCMB2411-200LTBL
Fornitore: Spectrum Chemical


Descrizione: Benzyltriethylammonium Chloride, also known as Triton B, is a quaternary ammonium salt that functions as an organic base and is a popular phase-transfer catalyst.
Codice catalogo: SPCMB1083-45KGBL
UOM: 1 * 45 kg
Codice articolo fornitore: B1083-45KGBL
Codice articolo locale: SPCMB1083-45KGBL
Fornitore: Spectrum Chemical


Descrizione: Form: Powder
Codice catalogo: SPCMC1890-45KGBL
UOM: 1 * 45 kg
Codice articolo fornitore: C1890-45KGBL
Codice articolo locale: SPCMC1890-45KGBL
Fornitore: Spectrum Chemical


Descrizione: Synonyms: Blancol, naphthalenesulfonic acid, polymer with formaldehyde, sodium salt ; sodium salt of sulphonated naphthaleneformaldehyde condensate.
Codice catalogo: SPCMS1161-100GM
UOM: 1 * 100 g
Codice articolo fornitore: S1161-100GM
Codice articolo locale: SPCMS1161-100GM
Fornitore: Spectrum Chemical


Descrizione: BSE/TSE statement (available upon request)
Allergen statement (available upon request)
Codice catalogo: SPCMP1058-100GM
UOM: 1 * 100 g
Codice articolo fornitore: P1058-100GM
Codice articolo locale: SPCMP1058-100GM
Fornitore: Spectrum Chemical