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Fornitore: Biotium
Descrizione: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Codice catalogo: (BNUM0372-50)
Fornitore: Biotium
Codice articolo fornitore: BNUM0372-50
Codice articolo locale: BTIUBNUM0372-50
Descrizione: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
UOM: 1 * 50 µl


Codice catalogo: (BOSSBS-4901R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-4901R-HRP
Codice articolo locale: BOSSBS-4901R-HRP
Descrizione: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1437R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-1437R-A350
Codice articolo locale: BOSSBS-1437R-A350
Descrizione: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
UOM: 1 * 100 µl


Codice catalogo: (20340-500UL)
Fornitore: Biotium
Codice articolo fornitore: 20340-500UL
Codice articolo locale: BTIU20340-500UL
Descrizione: CF™405 antibodies are affinity-purified antibodies labeled with blue fluorescent CF™405S or CF™405M, two members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 0,5 mL


Fornitore: Biotium
Descrizione: This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Fornitore: Biotium
Descrizione: This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

Codice catalogo: (BOSSBS-11841R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11841R-CY3
Codice articolo locale: BOSSBS-11841R-CY3
Descrizione: TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl


Codice catalogo: (20338-500UL)
Fornitore: Biotium
Codice articolo fornitore: 20338-500UL
Codice articolo locale: BTIU20338-500UL
Descrizione: CF™568 antibodies are affinity-purified antibodies labeled with red fluorescent CF™568, a member of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 0,5 mL


Codice catalogo: (20366-500UL)
Fornitore: Biotium
Codice articolo fornitore: 20366-500UL
Codice articolo locale: BTIU20366-500UL
Descrizione: CF™532 antibodies are affinity-purified antibodies labeled with orange fluorescent CF™532 (Ex/Em: 527/558nm), a member of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 0,5 mL


Codice catalogo: (20333-500UL)
Fornitore: Biotium
Codice articolo fornitore: 20333-500UL
Codice articolo locale: BTIU20333-500UL
Descrizione: CF™543 antibodies are affinity-purified antibodies labeled with orange fluorescent CF™543 (Ex/Em 541/560nm), a member of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 0,5 mL


Codice catalogo: (BOSSBS-10516R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-10516R-A488
Codice articolo locale: BOSSBS-10516R-A488
Descrizione: This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
UOM: 1 * 100 µl


Codice catalogo: (20344-50UL)
Fornitore: Biotium
Codice articolo fornitore: 20344-50UL
Codice articolo locale: BTIU20344-50UL
Descrizione: Near-infrared CF™ dye antibodies are affinity-purified antibodies labeled with near-infrared fluorescent CF™750 or CF™770, two members of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 50 µl


Codice catalogo: (20346-250UL)
Fornitore: Biotium
Codice articolo fornitore: 20346-250UL
Codice articolo locale: BTIU20346-250UL
Descrizione: CF™647 antibodies are affinity-purified antibodies labeled with far-red fluorescent CF™647, a member of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 0,25 mL


Codice catalogo: (20341-500UL)
Fornitore: Biotium
Codice articolo fornitore: 20341-500UL
Codice articolo locale: BTIU20341-500UL
Descrizione: CF™633 antibodies are affinity-purified antibodies labeled with far-red fluorescent CF™633, a member of the novel CF™ dye series developed by Biotium for labeling proteins and other biomolecules. CF™ dyes are designed to offer advantages in brightness, photostability, and/or specificity compared to other commercial dyes, and are available in colors spanning the visible, far-red, and near-infrared spectra.
UOM: 1 * 0,5 mL


Codice catalogo: (BOSSBS-6096R)
Fornitore: Bioss
Codice articolo fornitore: BS-6096R
Codice articolo locale: BOSSBS-6096R
Descrizione: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
UOM: 1 * 100 µl


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