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Fornitore: ENZO LIFE SCIENCES AG
Descrizione: Prostanoid receptor ligand.

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Codice catalogo: (USBIP9053-26C1)
Fornitore: US Biological
Codice articolo fornitore: P9053-26C1
Codice articolo locale: USBIP9053-26C1
Descrizione: Anti-Prostaglandin D2 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


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Codice catalogo: (USBIP9053-24B)
Fornitore: US Biological
Codice articolo fornitore: P9053-24B
Codice articolo locale: USBIP9053-24B
Descrizione: Anti-Prostaglandin D2 Synthase Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


Fornitore: Cayman Chemical
Descrizione: Prostaglandin D₂ Express ELISA kit is a competitive assay that can be used for quantification of PGD₂.

Fornitore: ENZO LIFE SCIENCES AG
Descrizione: Prostaglandin D2 derived nuclear peroxisome proliferator-activated receptor γ (PPARγ) ligand. Induces apoptosis in a number of cell types including human lung cancer cells, synoviocytes and macrophages. Promotes differentiation of fibroblasts to adipocytes. Antiinflammatory activity. Inhibits angiogenesis. Prevents TNFα induced leptin increase in mice. TRPA1 agonist. Serious doubts as to the biological relevance of this prostaglandin have been raised. Endogenous levels seem to be too low to have any effect as a PPARγ ligand.

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Codice catalogo: (BOSSBS-13537R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-CY7
Codice articolo locale: BOSSBS-13537R-CY7
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-FITC
Codice articolo locale: BOSSBS-13537R-FITC
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-A555
Codice articolo locale: BOSSBS-13537R-A555
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-HRP
Codice articolo locale: BOSSBS-13537R-HRP
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-A680
Codice articolo locale: BOSSBS-13537R-A680
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-CY5
Codice articolo locale: BOSSBS-13537R-CY5
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-CY3
Codice articolo locale: BOSSBS-13537R-CY3
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-A350
Codice articolo locale: BOSSBS-13537R-A350
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-A488
Codice articolo locale: BOSSBS-13537R-A488
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13537R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-13537R-A647
Codice articolo locale: BOSSBS-13537R-A647
Descrizione: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
UOM: 1 * 100 µl


Codice catalogo: (ENZOADI905800100)
Fornitore: ENZO LIFE SCIENCES AG
Codice articolo fornitore: ADI905800100
Codice articolo locale: ENZOADI905800100
Descrizione: The conversion of arachidonic acid to prostaglandin H2 (PGH2) by cyclooxygenase (COX) enzymes is the first step in the synthesis of prostanoids. Prostaglandin D2 (PGD2) is synthesized from PGH2 by the action of PGD synthase, and its actions in vasodilation and platelet activation are mediated via activation of two identified G-protein coupled receptors (GPCRs): DP1 and DP2 (formerly CRTH2). Both DP1 and DP2 receptors are coupled to Gs alpha subunits, resulting in increased adenylyl cyclase activity and cAMP production upon agonist binding. DP1 receptor is expressed moderately in the ileum and weakly in the lung, stomach, and uterus of mice, and weakly in the small intestine of humans. In rodents, expression of PGD synthase and the DP1 receptor is seen in the leptomeninges, where it is believed they play a role in the induction of sleep. The DP1 receptor may also oppose DP2-mediated activation of basophils, eosinophils, and Th2 cells.
UOM: 1 * 100 µG

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