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Image Unavailable-BOSSBS-7048R-FITC

Anti-INPPL1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Descrizione: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Codice catalogo: BOSSBS-7048R-FITC
UOM: 1 * 100 µl
Codice articolo fornitore: BS-7048R-FITC
Codice articolo locale: BOSSBS-7048R-FITC
Fornitore: Bioss
Image Unavailable-BOSSBS-7048R-CY3

Anti-INPPL1 Rabbit Polyclonal Antibody (Cy3®)

Descrizione: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Codice catalogo: BOSSBS-7048R-CY3
UOM: 1 * 100 µl
Codice articolo fornitore: BS-7048R-CY3
Codice articolo locale: BOSSBS-7048R-CY3
Fornitore: Bioss
Image Unavailable-BOSSBS-7048R-A350

Anti-INPPL1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Descrizione: Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
Codice catalogo: BOSSBS-7048R-A350
UOM: 1 * 100 µl
Codice articolo fornitore: BS-7048R-A350
Codice articolo locale: BOSSBS-7048R-A350
Fornitore: Bioss
Product Image-461-1428

Immersion thermostats, MAGIO™ MS and MX

Descrizione: The MAGIO™ series of bridge mounted circulators operate with a working temperature range of −50 to +300 °C* and a heating capacity of up to 3 kW. With their powerful pressure/suction pump the MAGIO™ units are ideal for external temperature applications. An extensive range of accessories and excellent dynamics mean that the MAGIO™ immersion thermostats can be adapted to different tanks and applications.
Codice catalogo: 461-1428
UOM: 1 * 1 pezzi
Codice articolo fornitore: 9033201
Codice articolo locale: JULA9033201
Fornitore: Julabo GmbH
Image Unavailable-PRCI1400-20-PDC

Lab Markers, several colours

Descrizione: Versatile, permanent markings write on plastic, metal, and porcelain labware.
Codice catalogo: PRCI1400-20-PDC
UOM: 1 * 10 pezzi
Codice articolo fornitore: 1400-20-PDC
Codice articolo locale: PRCI1400-20-PDC
Fornitore: PRECISION DYNAMICS
Product Image-611-2581

Bilance industriali, bilancia da banco compatta Ranger® 3000

Descrizione: Bilancia multiuso compatta e semplice da utilizzare per risultati rapidi e precisi. Le modalità di applicazione includono: pesata, pesata percentuale, conteggio pezzi, accumulazione e pesatura dinamica.
Codice catalogo: 611-2581
UOM: 1 * 1 pezzi
Codice articolo fornitore: 30031702
Codice articolo locale: OHAU30031702
Fornitore: OHAUS
Product Image-611-3408

Bilance da banco industriali, Ranger serie 4000

Descrizione: Bilancia multiuso compatta per la produzione rapida di risultati precisi. Modalità di applicazione: pesata, pesata percentuale, conteggio dei pezzi, accumulazione e pesatura dinamica e funzione hold del display
Codice catalogo: 611-3408
UOM: 1 * 1 pezzi
Codice articolo fornitore: 30231099
Codice articolo locale: OHAU30231099
Fornitore: OHAUS
Image Unavailable-PRTWDX474MBRL

DX4™ Softshell Jackets

Descrizione: The DX4 Softshell jacket is precision engineered using a revolutionary breathable, waterproof, and windproof ripstop fabric. Its sports inspired design includes longer back length, dynamic shaped sleeves, adjustable cuffs, reflective trims, and multiple secure pockets for ample storage. An ideal choice for the modern worker.
Codice catalogo: PRTWDX474MBRL
UOM: 1 * 1 pezzi
Codice articolo fornitore: DX474MBRL
Codice articolo locale: PRTWDX474MBRL
Fornitore: Portwest
Product Image-PRTWDX474BKRM

Softshell jackets, DX4™, DX474

Descrizione: The DX4™ Softshell Jackets are precision engineered using a revolutionary breathable, waterproof and windproof ripstop fabric. These sports inspired design includes longer back length, dynamic shaped sleeves, adjustable cuffs, reflective trims and multiple secure pockets for ample storage. An ideal choice for the modern worker.
Codice catalogo: PRTWDX474BKRM
UOM: 1 * 1 pezzi
Codice articolo fornitore: DX474BKRM
Codice articolo locale: PRTWDX474BKRM
Fornitore: Portwest
Product Image-611-3225

Bilance di precisione, Adventurer®

Descrizione: Una gamma di bilance con numerose funzionalità e semplici da utilizzare, per risultati di pesata rapidi e accurati nelle attività di pesatura e misurazione di routine. Le applicazioni comprendono pesata, formulazione, pesata dinamica, conteggio delle parti, totalizzazione, determinazione della densità, controllo della pesata e pesata in percentuale. I tipici tempi di stabilizzazione sono meno di 2 secondi.
Codice catalogo: 611-3225
UOM: 1 * 1 pezzi
Codice articolo fornitore: 30127962
Codice articolo locale: OHAU30127962
Fornitore: OHAUS
Product Image-RPN2232

Western blotting detection reagent, Amersham™ ECL™ Prime

Descrizione: Amersham™ ECL™ Prime is a highly sensitive Western blotting detection reagent characterised by stable signal emission, allowing for the possibility of repeated exposures and making it easier to process several blots in the same experimental run. Amersham™ ECL™ Prime delivers a detection system that is sensitive, stable, precisely quantitative across a wide dynamic range of protein levels, and conservative in its consumption of expensive antibody reagents. The high performance of Amersham™ ECL™ Prime is due to the presence of an enhancer in the reagent, increasing enzyme turnover, and thereby significantly increasing both signal intensity and duration. The light signal is further intensified by the addition of a catalyst.
Codice catalogo: RPN2232
UOM: 1 * 1 KIT
Codice articolo fornitore: RPN2232
Codice articolo locale: GEHERPN2232
Fornitore: Cytiva
Product Image-461-1423

Termostati, Serie MAGIO™ MS e MX

Descrizione: MAGIO™ funziona con un range di temperatura da 20 a +300 °C e potenza termica fino a 3 kW. Con la loro potente pompa di pressione/aspirazione, le unità MAGIO™ sono ideali per applicazioni di controllo esterno della temperatura. Un'ampia gamma di accessori e un'eccellente dinamica fanno sì che i circolatori MAGIO™ possano essere adattati modularmente e specifico per le diverse applicazioni.
Codice catalogo: 461-1423
UOM: 1 * 1 pezzi
Codice articolo fornitore: 9032504
Codice articolo locale: JULA9032504
Fornitore: Julabo GmbH
Product Image-471-1051

Frigoriferi da laboratorio, Compact, Mediline

Descrizione: Questi frigoriferi da laboratorio MediLine dotati di funzione comfort controller, forniscono il massimo spazio di conservazione su un ingombro di 60 cm di larghezza. I modelli sottobanco sono alti 820 mm e entrano sotto quasi tutti i banchi da laboratorio. Questi apparecchi soddisfano le rigide esigenze di refrigerazione di laboratorio.
Codice catalogo: 471-1051
UOM: 1 * 1 pezzi
Codice articolo fornitore: LKUV1613
Codice articolo locale: LIEBLKUV1613
Fornitore: Liebherr
Product Image-LAUDL002681

Heating and cooling process thermostats, Integral XT

Descrizione: Process thermostats with integrated cooling system for dynamic temperature control within external circuits.
Codice catalogo: LAUDL002681
UOM: 1 * 1 pezzi
Codice articolo fornitore: L002681
Codice articolo locale: LAUDL002681
Fornitore: LAUDA

New Product


Product Image-462-0639

Circolatori refrigerati e riscaldanti, MAGIO™ serie MS

Descrizione: La serie MAGIO™ di circolatori refrigeranti e riscaldanti funzionano con una gamma di temperatura operativa che va da –50 a +300 °C e con una capacità riscaldante fino a 3 kW. Con la loro potente pompa di pressione/aspirazione, le unità MAGIO™ sono ideali per applicazioni a temperatura esterna. Una vasta gamma di accessori e un'eccellente dinamica fanno sì che i circolatori MAGIO™ possano essere adattati in modo modulare e individuale alle applicazioni.
Codice catalogo: 462-0639
UOM: 1 * 1 pezzi
Codice articolo fornitore: 9032714.S1
Codice articolo locale: JULA9032714.S1
Fornitore: Julabo GmbH

Environmentally Preferable


Product Image-LAUDL002663

Heating and cooling process thermostats, Integral T

Descrizione: Integral T are process thermostats with an integrated cooling system for dynamic temperature control within external circuits.
Codice catalogo: LAUDL002663
UOM: 1 * 1 pezzi
Codice articolo fornitore: L002663
Codice articolo locale: LAUDL002663
Fornitore: LAUDA
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