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Product Image-BOSSBS-2888R

Anti-TRPM2 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-2888R)
Fornitore: Bioss
Codice articolo fornitore: BS-2888R
Codice articolo locale: BOSSBS-2888R
Descrizione: Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0980R-CY5.5

Anti-CD38 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-0980R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-0980R-CY5.5
Codice articolo locale: BOSSBS-0980R-CY5.5
Descrizione: Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
UOM: 1 * 100 µl

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Image Unavailable-BOSSBS-5915R-HRP

Anti-MBD1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-5915R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-5915R-HRP
Codice articolo locale: BOSSBS-5915R-HRP
Descrizione: DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3497R-A680

Anti-p40phox Thr154 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-3497R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-3497R-A680
Codice articolo locale: BOSSBS-3497R-A680
Descrizione: NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3616R-HRP

Anti-NCF/NCF4/p40phox Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-3616R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-3616R-HRP
Codice articolo locale: BOSSBS-3616R-HRP
Descrizione: NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3616R-A647

Anti-NCF/NCF4/p40phox Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-3616R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-3616R-A647
Codice articolo locale: BOSSBS-3616R-A647
Descrizione: NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
UOM: 1 * 100 µl
Product Image-22682.265

Cloralio idrato, GPR RECTAPUR®

Codice catalogo: (22682.265)
Fornitore: VWR Chemicals
Codice articolo locale: VWRC22682.265
Descrizione: Cloralio idrato, GPR RECTAPUR®
UOM: 1 * 500 g

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Image Unavailable-BOSSBS-11738R-HRP

Anti-NMNAT1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-11738R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-11738R-HRP
Codice articolo locale: BOSSBS-11738R-HRP
Descrizione: Nicotinamide adenine dinucleotide (NMNAT) is an essential cofactor involved in fundamental processes in cell metabolism. NMNAT plays a key role in NAD(+) biosynthesis, catalysing the condensation of nicotinamide mononucleotide and ATP, and yielding NAD(+) and pyrophosphate. NMNAT appears to be a substrate of nuclear kinases and contains at least three potential phosphorylation sites. The interaction of NMNAT with nuclear proteins is likely to be modulated by phosphorylation. NMNAT is widely expressed with highest levels in skeletal muscle, heart, liver and kidney.
UOM: 1 * 100 µl
Product Image-BOSSBS-4164R

Anti-SLC52A3 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-4164R)
Fornitore: Bioss
Codice articolo fornitore: BS-4164R
Codice articolo locale: BOSSBS-4164R
Descrizione: Transporter for riboflavin, which must be obtained as a nutrient via intestinal absorption. Riboflavin transport is Na(+)-independent at low pH but significantly reduced by Na(+) depletion under neutral pH conditions. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin, flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD), by methylene blue, and to a lesser extent by amiloride.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5915R-CY3

Anti-MBD1 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-5915R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-5915R-CY3
Codice articolo locale: BOSSBS-5915R-CY3
Descrizione: DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5915R-A555

Anti-MBD1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-5915R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-5915R-A555
Codice articolo locale: BOSSBS-5915R-A555
Descrizione: DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5915R-A647

Anti-MBD1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-5915R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-5915R-A647
Codice articolo locale: BOSSBS-5915R-A647
Descrizione: DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5915R-CY5

Anti-MBD1 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-5915R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-5915R-CY5
Codice articolo locale: BOSSBS-5915R-CY5
Descrizione: DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3497R

Anti-NCF4 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-3497R)
Fornitore: Bioss
Codice articolo fornitore: BS-3497R
Codice articolo locale: BOSSBS-3497R
Descrizione: NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3616R-CY5.5

Anti-NCF/NCF4/p40phox Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-3616R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-3616R-CY5.5
Codice articolo locale: BOSSBS-3616R-CY5.5
Descrizione: NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3616R-CY7

Anti-NCF/NCF4/p40phox Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-3616R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-3616R-CY7
Codice articolo locale: BOSSBS-3616R-CY7
Descrizione: NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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