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Hai cercato: Neu5Ac-alpha(2-3)Gal-beta-MP+Glycoside


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Codice catalogo: (TCIAR0237-1VIAL)
Fornitore: TCI
Codice articolo fornitore: R0237-1VIAL
Codice articolo locale: TCIAR0237-1VIAL
Descrizione: The rMOA is an Escherichia coli recombinant of carbohydrate-binding protein (Lectin) derived from Marasmius oreades. This lectin preferably binds to a [Galα(1-3)Gal] glycan epitope (It very slightly interacts with melibiose).
The LecBeads is a lectin-immobilized agarose which is capable of capturing glycoproteins via binding to its specific epitope(s), and it is prepared by a covalent coupling method between lectin and agarose.
The Lectin-catch method using LecBeads (as shown in Application tab) is available for selective separation of glycoconjugates (glycoproteins, glycolipids, and so on). This rMOA1a-LecBeads (1 ml gel) shows a binding capacity of about 10 mg or more Cetuximab through its binding to a terminal [Galα(1-3)Gal] glycan epitope on Cetuximab.
UOM: 1 * 1 Vial


Fornitore: MP Biomedicals
Descrizione: Salicin is an alcoholic β-glucoside derived from willow bark that produces anti-inflammatory (including analgesic and antipyretic) effects very similar to that of aspirin Salicin is a substrate for β-glucosidase.

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Fornitore: MP Biomedicals
Descrizione: Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of adeoxyribose ring it is known as deoxyguanosine.
Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein. The antiviral drug aciclovir, often used in herpes treatment, is structurally similar to guanosine.

Codice catalogo: (BOSSBS-8032R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-8032R-CY3
Codice articolo locale: BOSSBS-8032R-CY3
Descrizione: COLEC11 is a 271 amino acid C-type lectin protein that contains a collagen-like domain and a carbohydrate recognition domain, and plays an important role in host-defense. COLEC11 binds to various sugars and LPS (lipopolysaccharides), which include fucose but does not bind to glucose, hnRNP, Beta-1,3-Gal-T3 or mannose. COLEC11 is ubiquitously expressed in most tissues with high expression in kidney, liver, fetal liver, small intestine, thymus, spinal cord, placenta, adrenal gland, pancreas and several cell lines. COLEC11 is a secreted protein and all alternatively spliced isoforms of COLEC11 have oligomeric structures created through disulfide bonding.
UOM: 1 * 100 µl


Fornitore: ENZO LIFE SCIENCES
Descrizione: MHC ligand.

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Fornitore: MP Biomedicals
Descrizione: Storage: Store at room Temperature (15-30 °C)
Sucrose is a nonreducing disaccharide composed of glucose and fructose, linked via their anomeric carbons. It is obtained commercially from Sugarcane, sugar beet (Beta vulgaris), and other plants and used extensively as a food and a sweetener.
Use to create sucrose gradients for purification of viruses and proteins.

Fornitore: TCI
Descrizione: N-Acetylneuraminic acid hydrate ≥98.0% (by titrimetric analysis)

Codice catalogo: (BOSSBS-13271R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-13271R-CY5
Codice articolo locale: BOSSBS-13271R-CY5
Descrizione: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T11 (Polypeptide N-acetylgalactosaminyltransferase 11), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11, is a 608 amino acid protein that catalyzes glycosylation of Muc1, Muc4.1 and EA2, though it does not display enzymatic preference for erythropoitein. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T11 is highly expressed in kidney tubules, though it is not expressed in glomeruli. There are two isoforms of GalNAc-T11 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


Fornitore: MP Biomedicals
Descrizione: Agar is a polysaccharide complex extracted by bleaching and hot water treatment of agarocytes from the red alga Rhodophyceae, and usually consisting of the genera Gelidium, Acanthopeltis, Ceramium, Pterocladia and Gracilaria. The algae are typically found in the Pacific and Indian Oceans and in the Sea of Japan. It is primarily composed of two different units: Agarose and Agaropectin; Agarose is a neutral gelling component which is composed of a linear polymer of alternating D-galactose and 3,6-anhydrogalactose units. Agaropectin is a non-gelling component which consists of D-1,3-glycosidically linked D-galactose units, some of which are sulfated at the 6th position.
Agar is typically used in (According to the Merck Index): Substitute for gelatin, isinglass, etc. in making emulsions including photographic, gels in cosmetics, and as thickening agent in foods especially confectionaries and dairy products; in meat canning; in production of medicinal encapsulations and ointments; as dental impression mold base; as corrosion inhibitor; sizing for silks and paper; in the dyeing and printing of fabrics and textiles; in adhesives. In nutrient media for bacterial cultures.

Fornitore: MP Biomedicals
Descrizione: Simple carbohydrate. Sucrose is hydrolyzed to glucose and fructose by dilute acids and by invertase, a yeast enzyme. Upon hydrolysis the optical rotation falls and is negative when the hydrolysis is complete. The mixture of glucose and fructose is known as "Invert sugar".

Codice catalogo: (BOSSBS-13271R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-13271R-A750
Codice articolo locale: BOSSBS-13271R-A750
Descrizione: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T11 (Polypeptide N-acetylgalactosaminyltransferase 11), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11, is a 608 amino acid protein that catalyzes glycosylation of Muc1, Muc4.1 and EA2, though it does not display enzymatic preference for erythropoitein. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T11 is highly expressed in kidney tubules, though it is not expressed in glomeruli. There are two isoforms of GalNAc-T11 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13271R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13271R-FITC
Codice articolo locale: BOSSBS-13271R-FITC
Descrizione: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T11 (Polypeptide N-acetylgalactosaminyltransferase 11), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11, is a 608 amino acid protein that catalyzes glycosylation of Muc1, Muc4.1 and EA2, though it does not display enzymatic preference for erythropoitein. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T11 is highly expressed in kidney tubules, though it is not expressed in glomeruli. There are two isoforms of GalNAc-T11 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13270R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-13270R-A647
Codice articolo locale: BOSSBS-13270R-A647
Descrizione: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues of various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T10 (Polypeptide N-acetylgalactosaminyltransferase 10), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10, is a 603 amino acid single-pass type II membrane protein that prefers Muc5Ac and EA2 peptide substrates. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. GalNAc-T10 is widely expressed, with highest levels found in small intestine. There are four isoforms of GalNAc-T10 that are produced as a result of alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13274R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13274R-CY3
Codice articolo locale: BOSSBS-13274R-CY3
Descrizione: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13274R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-13274R-A647
Codice articolo locale: BOSSBS-13274R-A647
Descrizione: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13274R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-13274R-CY7
Codice articolo locale: BOSSBS-13274R-CY7
Descrizione: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosamine) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-T13 (Polypeptide N-acetylgalactosaminyltransferase 13), also known as UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 13, is a 556 amino acid protein that displays much stronger enzymatic activity than GalNAc-1 towards GalNAc transfer to mucin peptides such as Muc5a and Muc7. The N-terminal domain is involved in substrate binding and manganese coordination, while the C-terminal domain is involved in UDP-Gal binding and catalytic reaction. With specific expression in the central nervous system, GalNAc-T13 may be responsible for the synthesis of Tn antigen in neuronal cells, which is a universal carcinoma marker on malignant cells.
UOM: 1 * 100 µl


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