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Hai cercato: NF-\\u03BAB+Activation+Inhibitor+III


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Fornitore: Cayman Chemical
Descrizione: NF-κB Activation Inhibitor III ≥99%

Fornitore: Cayman Chemical
Descrizione: A synthetic peptide corresponding to the nuclear localisation sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells; blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.

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ULTERIORI INFORMAZIONI

fino a 10 l, tipo 1/al giorno

ACQUISTA ORA
Codice catalogo: (BOSSBS-6202R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R-CY5
Codice articolo locale: BOSSBS-6202R-CY5
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Codice catalogo: (ENZOALX350109MC05)
Fornitore: ENZO LIFE SCIENCES AG
Codice articolo fornitore: ALX350109MC05
Codice articolo locale: ENZOALX350109MC05
Descrizione: Antibiotic. Inhibitor of NF-κB activation by preventing the phosphorylation of IκB protein and thereby interrupts the signalling pathway. Strongly inhibits the expression of several NF-κB dependent pro-inflammatory genes.
UOM: 1 * 0,5 mg

New Product


Codice catalogo: (BOSSBS-6202R)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R
Codice articolo locale: BOSSBS-6202R
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6202R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R-CY5.5
Codice articolo locale: BOSSBS-6202R-CY5.5
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6202R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R-CY7
Codice articolo locale: BOSSBS-6202R-CY7
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Fornitore: ENZO LIFE SCIENCES AG
Descrizione: Competitive inhibitor of HMG-CoA reductase. Suppresses TNF-induced NF-κB activation.

New Product

Codice catalogo: (BOSSBS-3232R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-3232R-CY7
Codice articolo locale: BOSSBS-3232R-CY7
Descrizione: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6202R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R-A680
Codice articolo locale: BOSSBS-6202R-A680
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3232R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-3232R-CY5.5
Codice articolo locale: BOSSBS-3232R-CY5.5
Descrizione: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3232R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-3232R-A350
Codice articolo locale: BOSSBS-3232R-A350
Descrizione: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6202R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R-A350
Codice articolo locale: BOSSBS-6202R-A350
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6202R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R-FITC
Codice articolo locale: BOSSBS-6202R-FITC
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6202R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-6202R-CY3
Codice articolo locale: BOSSBS-6202R-CY3
Descrizione: Could be involved in the activation of both NF-kappa-B via a NF-kappa-B inhibitor kinase (IKK)-dependent mechanism and stress-activated protein kinase (SAPK)/JNK.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3232R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-3232R-A555
Codice articolo locale: BOSSBS-3232R-A555
Descrizione: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE. IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Also phosphorylates other substrates including NCOA3, BCL10 and IRS1. Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation.
UOM: 1 * 100 µl


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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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