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Image Unavailable-BOSSBS-11352R-A680

Anti-MAGI1/IRSP58 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-11352R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11352R-A680
Codice articolo locale: BOSSBS-11352R-A680
Descrizione: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localisation signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localised to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11352R-A750

Anti-MAGI1/IRSP58 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Codice catalogo: (BOSSBS-11352R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11352R-A750
Codice articolo locale: BOSSBS-11352R-A750
Descrizione: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localisation signal that localises MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localised to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
UOM: 1 * 100 µl
Product Image-USBI138546-100

Anti-Epithelial Membrane Antigen Mouse Monoclonal Antibody [clone: E29]

Codice catalogo: (USBI138546-100)
Fornitore: US Biological
Codice articolo fornitore: 138546-100
Codice articolo locale: USBI138546-100
Descrizione: Anti-Epithelial Membrane Antigen Mouse Monoclonal Antibody [clone: E29]
UOM: 1 * 100 µl
Image Unavailable-548-9043A

VWR® Filter Vials

Fornitore: VWR Collection
Descrizione: Filter vials with the membrane, PE snap ring cap (11 mm), with hole and silicone white/PTFE red septa.

Image Unavailable-BOSSBS-0886R-CY5

Anti-Measles virus fusion Protein Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-0886R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-0886R-CY5
Codice articolo locale: BOSSBS-0886R-CY5
Descrizione: Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. This fusion is pH independent and occurs directly at the outer cell membrane. The trimer of F1-F2 (F protein) probably interacts with H at the virion surface. Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes. Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
UOM: 1 * 100 µl
Product Image-SART17655

Accessories for AirPort MD8

Fornitore: Sartorius
Descrizione: Adattatore di membrane in gelatina

Image Unavailable-BNC680968-500

Anti-CD63 Mouse Monoclonal Antibody (CF568) [clone: LAMP3/968]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BNC050968-500

Anti-CD63 Mouse Monoclonal Antibody (CF405M) [clone: LAMP3/968]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BNC040968-100

Anti-CD63 Mouse Monoclonal Antibody (CF405S) [clone: LAMP3/968]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BNC880525-100

Anti-CD63 Mouse Monoclonal Antibody (CF488A) [clone: MX-49.129.5]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BNC470525-100

Anti-CD63 Mouse Monoclonal Antibody (CF647) [clone: MX-49.129.5]

Fornitore: Biotium
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Image Unavailable-BNUM0186-50

Anti-CD63 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: NKI-C3]

Codice catalogo: (BNUM0186-50)
Fornitore: Biotium
Codice articolo fornitore: BNUM0186-50
Codice articolo locale: BTIUBNUM0186-50
Descrizione: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
UOM: 1 * 50 µl
Image Unavailable-63086-50MG-F

Magnesium ionophore III, Selectophore™, function tested ionophore, Supelco®

Codice catalogo: (63086-50MG-F)
Fornitore: Merck
Codice articolo fornitore: 63086-50MG-F
Codice articolo locale: SUPL63086-50MG-F
Descrizione: Ionophore used in solvent polymeric membrane electrodes for the assay of Mg2+ activities in blood serum
UOM: 1 * 50 mg
Image Unavailable-ABCAAB190725-500

Anti-Nuclear Membrane Marker Mouse Monoclonal Antibody [clone: NM97]

Codice catalogo: (ABCAAB190725-500)
Fornitore: Abcam
Codice articolo fornitore: AB190725-500
Codice articolo locale: ABCAAB190725-500
Descrizione: Mouse monoclonal [NM97] to Nuclear Membrane Marker.
UOM: 1 * 500 µl
Product Image-MILFXFUF07601

Solvent-Resistant Stirred Cell for 76 mm Membranes

Codice catalogo: (MILFXFUF07601)
Fornitore: Merck
Codice articolo fornitore: XFUF07601
Codice articolo locale: MILFXFUF07601
Descrizione: For applications requiring compatibility with solvents, this Millipore stirred cell is available in two sizes. Certain aldehydes, ketones (e.g., acetone) and aliphatic ethers/esters may reduce the life of the fluorocarbon O-rings.
UOM: 1 * 1 pezzi
Image Unavailable-BOSSBS-4258R-A750

Anti-Vesicle docking protein p115 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-4258R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-4258R-A750
Codice articolo locale: BOSSBS-4258R-A750
Descrizione: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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