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Fornitore: Corning
Descrizione: Track-etched PET membranes have a smooth surface and defined cylindrical pores that traverse the membrane.
Codice catalogo: (BOSSBS-9717R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-9717R-A680
Codice articolo locale: BOSSBS-9717R-A680
Descrizione: Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9717R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-9717R-CY7
Codice articolo locale: BOSSBS-9717R-CY7
Descrizione: Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1970R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1970R-HRP
Codice articolo locale: BOSSBS-1970R-HRP
Descrizione: Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
UOM: 1 * 100 µl


Fornitore: Molecular Devices
Descrizione: The FLIPR® Membrane Potential Assay Kit provide a fast, simple and reliable, fluorescence-based assay for detecting changes in voltage across the cell membrane and its homogenous fluorescence-based formulations for observation of real-time membrane potential changes associated with ion channel activation and ion transporter proteins.

Codice catalogo: (BOSSBS-7508R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-7508R-CY5
Codice articolo locale: BOSSBS-7508R-CY5
Descrizione: Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localization: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
UOM: 1 * 100 µl


Codice catalogo: (HT100A-1KT)
Fornitore: SIGMA ALDRICH MICROSCOPY
Codice articolo fornitore: HT100A-1KT
Codice articolo locale: SIAMHT100A-1KT
Descrizione: Silver stain is an aid in distinguishing fungi, basement membrane and opportunistic organisms such as Pneumocystis carinii in tissue sections or smears.
UOM: 1 * 1 KIT


Codice catalogo: (BOSSBS-4901R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-4901R-A680
Codice articolo locale: BOSSBS-4901R-A680
Descrizione: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4901R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-4901R-A555
Codice articolo locale: BOSSBS-4901R-A555
Descrizione: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7647R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-7647R-A555
Codice articolo locale: BOSSBS-7647R-A555
Descrizione: Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1402R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-1402R-A647
Codice articolo locale: BOSSBS-1402R-A647
Descrizione: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1402R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-1402R-A680
Codice articolo locale: BOSSBS-1402R-A680
Descrizione: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5081R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-5081R-CY5
Codice articolo locale: BOSSBS-5081R-CY5
Descrizione: Lamins are nuclear membrane proteins that serve to maintain specific cellular functions, such as DNA replication and chromatin organization. Lamin B receptor (LBR) is an integral protein of the nuclear envelope inner membrane. It is phosphorylated by CDC2 protein kinase in mitosis when the inner nuclear membrane breaks down into vesicles that dissociate from the lamina and the chromatin. It is phosphorylated by different protein kinases in interphase when the membrane is associated with these structures. The cleavage of lamins results in nuclear disregulation and cell death.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4226R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-4226R-CY5.5
Codice articolo locale: BOSSBS-4226R-CY5.5
Descrizione: VAPA is a type IV membrane protein, present in the plasma membrane, intracellular vesicles and may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Two transcript variants encoding distinct isoforms have been identified.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4258R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-4258R-A647
Codice articolo locale: BOSSBS-4258R-A647
Descrizione: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4258R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-4258R-A488
Codice articolo locale: BOSSBS-4258R-A488
Descrizione: General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
UOM: 1 * 100 µl


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