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Image Unavailable-BOSSBS-9717R-CY3

Anti-NID2 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-9717R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-9717R-CY3
Codice articolo locale: BOSSBS-9717R-CY3
Descrizione: Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9717R-A555

Anti-NID2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-9717R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-9717R-A555
Codice articolo locale: BOSSBS-9717R-A555
Descrizione: Nidogens are highly conserved proteins present in vertebrate and invertebrate basement membranes. Nidogens connect the Laminin and Collagen IV networks and integrate other proteins into the membrane. In mammals, two Nidogen proteins, Nidogen and Nidogen-2, interact at comparable levels with Collagen I, IV and Perlecan, serving to stabilize basement membranes and playing a major role in embryogenesis. The two isoforms have a similar shape, consisting of three globular domains, and co-localize in vessel walls and other basement membrane zones. Nidogen-2 is a cell adhesion protein glycosylated at nitrogen and oxygen sites, and is widely distributed in basement membranes in heart, placenta, bone and, to a lesser extent, in pancreas, kidney and skeletal muscle.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1564R-CY3

Anti-Annexin IV Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-1564R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-1564R-CY3
Codice articolo locale: BOSSBS-1564R-CY3
Descrizione: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 (ANXA4) belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59% identity with other members of its family and shares a similar size and exon intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1564R-CY7

Anti-Annexin IV Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-1564R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-1564R-CY7
Codice articolo locale: BOSSBS-1564R-CY7
Descrizione: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 (ANXA4) belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59% identity with other members of its family and shares a similar size and exon intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9744R-HRP

Anti-ANKMY1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-9744R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-9744R-HRP
Codice articolo locale: BOSSBS-9744R-HRP
Descrizione: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions. Three isoforms of ANKMY1 exists due to alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1402R

Anti-SREBP-1/2 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-1402R)
Fornitore: Bioss
Codice articolo fornitore: BS-1402R
Codice articolo locale: BOSSBS-1402R
Descrizione: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1402R-CY3

Anti-SREBP-1/2 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-1402R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-1402R-CY3
Codice articolo locale: BOSSBS-1402R-CY3
Descrizione: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1402R-CY7

Anti-SREBP-1/2 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-1402R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-1402R-CY7
Codice articolo locale: BOSSBS-1402R-CY7
Descrizione: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1402R-FITC

Anti-SREBP-1/2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-1402R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-1402R-FITC
Codice articolo locale: BOSSBS-1402R-FITC
Descrizione: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3'). Has dual sequence specificity binding to both an E-box motif (5'-ATCACGTGA-3') and to SRE-1 (5'-ATCACCCCAC-3'). Isoform SREBP-1A is much more active than isoform SREBP-1C in stimulating transcription from SRE-1-containing promoters. [SUBUNIT] Forms a tight complex with SCAP in the ER membrane. Efficient DNA binding of the soluble transcription factor fragment requires dimerization with another bHLH protein. Interacts with LMNA. [SUBCELLULAR LOCATION] Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols. [SUBCELLULAR LOCATION] Processed sterol regulatory element-binding protein 1: Nucleus. Belongs to the SREBP family.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6072R-A647

Anti-MCC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-6072R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-6072R-A647
Codice articolo locale: BOSSBS-6072R-A647
Descrizione: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13695R-CY3

Anti-PAG1 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-13695R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13695R-CY3
Codice articolo locale: BOSSBS-13695R-CY3
Descrizione: The Src family of protein tyrosine kinases (Src-PTKs) is important in the regulation of growth and differentiation of eukaryotic cells. The activity of Src-PTKs in cells of different types is negatively controlled by Csk. Csk binding protein (Cbp), also designated phosphoprotein associated with glycosphingo-lipid-enriched microdomains (GEMs) or PAG, is a ubiquitously expressed transmembrane phosphoprotein that binds specifically to the SH2 domain of Csk. Cbp is involved in the membrane localization of Csk and in Csk-mediated inhibition of c-Src. In the plasma membrane, Cbp is exclusively localized in the GM1 ganglioside-enriched detergent-insoluble membrane domain, which is important in receptor-mediated signaling. Cbp is a component of the regulatory mechanism controlling the activity of membrane-associated Src-PTKs.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4226R

Anti-VAPA Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-4226R)
Fornitore: Bioss
Codice articolo fornitore: BS-4226R
Codice articolo locale: BOSSBS-4226R
Descrizione: VAPA is a type IV membrane protein, present in the plasma membrane, intracellular vesicles and may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Two transcript variants encoding distinct isoforms have been identified.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6791R

Anti-AIFM3 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-6791R)
Fornitore: Bioss
Codice articolo fornitore: BS-6791R
Codice articolo locale: BOSSBS-6791R
Descrizione: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
UOM: 1 * 100 µl
Product Image-BOSSBS-9187R

Anti-PTPH1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-9187R)
Fornitore: Bioss
Codice articolo fornitore: BS-9187R
Codice articolo locale: BOSSBS-9187R
Descrizione: May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.
UOM: 1 * 100 µl
Product Image-MILFUFC703008

Centrifugal filters, Centricon® Plus-70

Fornitore: Merck
Descrizione: Centrifugal filter units concentrate samples in the range of 15 ml to 70 ml. The large dead stop volume of 350 µl prevents spinning samples to dryness. It has two vertical regenerated cellulose membranes for fast, efficient tangential flow.

Image Unavailable-BOSSBS-2540R-A750

Anti-GLUT12 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-2540R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-2540R-A750
Codice articolo locale: BOSSBS-2540R-A750
Descrizione: GLUT12 belongs to a family of transporters that catalyse the uptake of sugars through facilitated diffusion. Thirteen different types of glucose/fructose transport carrier proteins designated as Glut 1-13 facilitate glucose/fructose transport across the cell membrane. Individual members of the Glut family have predicted secondary structure characteristic of 12 membrane spanning domains of other transport carriers.
UOM: 1 * 100 µl
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