Hai cercato: Magnesium+tetraborate

Codice catalogo: (PRSI79-803)

Fornitore: ProSci Inc.

Codice articolo fornitore: 79-803

Codice articolo locale: PRSI79-803

Descrizione: Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE).

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI27-193)

Fornitore: ProSci Inc.

Codice articolo fornitore: 27-193

Codice articolo locale: PRSI27-193

Descrizione: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

UOM: 1 * 50 µG

Promo

Fornitore: VWR Chemicals

Descrizione: VWR® Trypsin-EDTA solutions are used in cell culture to remove adherent cells from a culture surface. Trypsin is a porcine pancreas-derived enzyme that is commonly used for the dissociation and disaggregation of anchorage-dependent mammalian cells and tissues. The concentration of trypsin necessary to separate cells from their substrate is dependent primarily on the cell type and the age of the culture. EDTA, a chelating agent, enhances enzymatic activity by removing calcium and magnesium ions. These ions obscure the peptide bonds on which trypsin acts as well as enhancing cell to cell adhesion.

MSDS Certificati

Codice catalogo: (PRSI25-607)

Fornitore: ProSci Inc.

Codice articolo fornitore: 25-607

Codice articolo locale: PRSI25-607

Descrizione: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

UOM: 1 * 50 µG

Promo

Codice catalogo: (BOSSBS-6673R)

Fornitore: Bioss

Codice articolo fornitore: BS-6673R

Codice articolo locale: BOSSBS-6673R

Descrizione: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI29-415)

Fornitore: ProSci Inc.

Codice articolo fornitore: 29-415

Codice articolo locale: PRSI29-415

Descrizione: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-6673R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-6673R-HRP

Codice articolo locale: BOSSBS-6673R-HRP

Descrizione: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6673R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-6673R-CY3

Codice articolo locale: BOSSBS-6673R-CY3

Descrizione: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6673R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-6673R-FITC

Codice articolo locale: BOSSBS-6673R-FITC

Descrizione: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6673R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-6673R-CY5.5

Codice articolo locale: BOSSBS-6673R-CY5.5

Descrizione: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5376R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-5376R-A647

Codice articolo locale: BOSSBS-5376R-A647

Descrizione: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5376R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-5376R-A555

Codice articolo locale: BOSSBS-5376R-A555

Descrizione: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5376R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-5376R-CY5.5

Codice articolo locale: BOSSBS-5376R-CY5.5

Descrizione: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5376R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-5376R-A680

Codice articolo locale: BOSSBS-5376R-A680

Descrizione: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI27-910)

Fornitore: ProSci Inc.

Codice articolo fornitore: 27-910

Codice articolo locale: PRSI27-910

Descrizione: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-6673R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-6673R-A680

Codice articolo locale: BOSSBS-6673R-A680

Descrizione: KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterised by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

UOM: 1 * 100 µl

Promo