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Descrizione: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

Codice catalogo: BOSSBS-1373R-A350

UOM: 1 * 100 µl

Codice articolo fornitore: BS-1373R-A350

Codice articolo locale: BOSSBS-1373R-A350

Fornitore: Bioss

Promo

Descrizione: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

Codice catalogo: BOSSBS-1373R-A488

UOM: 1 * 100 µl

Codice articolo fornitore: BS-1373R-A488

Codice articolo locale: BOSSBS-1373R-A488

Fornitore: Bioss

Promo

Descrizione: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.

Codice catalogo: BOSSBS-1373R-A680

UOM: 1 * 100 µl

Codice articolo fornitore: BS-1373R-A680

Codice articolo locale: BOSSBS-1373R-A680

Fornitore: Bioss

Promo

Descrizione: Dibutile ftalato

Codice catalogo: EHERC16171000

UOM: 1 * 0,5 g

Codice articolo fornitore: C16171000

Codice articolo locale: EHERC16171000

Fornitore: EHRENSTORFER

Promo

Descrizione: TRIM36 (tripartite motif-containing 36), also known as RNF98 (RING finger protein 98), HAPRIN (haploid germ cell-specific RBCC protein) or RBCC728, is a 728 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. Predominantly expressed in prostate, testis and brain with weak expression in heart, kidney and lung, TRIM36 contains two B box-type zinc fingers, a SPRY domain, a coiled-coil domain, a fibronectin type-III domain and a RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. Localising to the cytoplasm and the acrosomal region of germ cells and mature sperm, TRIM36 is believed to play a role in the acrosome reaction and fertilisation. In addition, TRIM36 is overexpressed in prostate cancer, suggesting a possible role for TRIM36 in prostate tumorigenesis.

Codice catalogo: BOSSBS-9155R-A680

UOM: 1 * 100 µl

Codice articolo fornitore: BS-9155R-A680

Codice articolo locale: BOSSBS-9155R-A680

Fornitore: Bioss

Promo

Descrizione: TRIM36 (tripartite motif-containing 36), also known as RNF98 (RING finger protein 98), HAPRIN (haploid germ cell-specific RBCC protein) or RBCC728, is a 728 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. Predominantly expressed in prostate, testis and brain with weak expression in heart, kidney and lung, TRIM36 contains two B box-type zinc fingers, a SPRY domain, a coiled-coil domain, a fibronectin type-III domain and a RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. Localizing to the cytoplasm and the acrosomal region of germ cells and mature sperm, TRIM36 is believed to play a role in the acrosome reaction and fertilization. In addition, TRIM36 is overexpressed in prostate cancer, suggesting a possible role for TRIM36 in prostate tumorigenesis.

Codice catalogo: BOSSBS-9155R-A350

UOM: 1 * 100 µl

Codice articolo fornitore: BS-9155R-A350

Codice articolo locale: BOSSBS-9155R-A350

Fornitore: Bioss

Promo

Descrizione: Aluminum acrylate

Codice catalogo: 42003.14

UOM: 1 * 25 g

Codice articolo fornitore: 42003.14

Codice articolo locale: ALFA42003.14

Fornitore: Thermo Fisher Scientific

MSDS Certificati Promo

Descrizione: Aluminum oxalate hydrate ≥99%

Codice catalogo: 44149.18

UOM: 1 * 50 g

Codice articolo fornitore: 44149.18

Codice articolo locale: ALFA44149.18

Fornitore: Thermo Fisher Scientific

MSDS Certificati Promo

Descrizione: 2-Butossietil acetato per sintesi, Sigma-Aldrich®

Codice catalogo: 8.01395.1000

UOM: 1 * 1 L

Codice articolo fornitore: 8.01395.1000

Codice articolo locale: MERC8.01395.1000

Fornitore: Merck

MSDS Promo

Descrizione: Soluble in acetic acid: water (1:1): ≤50 mg/ml, DMF.

Codice catalogo: ICNA0215798283

UOM: 1 * 250 mg

Codice articolo fornitore: 0215798283

Codice articolo locale: ICNA0215798283

Fornitore: MP Biomedicals

Promo

Descrizione: Diisobutyl phthalate

Codice catalogo: EHERC16173500

UOM: 1 * 0,25 g

Codice articolo fornitore: C16173500

Codice articolo locale: EHERC16173500

Fornitore: EHRENSTORFER

Promo

Descrizione: This solution is used for Aluminum determination by the Eriochrome Cyanine R Method.

Codice catalogo: HACH2380123

UOM: 1 * 25 mL

Codice articolo fornitore: 2380123

Codice articolo locale: HACH2380123

Fornitore: Hach

Certificati Promo

Descrizione: Bis(2-etilesile) ftalato

Codice catalogo: PROOCHE144

UOM: 1 * 1 g

Codice articolo fornitore: CHE144

Codice articolo locale: PROOCHE144

Fornitore: LGC Standards PROMOCHEM

Promo

Descrizione: Dibutil sebacato

Codice catalogo: PROOMM0925.00

UOM: 1 * 500 mg

Codice articolo fornitore: MM0925.00

Codice articolo locale: PROOMM0925.00

Fornitore: LGC Standards PROMOCHEM

Promo

Descrizione: Bis(2-ethylhexyl)maleate

Codice catalogo: EHERC14727000

UOM: 1 * 250 mg

Codice articolo fornitore: C14727000

Codice articolo locale: EHERC14727000

Fornitore: EHRENSTORFER

Promo

Descrizione: Chelex beads are made of a styrene divinylbenzene copolymer containing paired iminodiacetate ions, which act as chelating groups in binding polyvalent metal ions.

Codice catalogo: GENOBTNM-0024

UOM: 1 * 10 mL

Codice articolo fornitore: BTNM-0024

Codice articolo locale: GENOBTNM-0024

Fornitore: G-Biosciences

Promo