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Codice catalogo: (BOSSBS-4670R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-4670R-A555
Codice articolo locale: BOSSBS-4670R-A555
Descrizione: Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5065R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-5065R-HRP
Codice articolo locale: BOSSBS-5065R-HRP
Descrizione: The HADHB gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found; however, their full-length nature is not known.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9010R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-9010R-CY3
Codice articolo locale: BOSSBS-9010R-CY3
Descrizione: DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7838R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-7838R-A750
Codice articolo locale: BOSSBS-7838R-A750
Descrizione: May function as an adapter linking the Par3 complex to the GPSM1/GPSM2 complex. Involved in spindle orientation during mitosis it may regulate cell proliferation and differentiation in the developing nervous system. May play a role in the asymmetric division of fibroblasts and participate in the process of stratification of the squamous epithelium.Tissue specificity:Isoform 1 is expressed in various tissues with stronger expression in liver, kidney and small intestine. Isoform 2 is abundantly expressed in small intestine and to a lower extent in lung and pancreas.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4670R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-4670R-FITC
Codice articolo locale: BOSSBS-4670R-FITC
Descrizione: Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4670R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-4670R-A680
Codice articolo locale: BOSSBS-4670R-A680
Descrizione: Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-8040R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-8040R-A750
Codice articolo locale: BOSSBS-8040R-A750
Descrizione: The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4670R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-4670R-CY5
Codice articolo locale: BOSSBS-4670R-CY5
Descrizione: Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7865R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-7865R-CY5
Codice articolo locale: BOSSBS-7865R-CY5
Descrizione: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7865R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-7865R-CY5.5
Codice articolo locale: BOSSBS-7865R-CY5.5
Descrizione: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7865R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7865R-FITC
Codice articolo locale: BOSSBS-7865R-FITC
Descrizione: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4670R)
Fornitore: Bioss
Codice articolo fornitore: BS-4670R
Codice articolo locale: BOSSBS-4670R
Descrizione: Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.
UOM: 1 * 100 µl


Fornitore: Merck
Descrizione: La colonna ZIC®-cHILIC è basata sulla stessa tecnologia della ZIC®-HILIC, ma con un gruppo funzionale differente e una procedura di produzione migliorata. L’orientamento di carica differente del gruppo funzionale zwitterionico porta a una selettività diversa, e complementare, per i composti idrofili polari. La selettività è particolarmente vantaggiosa per i composti idrofili con carica negativa e positiva, zwitterionici o neutri, come ad esempio acidi organici, amminoacidi, metaboliti, amminoglicosidi e nucleotidi.
Fornitore: Biotium
Descrizione: This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. The yolk sac and the liver produce AFP during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spinal bifida and anencephaly.

Codice catalogo: (BOSSBS-4708R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-4708R-A350
Codice articolo locale: BOSSBS-4708R-A350
Descrizione: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4708R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-4708R-A647
Codice articolo locale: BOSSBS-4708R-A647
Descrizione: Alpha 1 Fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Expression has been documented in human adrenal, liver, ovary, testis, and pancreas. ESTs have been isolated from normal human brain, liver/spleen, embryo and uterus tissue libraries.
UOM: 1 * 100 µl


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