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Product Image-ENZOALX420033M005

HAT activator, CTPB ≥97% (by 1H-NMR)

Fornitore: ENZO LIFE SCIENCES AG
Descrizione: p300 HAT activator.

New Product

Image Unavailable-ENZOALX850326KI01

HAT activity assay kit

Codice catalogo: (ENZOALX850326KI01)
Fornitore: ENZO LIFE SCIENCES AG
Codice articolo fornitore: ALX850326KI01
Codice articolo locale: ENZOALX850326KI01
Descrizione: Histone acetyltransferases (HATs) have been implicated to play a crucial role in various cellular functions, such as gene transcription, differentiation, and proliferation. HAT Activity Colorimetric Assay Kit offers a convenient, nonradioactive system for a rapid and sensitive detection of HAT activity in mammalian samples.
UOM: 1 * 100 Tests

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Image Unavailable-BOSSBS-13686R-A488

Anti-KAT5 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-13686R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-13686R-A488
Codice articolo locale: BOSSBS-13686R-A488
Descrizione: MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13686R-CY3

Anti-KAT5 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-13686R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-13686R-CY3
Codice articolo locale: BOSSBS-13686R-CY3
Descrizione: MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13686R-A647

Anti-KAT5 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-13686R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-13686R-A647
Codice articolo locale: BOSSBS-13686R-A647
Descrizione: MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13686R-FITC

Anti-KAT5 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-13686R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13686R-FITC
Codice articolo locale: BOSSBS-13686R-FITC
Descrizione: MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8611R-CY5

Anti-USP22 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-8611R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-8611R-CY5
Codice articolo locale: BOSSBS-8611R-CY5
Descrizione: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5272R-CY5

Anti-MORF4L1 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-5272R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-5272R-CY5
Codice articolo locale: BOSSBS-5272R-CY5
Descrizione: MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5272R-FITC

Anti-MORF4L1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-5272R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-5272R-FITC
Codice articolo locale: BOSSBS-5272R-FITC
Descrizione: MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5272R-A555

Anti-MORF4L1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-5272R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-5272R-A555
Codice articolo locale: BOSSBS-5272R-A555
Descrizione: MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8611R-CY7

Anti-USP22 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-8611R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-8611R-CY7
Codice articolo locale: BOSSBS-8611R-CY7
Descrizione: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8611R-A350

Anti-USP22 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-8611R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-8611R-A350
Codice articolo locale: BOSSBS-8611R-A350
Descrizione: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8611R-HRP

Anti-USP22 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-8611R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-8611R-HRP
Codice articolo locale: BOSSBS-8611R-HRP
Descrizione: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8611R-FITC

Anti-USP22 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-8611R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-8611R-FITC
Codice articolo locale: BOSSBS-8611R-FITC
Descrizione: Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13686R

Anti-KAT5 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-13686R)
Fornitore: Bioss
Codice articolo fornitore: BS-13686R
Codice articolo locale: BOSSBS-13686R
Descrizione: MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13686R-CY5

Anti-KAT5 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-13686R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-13686R-CY5
Codice articolo locale: BOSSBS-13686R-CY5
Descrizione: MOZ (monocytic leukemia zinc finger protein) is a chromatin-associated histone acetyltransferase (HAT) that regulates chromatin remodeling and transcription. The MOZ gene was initially isolated as a consequence of two variant translocations that were identified in a distinct subtype of acute myeloid leukemias and resulted in the formation of MOZ fusion proteins. These fusions involve the HAT domain of MOZ with the activation domain of either transcriptional coactivator protein TIF2/GRIP1 or CBP, and lead to enhanced transcriptional activation by a mechanism involving aberrant histone acetylation. Additional MOZ related proteins, including MORF (MOZ related factor) and TIP60 (TAT interacting proteins 60), share significant similarities with MOZ including the putuative HAT domain. MORF also contains a strong transcriptional repression domain at its N terminus and a highly potent activation domain at the C terminus, suggesting that MORF has both HAT activity and contributes to the regulation of transcriptional activation. TIP60 was originally identified as a coactivator for the HIV TAT protein and also functions as a nuclear hormone receptor coactivator that enhances ligand dependent steroid receptor-mediated transactivation involving the androgen, estrogen and progesterone receptors.
UOM: 1 * 100 µl
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