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Codice catalogo: (BOSSBS-2675R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-2675R-A350
Codice articolo locale: BOSSBS-2675R-A350
Descrizione: a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2675R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-2675R-FITC
Codice articolo locale: BOSSBS-2675R-FITC
Descrizione: a-Fodrin is a universally expressed membrane associated cytoskeletal protein consisting of alpha and beta subunits. The protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha Fodrin is one of the important targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases generating N terminal 150 kDa, C terminal 120 kDa, and 35 kDa major products. Cleavage of alpha Fodrin leads to membrane malfunction and cell shrinkage.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9712R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-9712R-CY3
Codice articolo locale: BOSSBS-9712R-CY3
Descrizione: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-10427R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-10427R-A488
Codice articolo locale: BOSSBS-10427R-A488
Descrizione: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-10427R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-10427R-CY3
Codice articolo locale: BOSSBS-10427R-CY3
Descrizione: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-10427R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-10427R-CY5
Codice articolo locale: BOSSBS-10427R-CY5
Descrizione: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7097R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-7097R-A350
Codice articolo locale: BOSSBS-7097R-A350
Descrizione: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7097R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7097R-FITC
Codice articolo locale: BOSSBS-7097R-FITC
Descrizione: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7097R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-7097R-A555
Codice articolo locale: BOSSBS-7097R-A555
Descrizione: May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11841R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11841R-CY3
Codice articolo locale: BOSSBS-11841R-CY3
Descrizione: TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6168R)
Fornitore: Bioss
Codice articolo fornitore: BS-6168R
Codice articolo locale: BOSSBS-6168R
Descrizione: RAB proteins, like RAB8B, are low molecular mass monomeric GTPases that localize on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB proteins function in intracellular vesicle transport by aiding in the docking and/or fusion of vesicles with their target membranes
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7508R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-7508R-CY3
Codice articolo locale: BOSSBS-7508R-CY3
Descrizione: Tmtsp is a novel marker gene for primitive hematopoietic cells and endothelial cells. Tmtsp gene is a newly identified cell-surface molecule with thrombospondin domain. Tmtsp antibody would serve as a valuable tool for the analysis of both embryonic and adult hematopoiesis, as well as for vascular biology.Cellular localization: Isoform 1: Membrane; Single-pass type I membrane protein, Isoform 2: Membrane; Single-pass type I membrane protein, Isoform 3: Secreted.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9712R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-9712R-A647
Codice articolo locale: BOSSBS-9712R-A647
Descrizione: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-9712R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-9712R-FITC
Codice articolo locale: BOSSBS-9712R-FITC
Descrizione: Na+/H+ exchangers (NHEs) catalyze the transport of Na+ in exchange for H+ across membranes in organisms and are required for numerous physiological processes. NHEDC2 (Na+/H+ exchanger-like domain-containing protein 2), also known as NHA2, is a 537 amino acid mitochondrial protein. NHEDC2 is involved in organelle volume homeostasis by catalyzing the exchange of protons for Na+ and Li+ across the inner mitochondrial membrane. Found in red blood cells, NHEDC2 is required for bone resorption activity and osteoclast differentiation. As a multi-pass membrane protein, NHEDC2 is expressed as two isoforms produced by alternative splicing events.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11352R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-11352R-CY5
Codice articolo locale: BOSSBS-11352R-CY5
Descrizione: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11067R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11067R-A647
Codice articolo locale: BOSSBS-11067R-A647
Descrizione: Beta-tectorin is a 329 amino acid secreted protein that contains one zona pellucida (ZP) domain. While it may form homomeric filaments after self-association, Beta-tectorin may also form heteromeric filaments when it associates with ?tectorin. The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the apical surface of the inner ear epithelia and proteolytically released into the extracellular compartment. Beta-tectorin is one of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.
UOM: 1 * 100 µl


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