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Fornitore: TCI EUROPE
Descrizione: Fluorescein chloride ≥95.0% (by HPLC) reagent for amines

Codice catalogo: (BOSSBS-12159R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-12159R-FITC
Codice articolo locale: BOSSBS-12159R-FITC
Descrizione: May act as a calcium-activated chloride channel.
UOM: 1 * 100 µl


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Codice catalogo: (BOSSBS-6787R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-6787R-FITC
Codice articolo locale: BOSSBS-6787R-FITC
Descrizione: Sodium-independent transporter of chloride and iodide.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12061R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-12061R-FITC
Codice articolo locale: BOSSBS-12061R-FITC
Descrizione: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-7694R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-7694R-FITC
Codice articolo locale: BOSSBS-7694R-FITC
Descrizione: Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3794R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-3794R-FITC
Codice articolo locale: BOSSBS-3794R-FITC
Descrizione: Calcium-activated chloride channel (CaCC) which plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12084R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-12084R-FITC
Codice articolo locale: BOSSBS-12084R-FITC
Descrizione: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3766R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-3766R-FITC
Codice articolo locale: BOSSBS-3766R-FITC
Descrizione: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-13629R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-13629R-FITC
Codice articolo locale: BOSSBS-13629R-FITC
Descrizione: Chloride channels (CLCs) regulate cellular traffic of chloride ions, a critical component of all living cells. CLCs are involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. The putative 247 amino acid protein chloride intracellular channel 2 (CLIC2), also designated XAP121, shares 60% identity with the CLIC1 protein and demonstrates expression in only fetal liver and adult skeletal muscle tissues. The CLIC2 gene maps to chromosome Xq28 and contains 6 exons. Because a direct association exists between a number of human chloride channel genes and a range of hereditary diseases, CLIC2 is a potential candidate for one of the many diseases linked to Xq28. The hereditary form of incontinentia pigmenti (IP2), for example, is a rare disorder characterized by abnormalities of the tissues and organs derived from the ectoderm and neuroectoderm that has been linked to Xq28
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-4112R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-4112R-FITC
Codice articolo locale: BOSSBS-4112R-FITC
Descrizione: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3604R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-3604R-FITC
Codice articolo locale: BOSSBS-3604R-FITC
Descrizione: WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6981R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-6981R-FITC
Codice articolo locale: BOSSBS-6981R-FITC
Descrizione: Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1232R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-1232R-FITC
Codice articolo locale: BOSSBS-1232R-FITC
Descrizione: Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1945R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-1945R-FITC
Codice articolo locale: BOSSBS-1945R-FITC
Descrizione: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Phosphorylates WNK4. Regulates the phosphorylation of SLC12A1 and SLC12A2. Increases Ca(2+) influx mediated by TRPV5 and TRPV6 by enhancing their membrane expression level via a kinase-dependent pathway. Inhibits the activity of KCNJ1 by decreasing its expression at the cell membrane in a non-catalytic manner. Isoform 1, isoform 2, isoform 3 and isoform 4 stimulate the activity of SLC12A1, SLC12A2 and SLC12A3 and inhibit the activity of SLC12A4, SLC12A5, SLC12A6 and SLC12A7. According to PubMed:19470686, isoform 1 inhibits the activity of SLC12A3.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-1247R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-1247R-FITC
Codice articolo locale: BOSSBS-1247R-FITC
Descrizione: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3395R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-3395R-FITC
Codice articolo locale: BOSSBS-3395R-FITC
Descrizione: This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
UOM: 1 * 100 µl


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