Hai cercato: Doxorubicin+hydrochloride

Codice catalogo: (PHR1789-200MG)

Fornitore: Merck

Codice articolo fornitore: PHR1789-200MG

Codice articolo locale: SUPLPHR1789-200MG

Descrizione: Organic Standard, Doxorubicin Hydrochloride

UOM: 1 * 200 mg

Promo

Fornitore: TCI

Descrizione: Doxorubicin hydrochloride ≥95.0% (by HPLC)

Certificati

Fornitore: Apollo Scientific

Descrizione: Inhibitor of RNA synthesis.

Fornitore: ENZO LIFE SCIENCES

Descrizione: Topoisomerase inhibitor

New Product

Codice catalogo: (1225703.)

Fornitore: USP

Codice articolo fornitore: 1225703

Codice articolo locale: USPH1225703

Descrizione: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.

UOM: 1 * 50 mg

Promo

Codice catalogo: (ICNA0215910110)

Fornitore: MP Biomedicals

Codice articolo fornitore: 0215910110

Codice articolo locale: ICNA0215910110

Descrizione: Doxorubicin Hydrochloride is a chemotherapeutic, antitumour, immunosuppressive, and antibiotic agent.

UOM: 1 * 10 mg

MSDS Promo

Fornitore: Cayman Chemical

Descrizione: Doxorubicin is an anthracycline anti-tumour antibiotic which involves in inhibition of DNA topoisomerase II by inducing double-stranded DNA breaks. It is also involved in the inhibition of nucleic acid synthesis by intercalating within DNA. The accumulation of the p53 tumour suppressor protein leads to the apoptosis in cells.

Codice catalogo: (PROOBP990)

Fornitore: LGC Standards PROMOCHEM

Codice articolo fornitore: BP990

Codice articolo locale: PROOBP990

Descrizione: Organic Standard, Doxorubicin hydrochloride assay standard

UOM: 1 * 100 mg

Promo

Fornitore: Thermo Scientific

Descrizione: Doxorubicin hydrochloride is an anti-tumour, anti-neoplastic and anti-biotic agent that inhibits DNA topoisomerase II. It also inhibits nucleic acid synthesis and induces apoptosis.

MSDS Certificati

Codice catalogo: (API-05)

Fornitore: G-Biosciences

Codice articolo fornitore: API-05

Codice articolo locale: GENOAPI-05

Descrizione: Apoptosis is commonly defined as programmed mechanism of cell death and is a highly regulated process that can be initiated by a variety of internal and external stimuli (inducers).

UOM: 1 * 50 µl

Promo

Codice catalogo: (BOSSBS-3523R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-3523R-HRP

Codice articolo locale: BOSSBS-3523R-HRP

Descrizione: Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

UOM: 1 * 100 µl

Promo

Codice catalogo: (API-16S)

Fornitore: G-Biosciences

Codice articolo fornitore: API-16S

Codice articolo locale: GENOAPI-16S

Descrizione: Apoptosis inducers are used for induction of apoptosis in cultured cells. The selection of apoptosis inducers include actinomycin D, camptothecin, cycloheximide, dexamethasone, doxorubicin and etoposide.

UOM: 1 * 1 SET

Promo

Codice catalogo: (BOSSBS-7953R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-7953R-HRP

Codice articolo locale: BOSSBS-7953R-HRP

Descrizione: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-7953R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-7953R-A680

Codice articolo locale: BOSSBS-7953R-A680

Descrizione: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-7953R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-7953R-A750

Codice articolo locale: BOSSBS-7953R-A750

Descrizione: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI5815)

Fornitore: ProSci Inc.

Codice articolo fornitore: 5815

Codice articolo locale: PRSI5815

Descrizione: FOXO4 Antibody: FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In the absence of PI3K/AKT activation, FOXO4 localizes in the nucleus where it functions as a transcription factor. FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS), resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS. It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity.

UOM: 1 * 100 µG

Promo