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Image Unavailable-BOSSBS-11696R-A647

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-11696R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-A647
Codice articolo locale: BOSSBS-11696R-A647
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-A555

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-11696R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-A555
Codice articolo locale: BOSSBS-11696R-A555
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-CY5

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-11696R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-CY5
Codice articolo locale: BOSSBS-11696R-CY5
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-A750

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-11696R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-A750
Codice articolo locale: BOSSBS-11696R-A750
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin's disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-A680

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-11696R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-A680
Codice articolo locale: BOSSBS-11696R-A680
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin's disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-HRP

Anti-HAP40/F8a Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-11696R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-HRP
Codice articolo locale: BOSSBS-11696R-HRP
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-A350

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-11696R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-A350
Codice articolo locale: BOSSBS-11696R-A350
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-FITC

Anti-HAP40/F8a Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-11696R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-11696R-FITC
Codice articolo locale: BOSSBS-11696R-FITC
Descrizione: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BIRBORB24956-1

Anti-Glyceraldehyde-3-PDH Mouse monoclonal antibody

Codice catalogo: (BIRBORB24956-1)
Fornitore: Biorbyt
Codice articolo fornitore: ORB24956-1
Codice articolo locale: BIRBORB24956-1
Descrizione: Anti-Glyceraldehyde-3-PDH Mouse Monoclonal Antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24832-1

Anti-glyceraldehyde-3-PDH Mouse monoclonal antibody

Codice catalogo: (BIRBORB24832-1)
Fornitore: Biorbyt
Codice articolo fornitore: ORB24832-1
Codice articolo locale: BIRBORB24832-1
Descrizione: Anti-glyceraldehyde-3-PDH Mouse Monoclonal Antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24957-1

Anti-glyceraldehyde-3-PDH Mouse Monoclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BIRBORB24957-1)
Fornitore: Biorbyt
Codice articolo fornitore: ORB24957-1
Codice articolo locale: BIRBORB24957-1
Descrizione: Anti-glyceraldehyde-3-PDH Mouse Monoclonal Antibody (HRP (Horseradish Peroxidase))
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24987-1

Anti-Glyceraldehyde-3-PDH Mouse monoclonal antibody

Codice catalogo: (BIRBORB24987-1)
Fornitore: Biorbyt
Codice articolo fornitore: ORB24987-1
Codice articolo locale: BIRBORB24987-1
Descrizione: Anti-Glyceraldehyde-3-PDH Mouse Monoclonal Antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Image Unavailable-BIRBORB24837-1

Anti-glyceraldehyde-3-PDH Mouse monoclonal antibody

Codice catalogo: (BIRBORB24837-1)
Fornitore: Biorbyt
Codice articolo fornitore: ORB24837-1
Codice articolo locale: BIRBORB24837-1
Descrizione: Anti-glyceraldehyde-3-PDH Mouse Monoclonal Antibody
UOM: 1 * 1 mg

Market Source Item This is a MarketSource item. Additional charges may apply

Product Image-PRSI30-388

Anti-ALDOC Rabbit Polyclonal Antibody

Codice catalogo: (PRSI30-388)
Fornitore: ProSci Inc.
Codice articolo fornitore: 30-388
Codice articolo locale: PRSI30-388
Descrizione: ALDOC gene is a member of the class I fructose-biphosphate aldolase gene family. ALDOC is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
UOM: 1 * 50 µG
Image Unavailable-PRSI92-622

E. coli recombinant tryptophan synthase alpha chain (from E. coli)

Codice catalogo: (PRSI92-622)
Fornitore: ProSci Inc.
Codice articolo fornitore: 92-622
Codice articolo locale: PRSI92-622
Descrizione: Tryptophan synthase is an enzyme that catalyses the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as humans. Tryptophan synthase typically exists as an alpha- beta beta - alpha complex.The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H₂O.The beta subunits catalyse the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.
UOM: 1 * 50 µG
Image Unavailable-PRSI92-623

E. coli recombinant tryptophan synthase beta chain (from E. coli)

Codice catalogo: (PRSI92-623)
Fornitore: ProSci Inc.
Codice articolo fornitore: 92-623
Codice articolo locale: PRSI92-623
Descrizione: Tryptophan synthase is an enzyme that catalyses the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from animals such as humans. Tryptophan synthase typically exists as an alpha- beta beta - alpha complex.The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate: L-serine + 1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H₂O.The beta subunits catalyse the irreversible condensation of indole and serine to form tryptophan in a pyridoxal phosphate (PLP) dependent reaction. Their assembly into a complex leads to structural changes in both subunits resulting in reciprocal activation.
UOM: 1 * 50 µG
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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