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Codice catalogo: (BOSSBS-11561R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-11561R-A750
Codice articolo locale: BOSSBS-11561R-A750
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterised by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene. SMN, also known as Gemin1, SMN1, SMNT and BCD541, exists as four isoforms produced by alternative splicing. SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies). Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, and nuclear SMN mediates recycling of pre-mRNA splicing factors. Nearly identical telomeric and centromeric forms of SMN encode the same protein; however, only mutations in the telomeric form are associated with the disease-state SMA. SMN is expressed in a wide variety of tissues including brain, kidney, liver, spinal cord and moderately in skeletal and cardiac muscle.
UOM: 1 * 100 µl


Codice catalogo: (ABNOMAB6267)
Fornitore: Abnova
Codice articolo fornitore: MAB6267
Codice articolo locale: ABNOMAB6267
Descrizione: Mouse monoclonal antibody raised against recombinant CSF2.
UOM: 1 * 500 µG


Codice catalogo: (BOSSBS-11562R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-A350
Codice articolo locale: BOSSBS-11562R-A350
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11562R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-HRP
Codice articolo locale: BOSSBS-11562R-HRP
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (ORIGCF807073)
Fornitore: OriGene
Codice articolo fornitore: CF807073
Codice articolo locale: ORIGCF807073
Descrizione: Anti-LAG3 Mouse Monoclonal Antibody [clone: OTI5C3 (formerly 5C3)]
UOM: 1 * 100 µl


Codice catalogo: (ORIGTA183017)
Fornitore: OriGene
Codice articolo fornitore: TA183017
Codice articolo locale: ORIGTA183017
Descrizione: Recommended Dilutions: Western Blot: 1:1000-5000
UOM: 1 * 100 µl


Codice catalogo: (ORIGTA183044)
Fornitore: OriGene
Codice articolo fornitore: TA183044
Codice articolo locale: ORIGTA183044
Descrizione: Anti-Dendra2 IgG2b Monoclonal Antibody (Magnetic beads) [clone: OTI1G6 (formerly 1G6)]
UOM: 1 * 1 mL


Codice catalogo: (ORIGTA183025)
Fornitore: OriGene
Codice articolo fornitore: TA183025
Codice articolo locale: ORIGTA183025
Descrizione: Anti-DsRed2 IgG2b Monoclonal Antibody (Magnetic beads) [clone: OTI1B11 (formerly 1B11)]
UOM: 1 * 1 mL


Codice catalogo: (ORIGTA183026)
Fornitore: OriGene
Codice articolo fornitore: TA183026
Codice articolo locale: ORIGTA183026
Descrizione: Anti-Timer IgG1 Monoclonal Antibody (Magnetic beads) [clone: OTI3C9 (formerly 3C9)]
UOM: 1 * 1 mL


Codice catalogo: (ORIGTA183032)
Fornitore: OriGene
Codice articolo fornitore: TA183032
Codice articolo locale: ORIGTA183032
Descrizione: Anti-mBanana IgG1 Monoclonal Antibody (Magnetic beads) [clone: OTI2E5 (formerly 2E5)]
UOM: 1 * 1 mL


Codice catalogo: (BOSSBS-11562R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-CY3
Codice articolo locale: BOSSBS-11562R-CY3
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11562R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-CY7
Codice articolo locale: BOSSBS-11562R-CY7
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11562R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-FITC
Codice articolo locale: BOSSBS-11562R-FITC
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11562R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-CY5
Codice articolo locale: BOSSBS-11562R-CY5
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (ORIGTA183013)
Fornitore: OriGene
Codice articolo fornitore: TA183013
Codice articolo locale: ORIGTA183013
Descrizione: Recommended Dilutions: Western Blot: 1:1000-5000
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11561R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11561R-A680
Codice articolo locale: BOSSBS-11561R-A680
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterised by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene. SMN, also known as Gemin1, SMN1, SMNT and BCD541, exists as four isoforms produced by alternative splicing. SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies). Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, and nuclear SMN mediates recycling of pre-mRNA splicing factors. Nearly identical telomeric and centromeric forms of SMN encode the same protein; however, only mutations in the telomeric form are associated with the disease-state SMA. SMN is expressed in a wide variety of tissues including brain, kidney, liver, spinal cord and moderately in skeletal and cardiac muscle.
UOM: 1 * 100 µl


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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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