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Codice catalogo: (BOSSBS-12173R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-12173R-CY7
Codice articolo locale: BOSSBS-12173R-CY7
Descrizione: KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11562R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-A350
Codice articolo locale: BOSSBS-11562R-A350
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11562R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-11562R-HRP
Codice articolo locale: BOSSBS-11562R-HRP
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene. Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. It is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies). The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5. Gemin2 is expressed in spinal cord. It can be induced by TGF∫ treatment and expression is high in several E-cadherin negative human carcinoma cell lines. SMN is expressed in a wide variety of tissues including brain, kidney, liver and spinal cord, and moderately in skeletal and cardiac muscle. The gene encoding Gemin2 maps to human chromosome 14q13.
UOM: 1 * 100 µl


Codice catalogo: (ORIGTA183031)
Fornitore: OriGene
Codice articolo fornitore: TA183031
Codice articolo locale: ORIGTA183031
Descrizione: Anti-mRaspberry IgG1 Monoclonal Antibody (Magnetic beads) [clone: OTI2A6 (formerly 2A6)]
UOM: 1 * 1 mL


Codice catalogo: (ORIGTA183042)
Fornitore: OriGene
Codice articolo fornitore: TA183042
Codice articolo locale: ORIGTA183042
Descrizione: Anti-mBFP IgG1 Monoclonal Antibody (Magnetic beads) [clone: OTI2E7 (formerly 2E7)]
UOM: 1 * 1 mL


Codice catalogo: (ABCAAB20719-500)
Fornitore: Abcam
Codice articolo fornitore: AB20719-500
Codice articolo locale: ABCAAB20719-500
Descrizione: Anti-Treponema pallidum Rabbit Polyclonal Antibody [clone: ] (FITC)
UOM: 1 * 500 µl


Codice catalogo: (ORIGTA183019)
Fornitore: OriGene
Codice articolo fornitore: TA183019
Codice articolo locale: ORIGTA183019
Descrizione: Recommended Dilutions: Western Blot: 1:1000-5000
UOM: 1 * 100 µl


Codice catalogo: (ORIGTA183022)
Fornitore: OriGene
Codice articolo fornitore: TA183022
Codice articolo locale: ORIGTA183022
Descrizione: Recommended Dilutions: Western Blot: 1:1000-5000
UOM: 1 * 100 µl


Codice catalogo: (ORIGTA183029)
Fornitore: OriGene
Codice articolo fornitore: TA183029
Codice articolo locale: ORIGTA183029
Descrizione: Anti-DsRed-Express2 IgG2b Monoclonal Antibody (Magnetic beads) [clone: OTI1C4 (formerly 1C4)]
UOM: 1 * 1 mL


Codice catalogo: (ORIGTA183003)
Fornitore: OriGene
Codice articolo fornitore: TA183003
Codice articolo locale: ORIGTA183003
Descrizione: Recommended Dilutions: Western Blot: 1:1000-5000
UOM: 1 * 100 µl


Codice catalogo: (ORIGTA183041)
Fornitore: OriGene
Codice articolo fornitore: TA183041
Codice articolo locale: ORIGTA183041
Descrizione: Anti-mKate IgG1 Monoclonal Antibody (Magnetic beads) [clone: OTI1G5 (formerly 1G5)]
UOM: 1 * 1 mL


Codice catalogo: (ORIGTA183037)
Fornitore: OriGene
Codice articolo fornitore: TA183037
Codice articolo locale: ORIGTA183037
Descrizione: Anti-mPlum IgG1 Monoclonal Antibody (Magnetic beads) [clone: OTI2G4 (formerly 2G4)]
UOM: 1 * 1 mL


Codice catalogo: (ORIGCF807146)
Fornitore: OriGene
Codice articolo fornitore: CF807146
Codice articolo locale: ORIGCF807146
Descrizione: Anti-LAG3 Mouse Monoclonal Antibody [clone: OTI10E7 (formerly 10E7)]
UOM: 1 * 100 µG


Codice catalogo: (ENZOADI905800100)
Fornitore: ENZO LIFE SCIENCES
Codice articolo fornitore: ADI905800100
Codice articolo locale: ENZOADI905800100
Descrizione: The conversion of arachidonic acid to prostaglandin H2 (PGH2) by cyclooxygenase (COX) enzymes is the first step in the synthesis of prostanoids. Prostaglandin D2 (PGD2) is synthesized from PGH2 by the action of PGD synthase, and its actions in vasodilation and platelet activation are mediated via activation of two identified G-protein coupled receptors (GPCRs): DP1 and DP2 (formerly CRTH2). Both DP1 and DP2 receptors are coupled to Gs alpha subunits, resulting in increased adenylyl cyclase activity and cAMP production upon agonist binding. DP1 receptor is expressed moderately in the ileum and weakly in the lung, stomach, and uterus of mice, and weakly in the small intestine of humans. In rodents, expression of PGD synthase and the DP1 receptor is seen in the leptomeninges, where it is believed they play a role in the induction of sleep. The DP1 receptor may also oppose DP2-mediated activation of basophils, eosinophils, and Th2 cells.
UOM: 1 * 100 µG


Codice catalogo: (BOSSBS-11561R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-11561R-A680
Codice articolo locale: BOSSBS-11561R-A680
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterised by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene. SMN, also known as Gemin1, SMN1, SMNT and BCD541, exists as four isoforms produced by alternative splicing. SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies). Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, and nuclear SMN mediates recycling of pre-mRNA splicing factors. Nearly identical telomeric and centromeric forms of SMN encode the same protein; however, only mutations in the telomeric form are associated with the disease-state SMA. SMN is expressed in a wide variety of tissues including brain, kidney, liver, spinal cord and moderately in skeletal and cardiac muscle.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-11561R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-11561R-A488
Codice articolo locale: BOSSBS-11561R-A488
Descrizione: Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations of SMN (survival of motor neuron) gene. SMN, also known as Gemin1, SMN1, SMNT and BCD541, exists as four isoforms produced by alternative splicing. SMN is oligomeric and forms a complex with Gemin2 (formerly SIP1), Gemin3 (a DEAD box RNA helicase), Gemin4, Gemin5 and Gemin6, as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (gemini of the coiled bodies). Cytoplasmic SMN interacts with spliceosomal Sm proteins and facilitates their assembly onto U snRNAs, and nuclear SMN mediates recycling of pre-mRNA splicing factors. Nearly identical telomeric and centromeric forms of SMN encode the same protein; however, only mutations in the telomeric form are associated with the disease-state SMA. SMN is expresed in a wide variety of tissues including brain, kidney, liver, spinal cord and moderately in skeletal and cardiac muscle.
UOM: 1 * 100 µl


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