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Anti-CYP7B1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-5052R)
Fornitore: Bioss
Codice articolo fornitore: BS-5052R
Codice articolo locale: BOSSBS-5052R
Descrizione: The CYP7B1 protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme is likely to play a minor role in total bile acid synthesis, and may also be involved in the development of neurosteroid metabolism, atherosclerosis and sex hormone synthesis, and is a member of the cytochrome P450 superfamily of enzymes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1972R-A750

Anti-LCAT Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-1972R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-1972R-A750
Codice articolo locale: BOSSBS-1972R-A750
Descrizione: Central enzyme in the extracellular metabolism of plasma lipoproteins. synthesised mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodelling high-density lipoprotein particles into their spherical forms.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-A680

Anti-CYP39A1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-5050R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-5050R-A680
Codice articolo locale: BOSSBS-5050R-A680
Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-A647

Anti-CYP39A1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-5050R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-5050R-A647
Codice articolo locale: BOSSBS-5050R-A647
Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3694R-A680

Anti-CETP Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-3694R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-3694R-A680
Codice articolo locale: BOSSBS-3694R-A680
Descrizione: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-A488

Anti-CYP39A1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-5050R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-5050R-A488
Codice articolo locale: BOSSBS-5050R-A488
Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-A350

Anti-CYP39A1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-5050R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-5050R-A350
Codice articolo locale: BOSSBS-5050R-A350
Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6480R-A750

Anti-CH25H Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-6480R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-6480R-A750
Codice articolo locale: BOSSBS-6480R-A750
Descrizione: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesising a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6480R-CY5.5

Anti-CH25H Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-6480R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-6480R-CY5.5
Codice articolo locale: BOSSBS-6480R-CY5.5
Descrizione: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12324R-A350

Anti-PTCHD2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Codice catalogo: (BOSSBS-12324R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-12324R-A350
Codice articolo locale: BOSSBS-12324R-A350
Descrizione: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R

Anti-CYP39A1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-5050R)
Fornitore: Bioss
Codice articolo fornitore: BS-5050R
Codice articolo locale: BOSSBS-5050R
Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5050R-CY5

Anti-CYP39A1 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-5050R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-5050R-CY5
Codice articolo locale: BOSSBS-5050R-CY5
Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12501R-A488

Anti-APOM Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-12501R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-12501R-A488
Codice articolo locale: BOSSBS-12501R-A488
Descrizione: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6560R-HRP

Anti-OSBP2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Codice catalogo: (BOSSBS-6560R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-6560R-HRP
Codice articolo locale: BOSSBS-6560R-HRP
Descrizione: The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6560R-A680

Anti-OSBP2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Codice catalogo: (BOSSBS-6560R-A680)
Fornitore: Bioss
Codice articolo fornitore: BS-6560R-A680
Codice articolo locale: BOSSBS-6560R-A680
Descrizione: The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localises to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6560R-CY5

Anti-OSBP2 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-6560R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-6560R-CY5
Codice articolo locale: BOSSBS-6560R-CY5
Descrizione: The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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