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Hai cercato: Cholesterol+margarate


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Codice catalogo: (BOSSBS-2399R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-2399R-A555
Codice articolo locale: BOSSBS-2399R-A555
Descrizione: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2399R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-2399R-A350
Codice articolo locale: BOSSBS-2399R-A350
Descrizione: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5046R-A350)
Fornitore: Bioss
Codice articolo fornitore: BS-5046R-A350
Codice articolo locale: BOSSBS-5046R-A350
Descrizione: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3694R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-3694R-CY5.5
Codice articolo locale: BOSSBS-3694R-CY5.5
Descrizione: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5051R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-5051R-CY3
Codice articolo locale: BOSSBS-5051R-CY3
Descrizione: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5046R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-5046R-A488
Codice articolo locale: BOSSBS-5046R-A488
Descrizione: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5051R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-5051R-FITC
Codice articolo locale: BOSSBS-5051R-FITC
Descrizione: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-5051R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-5051R-HRP
Codice articolo locale: BOSSBS-5051R-HRP
Descrizione: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12324R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-12324R-CY7
Codice articolo locale: BOSSBS-12324R-CY7
Descrizione: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-12324R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-12324R-CY5
Codice articolo locale: BOSSBS-12324R-CY5
Descrizione: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-6764R)
Fornitore: Bioss
Codice articolo fornitore: BS-6764R
Codice articolo locale: BOSSBS-6764R
Descrizione: This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009].
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2399R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-2399R-CY7
Codice articolo locale: BOSSBS-2399R-CY7
Descrizione: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-2399R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-2399R-HRP
Codice articolo locale: BOSSBS-2399R-HRP
Descrizione: Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.
UOM: 1 * 100 µl


Codice catalogo: (BOSSBS-3694R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-3694R-A555
Codice articolo locale: BOSSBS-3694R-A555
Descrizione: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.
UOM: 1 * 100 µl


Fornitore: TCI
Descrizione: Cholesteryl myristate ≥98.0% (by titrimetric analysis)

Codice catalogo: (BOSSBS-5051R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-5051R-CY7
Codice articolo locale: BOSSBS-5051R-CY7
Descrizione: The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain.Cyp46 is also known as 24S-cholesterol hydroxylase.
UOM: 1 * 100 µl


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