Hai cercato: Cholesterol+margarate

Codice catalogo: (BOSSBS-1292R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-1292R-CY7

Codice articolo locale: BOSSBS-1292R-CY7

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BSENG-1784-100)

Fornitore: Biosensis

Codice articolo fornitore: G-1784-100

Codice articolo locale: BSENG-1784-100

Descrizione: Apolipoprotein E (ApoE) is a lipoprotein involved in fat metabolism and acts as cholesterol carrier between cells and across tissues. On a genetic level, three APOE alleles are described, APOE2, APOE3 and APOE4. These alleles give rise to six APOE isoforms, which are differentially implicated in various diseases. In the peripheral system, APOE4 is linked to increased risk of atherosclerosis. In the CNS, the ability of APOE4 in clearing beta-amyloid is impaired, while APOE3 and APOE2 are more efficient in performing this task. The APOE4 genotype in particular has been linked to increased risk for developing Alzheimer's Disease.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-1292R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-1292R-CY5

Codice articolo locale: BOSSBS-1292R-CY5

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI27-622)

Fornitore: ProSci Inc.

Codice articolo fornitore: 27-622

Codice articolo locale: PRSI27-622

Descrizione: NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

UOM: 1 * 50 µG

Promo

Codice catalogo: (PRSI56-934)

Fornitore: ProSci Inc.

Codice articolo fornitore: 56-934

Codice articolo locale: PRSI56-934

Descrizione: This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

UOM: 1 * 400 µl

Promo

Codice catalogo: (PRSI39-859)

Fornitore: ProSci Inc.

Codice articolo fornitore: 39-859

Codice articolo locale: PRSI39-859

Descrizione: Cavin 1-PTRF has been shown to be an essential component of caveolae. Cavin 1-PTRF appear to be recruited to membrane domains containing PS, cholesterol and oligomerized caveolins. Binding of Cavin 1-PTRF to these domains stabilizes the membrane curvature to produce the classic flask shape of caveolae. Disassembly of Cavin 1- PTRF releases caveolar components, including caveolins into the plasma membrane. Succinctly it appears that Cavin 1-PTRF regulates caveola structure and function.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI28-855)

Fornitore: ProSci Inc.

Codice articolo fornitore: 28-855

Codice articolo locale: PRSI28-855

Descrizione: NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

UOM: 1 * 100 µG

Promo

Codice catalogo: (BOSSBS-11736R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-11736R-HRP

Codice articolo locale: BOSSBS-11736R-HRP

Descrizione: NPC2 is a secreted protein mapping against gene 14q24.3 (1,2). NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1,2). Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1,2,3). Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol (3). The disease is caused by HE1 deficiency, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients (3). This differentiates NPC2 from NPC1, as NPC1 has HE1 protein present (3).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1292R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-1292R-A750

Codice articolo locale: BOSSBS-1292R-A750

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localises to the endoplasmic reticulum and catalyses the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1292R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-1292R-A488

Codice articolo locale: BOSSBS-1292R-A488

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1292R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-1292R-CY5.5

Codice articolo locale: BOSSBS-1292R-CY5.5

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

UOM: 1 * 100 µl

Promo

Codice catalogo: (PRSI49-770)

Fornitore: ProSci Inc.

Codice articolo fornitore: 49-770

Codice articolo locale: PRSI49-770

Descrizione: Apolipoprotein D (Apo-D) is a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. It is a glycoprotein of estimated molecular weight 33 kDa. Apo-D is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.

UOM: 1 * 50 µG

Promo

Codice catalogo: (PRSI6265)

Fornitore: ProSci Inc.

Codice articolo fornitore: 6265

Codice articolo locale: PRSI6265

Descrizione: ApoA1 Antibody: Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma, which is correlated with cardiovascular disease. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.

UOM: 1 * 100 µG

Promo

Codice catalogo: (PRSI25-589)

Fornitore: ProSci Inc.

Codice articolo fornitore: 25-589

Codice articolo locale: PRSI25-589

Descrizione: Oxysterols regulate cholesterol homeostasis through the liver X receptor (LXR)- and sterol regulatory element-binding protein (SREBP)-mediated signaling pathways. This gene is an insulin-induced gene. INSIG1 is an endoplasmic reticulum (ER) membrane protein that plays a critical role in regulating cholesterol concentrations in cells. INSIG1 binds to the sterol-sensing domains of SREBP cleavage-activating protein (SCAP) and HMG CoA reductase, and is essential for the sterol-mediated trafficking of the two proteins.The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UOM: 1 * 50 µG

Promo

Codice catalogo: (BOSSBS-8662R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-8662R-CY3

Codice articolo locale: BOSSBS-8662R-CY3

Descrizione: Neuronal axonal membrane protein Nap-22, also designated neuronal tissue-enriched acidic protein or brain acid soluble protein (BASP1), is a Ca2+-dependent calmodulin-binding protein that is important for neuronal sprouting and plasticity. Nap-22 is abundant in brain nerve terminals and is also present in significant amounts in kidney, testis and lymphoid tissue. Nap-22 undergoes N-terminal myristoylation for membrane localization. It has been characterized as a major protein of neuronal rafts, which are known to preferentially bind membranes containing cholesterol. Nap-22 is a crucial protein active in neurite outgrowth and synaptic plasticity.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-8662R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-8662R-FITC

Codice articolo locale: BOSSBS-8662R-FITC

Descrizione: Neuronal axonal membrane protein Nap-22, also designated neuronal tissue-enriched acidic protein or brain acid soluble protein (BASP1), is a Ca2+-dependent calmodulin-binding protein that is important for neuronal sprouting and plasticity. Nap-22 is abundant in brain nerve terminals and is also present in significant amounts in kidney, testis and lymphoid tissue. Nap-22 undergoes N-terminal myristoylation for membrane localization. It has been characterized as a major protein of neuronal rafts, which are known to preferentially bind membranes containing cholesterol. Nap-22 is a crucial protein active in neurite outgrowth and synaptic plasticity.

UOM: 1 * 100 µl

Promo