Hai cercato: Tricarballylic+acid

Descrizione: STOML2 is a 356 amino acid member of the mec-2 family of proteins. Expressed ubiquitously at low levels, STOML2 is highly expressed in heart, liver and pancreas. STOML2 is localized to the cytoplasm with some distribution on the membrane. STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth in samples with different levels of STOML2 indicate that STOML2 could play a role in endometrial tumorigenesis. STOML2 is also thought to play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts.

Codice catalogo: BOSSBS-8861R-A647

UOM: 1 * 100 µl

Codice articolo fornitore: BS-8861R-A647

Codice articolo locale: BOSSBS-8861R-A647

Fornitore: Bioss

Promo

Descrizione: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009].

Codice catalogo: BOSSBS-3472R-FITC

UOM: 1 * 100 µl

Codice articolo fornitore: BS-3472R-FITC

Codice articolo locale: BOSSBS-3472R-FITC

Fornitore: Bioss

Promo

Descrizione: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009].

Codice catalogo: BOSSBS-3472R-A555

UOM: 1 * 100 µl

Codice articolo fornitore: BS-3472R-A555

Codice articolo locale: BOSSBS-3472R-A555

Fornitore: Bioss

Promo

Descrizione: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009].

Codice catalogo: BOSSBS-3472R-A488

UOM: 1 * 100 µl

Codice articolo fornitore: BS-3472R-A488

Codice articolo locale: BOSSBS-3472R-A488

Fornitore: Bioss

Promo

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localises to the endoplasmic reticulum and catalyses the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. Belongs to the cytochrome P450 family.

Codice catalogo: BOSSBS-1292R-A750

UOM: 1 * 100 µl

Codice articolo fornitore: BS-1292R-A750

Codice articolo locale: BOSSBS-1292R-A750

Fornitore: Bioss

Promo

Descrizione: NPC2 is a secreted protein mapping against gene 14q24.3 (1,2). NPC2 regulates the lipid composition of sperm membranes during maturation in the epididymis(1,2). Mutations in the NPC2 gene may cause Nieman-Pick type C2 disease and frontal lobe atrophy (1,2,3). Nieman-Pick type C2 is a fatal hereditary disease characterized by defective lysosome release of cholesterol (3). The disease is caused by HE1 deficiency, a lysosmal protein proven to be undetectable in fibroblasts from NPC2 patients (3). This differentiates NPC2 from NPC1, as NPC1 has HE1 protein present (3).

Codice catalogo: BOSSBS-11736R-HRP

UOM: 1 * 100 µl

Codice articolo fornitore: BS-11736R-HRP

Codice articolo locale: BOSSBS-11736R-HRP

Fornitore: Bioss

Promo

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Codice catalogo: BOSSBS-2443R-A350

UOM: 1 * 100 µl

Codice articolo fornitore: BS-2443R-A350

Codice articolo locale: BOSSBS-2443R-A350

Fornitore: Bioss

Promo

Descrizione: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).

Codice catalogo: BOSSBS-3936R-A750

UOM: 1 * 100 µl

Codice articolo fornitore: BS-3936R-A750

Codice articolo locale: BOSSBS-3936R-A750

Fornitore: Bioss

Promo

Descrizione: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Codice catalogo: BOSSBS-9036R-A350

UOM: 1 * 100 µl

Codice articolo fornitore: BS-9036R-A350

Codice articolo locale: BOSSBS-9036R-A350

Fornitore: Bioss

Promo

Descrizione: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.

Codice catalogo: BOSSBS-9036R-CY5

UOM: 1 * 100 µl

Codice articolo fornitore: BS-9036R-CY5

Codice articolo locale: BOSSBS-9036R-CY5

Fornitore: Bioss

Promo

Descrizione: Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.

Codice catalogo: BOSSBS-3901R-CY7

UOM: 1 * 100 µl

Codice articolo fornitore: BS-3901R-CY7

Codice articolo locale: BOSSBS-3901R-CY7

Fornitore: Bioss

Promo

Descrizione: The apolipoprotein L gene family maps to a region on chromosome 22 and encodes six highly homologous proteins designated apoL-I, apoL-II, apoL-III, apoL-IV, apoL-V and apoL-VI, all of which function as components of plasma lipoproteins. ApoL-IV (apolipoprotein L-IV), also known as APOL4, is a 351 amino acid protein that exists as multiple alternatively spliced isoforms, one of which is secreted. Expressed in spleen, placenta, spinal cord, uterus, testis and trachea, apoL-IV is thought to play a role in lipid exchange and transport throughout the body and may be involved in reverse cholesterol transport, specifically from peripheral cells to the liver. Overexpression of apoL-IV is associated with schizophrenia, suggesting that apoL-IV may play a role in the pathogenesis of neural disorders.

Codice catalogo: BOSSBS-12499R-CY5

UOM: 1 * 100 µl

Codice articolo fornitore: BS-12499R-CY5

Codice articolo locale: BOSSBS-12499R-CY5

Fornitore: Bioss

Promo

Descrizione: Anti-Cholesterol Esterase Rabbit Polyclonal Antibody

Codice catalogo: BIRBORB20952-10

UOM: 1 * 10 mg

Codice articolo fornitore: ORB20952-10

Codice articolo locale: BIRBORB20952-10

Fornitore: Biorbyt

Promo

Descrizione: PG-cholesterylamine was reported by Zhang et al.

Codice catalogo: AATB36700

UOM: 1 * 1 mg

Codice articolo fornitore: 36700

Codice articolo locale: AATB36700

Fornitore: AAT BIOQUEST

Promo

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Codice catalogo: BOSSBS-2443R-A488

UOM: 1 * 100 µl

Codice articolo fornitore: BS-2443R-A488

Codice articolo locale: BOSSBS-2443R-A488

Fornitore: Bioss

Promo

Descrizione: Genetic testing can be used to identify people with a genetic condition which caused them to have an elevated level of cholesterol and which can be fatal. Students can see how genetic testing is carried out and learn about DNA electrophoresis.

Codice catalogo: EDVO118-C

UOM: 1 * 1 pezzi

Codice articolo fornitore: 118-C

Codice articolo locale: EDVO118-C

Fornitore: EDVOTEK

Promo