Hai cercato: Cholesterol+margarate

Codice catalogo: (BOSSBS-11383R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-11383R-A680

Codice articolo locale: BOSSBS-11383R-A680

Descrizione: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

UOM: 1 * 100 µl

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Codice catalogo: (BOSSBS-3900R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-3900R-HRP

Codice articolo locale: BOSSBS-3900R-HRP

Descrizione: CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor.Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. First described in patients who had rickets at a young age despite a history of adequate vitamin D intake. The patients sera had low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D.

UOM: 1 * 100 µl

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Codice catalogo: (BOSSBS-3967R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-3967R-A647

Codice articolo locale: BOSSBS-3967R-A647

Descrizione: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.

UOM: 1 * 100 µl

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Codice catalogo: (BOSSBS-3967R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-3967R-A350

Codice articolo locale: BOSSBS-3967R-A350

Descrizione: PRKAB2 ans PRKAB1 are regulatory subunits of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity.

UOM: 1 * 100 µl

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Codice catalogo: (BOSSBS-2443R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-2443R-CY5

Codice articolo locale: BOSSBS-2443R-CY5

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

UOM: 1 * 100 µl

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Codice catalogo: (BOSSBS-3936R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-3936R-CY7

Codice articolo locale: BOSSBS-3936R-CY7

Descrizione: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9674R)

Fornitore: Bioss

Codice articolo fornitore: BS-9674R

Codice articolo locale: BOSSBS-9674R

Descrizione: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

UOM: 1 * 100 µl

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Codice catalogo: (BOSSBS-9674R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-9674R-CY3

Codice articolo locale: BOSSBS-9674R-CY3

Descrizione: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BIRBORB21044-10)

Fornitore: Biorbyt

Codice articolo fornitore: ORB21044-10

Codice articolo locale: BIRBORB21044-10

Descrizione: Anti-Cholesterol Oxidase Rabbit Polyclonal Antibody

UOM: 1 * 10 mg

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Fornitore: MP Biomedicals

Descrizione: Lipoprotein- cholesterol is a mixture of lipoprotein cholesterol, phospholipids and fatty acids.

Fornitore: MP Biomedicals

Descrizione: Cholesterol is the principal sterol of the higher animals, found in all body tissues. It is the main constituent of gallstones and all biological membranes. Approximately 25% of total brain lipid is cholesterol.

Codice catalogo: (BIRBORB21045-1)

Fornitore: Biorbyt

Codice articolo fornitore: ORB21045-1

Codice articolo locale: BIRBORB21045-1

Descrizione: Anti-Cholesterol Oxidase Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 1 mL

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Codice catalogo: (BOSSBS-10161R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-10161R-A647

Codice articolo locale: BOSSBS-10161R-A647

Descrizione: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-9674R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-9674R-CY5

Codice articolo locale: BOSSBS-9674R-CY5

Descrizione: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BIRBORB20952-10)

Fornitore: Biorbyt

Codice articolo fornitore: ORB20952-10

Codice articolo locale: BIRBORB20952-10

Descrizione: Anti-Cholesterol Esterase Rabbit Polyclonal Antibody

UOM: 1 * 10 mg

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 This is a MarketSource item. Additional charges may apply

Codice catalogo: (BOSSBS-13154R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-13154R-CY7

Codice articolo locale: BOSSBS-13154R-CY7

Descrizione: Adrenodoxin Reductase (ADX Reductase) is a mitochondrial flavoprotein that receives electrons from NADPH and thereby initiates the electron-transport chain serving mitochondrial cytochromes P450. ADX Reductase participates in cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-? hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney and sterol C-27 hydroxylation in the liver. Alternate splicing of ADX Reductase produces two isoforms. Human ADX Reductase maps to human chromosome 17q24-q25.

UOM: 1 * 100 µl

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