Hai cercato: Cholesterol+margarate

Codice catalogo: (BOSSBS-6560R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-6560R-A647

Codice articolo locale: BOSSBS-6560R-A647

Descrizione: The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6560R-A555)

Fornitore: Bioss

Codice articolo fornitore: BS-6560R-A555

Codice articolo locale: BOSSBS-6560R-A555

Descrizione: The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12501R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-12501R-CY3

Codice articolo locale: BOSSBS-12501R-CY3

Descrizione: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12501R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-12501R-A350

Codice articolo locale: BOSSBS-12501R-A350

Descrizione: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11426R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-11426R-FITC

Codice articolo locale: BOSSBS-11426R-FITC

Descrizione: Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11426R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-11426R-HRP

Codice articolo locale: BOSSBS-11426R-HRP

Descrizione: Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3862R-HRP)

Fornitore: Bioss

Codice articolo fornitore: BS-3862R-HRP

Codice articolo locale: BOSSBS-3862R-HRP

Descrizione: SCAP is an escort protein required for cholestrol and lipid homeostasis. Cholesterol homeostasis in animal cells is achieved by regulated cleavage of SREBPs, membrane-bound transcription factors. SCAP forms a complex with SREBPs in order to release the active domains of SREBPs.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6560R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-6560R-A488

Codice articolo locale: BOSSBS-6560R-A488

Descrizione: The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6560R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-6560R-CY5.5

Codice articolo locale: BOSSBS-6560R-CY5.5

Descrizione: The Oxysterol-binding protein (OSBP) family of proteins consist of OSBP (OSBP1) and OSBP2 (ORP-4), which share a high overall similarity. OSBPs are involved in lipid metabolism and signal transduction, as well as vesicle transport, and can translocate to the periphery of Golgi membranes when they are bound to oxysterols. The OSBP protein transports sterols from lysosomes to the nucleus, where sterols downregulate the genes for HMG synthetase, HMG-CoA reductase and the low density lipoprotein receptor (LDLR). OSBP localizes to the cytosol and is widely expressed, while OSBP2 is mainly detected in testis, retina and fetal liver. The extracellular signal-regulated kinase (ERK) signaling pathway is controlled by OSBP via its cholesterol-binding properties. OSBP binds with a high affinity to 25-hydroxy-cholesterol (25-HC), a suppressor of cholesterol synthesis gene transcription in cultured cells.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12501R-FITC)

Fornitore: Bioss

Codice articolo fornitore: BS-12501R-FITC

Codice articolo locale: BOSSBS-12501R-FITC

Descrizione: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11426R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-11426R-A647

Codice articolo locale: BOSSBS-11426R-A647

Descrizione: Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-11426R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-11426R-A488

Codice articolo locale: BOSSBS-11426R-A488

Descrizione: Participates in the synthesis of thyroid hormones. Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3223R)

Fornitore: Bioss

Codice articolo fornitore: BS-3223R

Codice articolo locale: BOSSBS-3223R

Descrizione: HSL/LIPE is found in adipose tissue and heart, where it primarily hydrolyzes stored triglycerides to free fatty acids. It is also found in steroidogenic tissues, where it principally converts cholesteryl esters to free cholesterol for steroid hormone production. There are two named isoforms.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5013R)

Fornitore: Bioss

Codice articolo fornitore: BS-5013R

Codice articolo locale: BOSSBS-5013R

Descrizione: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5013R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-5013R-CY5.5

Codice articolo locale: BOSSBS-5013R-CY5.5

Descrizione: Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-1698R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-1698R-CY7

Codice articolo locale: BOSSBS-1698R-CY7

Descrizione: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.

UOM: 1 * 100 µl

Promo