Hai cercato: Cholesterol+margarate

Codice catalogo: (BOSSBS-1972R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-1972R-A750

Codice articolo locale: BOSSBS-1972R-A750

Descrizione: Central enzyme in the extracellular metabolism of plasma lipoproteins. synthesised mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodelling high-density lipoprotein particles into their spherical forms.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5050R-CY5.5)

Fornitore: Bioss

Codice articolo fornitore: BS-5050R-CY5.5

Codice articolo locale: BOSSBS-5050R-CY5.5

Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5050R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-5050R-A680

Codice articolo locale: BOSSBS-5050R-A680

Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyse many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5050R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-5050R-A647

Codice articolo locale: BOSSBS-5050R-A647

Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12324R-CY3)

Fornitore: Bioss

Codice articolo fornitore: BS-12324R-CY3

Codice articolo locale: BOSSBS-12324R-CY3

Descrizione: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3694R-A647)

Fornitore: Bioss

Codice articolo fornitore: BS-3694R-A647

Codice articolo locale: BOSSBS-3694R-A647

Descrizione: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6480R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-6480R-CY7

Codice articolo locale: BOSSBS-6480R-CY7

Descrizione: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6480R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-6480R-A350

Codice articolo locale: BOSSBS-6480R-A350

Descrizione: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5050R-A488)

Fornitore: Bioss

Codice articolo fornitore: BS-5050R-A488

Codice articolo locale: BOSSBS-5050R-A488

Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5050R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-5050R-A350

Codice articolo locale: BOSSBS-5050R-A350

Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-5050R-CY7)

Fornitore: Bioss

Codice articolo fornitore: BS-5050R-CY7

Codice articolo locale: BOSSBS-5050R-CY7

Descrizione: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-3694R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-3694R-A680

Codice articolo locale: BOSSBS-3694R-A680

Descrizione: High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver. This mechanism, referred to as reverse cholesterol transport, is physiologically important because it maintains systemic cholesterol levels. CETP is responsible for neutral lipid transfer activity in plasma in numerous species. Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention. CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins. In general elevated levels of CETP have been associated with increased risk of coronary heart disease.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6480R-CY5)

Fornitore: Bioss

Codice articolo fornitore: BS-6480R-CY5

Codice articolo locale: BOSSBS-6480R-CY5

Descrizione: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-12324R-A350)

Fornitore: Bioss

Codice articolo fornitore: BS-12324R-A350

Codice articolo locale: BOSSBS-12324R-A350

Descrizione: PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6480R-A680)

Fornitore: Bioss

Codice articolo fornitore: BS-6480R-A680

Codice articolo locale: BOSSBS-6480R-A680

Descrizione: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesising a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

UOM: 1 * 100 µl

Promo

Codice catalogo: (BOSSBS-6480R-A750)

Fornitore: Bioss

Codice articolo fornitore: BS-6480R-A750

Codice articolo locale: BOSSBS-6480R-A750

Descrizione: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. May play an important role in regulating lipid metabolism by synthesising a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

UOM: 1 * 100 µl

Promo