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Image Unavailable-BOSSBS-11190R-A680

Anti-C9a/C9 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Descrizione: C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerization of 12-18 C9 molecules. These polymerized C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
Codice catalogo: BOSSBS-11190R-A680
UOM: 1 * 100 µl
Codice articolo fornitore: BS-11190R-A680
Codice articolo locale: BOSSBS-11190R-A680
Fornitore: Bioss
Image Unavailable-BOSSBS-15307R-FITC

Anti-Complement component C9b Rabbit Polyclonal Antibody (FITC)

Descrizione: C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
Codice catalogo: BOSSBS-15307R-FITC
UOM: 1 * 100 µl
Codice articolo fornitore: BS-15307R-FITC
Codice articolo locale: BOSSBS-15307R-FITC
Fornitore: Bioss
Image Unavailable-BOSSBS-15466R-A680

Anti-Syncytin 2 Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Descrizione: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
Codice catalogo: BOSSBS-15466R-A680
UOM: 1 * 100 µl
Codice articolo fornitore: BS-15466R-A680
Codice articolo locale: BOSSBS-15466R-A680
Fornitore: Bioss
Image Unavailable-BOSSBS-15466R-CY5

Anti-Syncytin 2 Rabbit Polyclonal Antibody (Cy5)

Descrizione: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
Codice catalogo: BOSSBS-15466R-CY5
UOM: 1 * 100 µl
Codice articolo fornitore: BS-15466R-CY5
Codice articolo locale: BOSSBS-15466R-CY5
Fornitore: Bioss
Image Unavailable-BOSSBS-15466R-CY7

Anti-Syncytin 2 Rabbit Polyclonal Antibody (Cy7)

Descrizione: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process. Endogenous envelope proteins may have kept, lost or modified their original function during evolution but this one can still make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein mediates receptor recognition, while the transmembrane protein anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane.
Codice catalogo: BOSSBS-15466R-CY7
UOM: 1 * 100 µl
Codice articolo fornitore: BS-15466R-CY7
Codice articolo locale: BOSSBS-15466R-CY7
Fornitore: Bioss
Image Unavailable-BOSSBS-7744R-CY5

Anti-CHMP4B+CHMP4C Rabbit Polyclonal Antibody (Cy5®)

Descrizione: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
Codice catalogo: BOSSBS-7744R-CY5
UOM: 1 * 100 µl
Codice articolo fornitore: BS-7744R-CY5
Codice articolo locale: BOSSBS-7744R-CY5
Fornitore: Bioss
Image Unavailable-BOSSBS-2945R-A555

Anti-SNX1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Descrizione: Involved in several stages of intracellular trafficking. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:12198132). Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex functions to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable). Can sense membrane curvature and has in vitro vesicle-to-membrane remodeling activity (PubMed:19816406, PubMed:23085988). Involved in retrograde endosome-to-TGN transport of lysosomal enzyme receptors (IGF2R, M6PR and SORT1) and Shiginella dysenteria toxin stxB. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi (PubMed:12198132, PubMed:15498486, PubMed:17550970, PubMed:17101778, PubMed:18088323, PubMed:21040701). Involvement in retromer-independent endocytic trafficking of P2RY1 and lysosomal degradation of protease-activated receptor-1/F2R (PubMed:16407403, PubMed:20070609). Promotes KALRN- and RHOG-dependent but retromer-independent membrane remodeling such as lamellipodium formation; the function is dependent on GEF activity of KALRN (PubMed:20604901). Required for endocytosis of DRD5 upon agonist stimulation but not for basal receptor trafficking (PubMed:23152498).
Codice catalogo: BOSSBS-2945R-A555
UOM: 1 * 100 µl
Codice articolo fornitore: BS-2945R-A555
Codice articolo locale: BOSSBS-2945R-A555
Fornitore: Bioss
Image Unavailable-BOSSBS-13110R-A750

Anti-ETFDH Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Descrizione: Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.
Codice catalogo: BOSSBS-13110R-A750
UOM: 1 * 100 µl
Codice articolo fornitore: BS-13110R-A750
Codice articolo locale: BOSSBS-13110R-A750
Fornitore: Bioss
Image Unavailable-BOSSBS-13110R-A488

Anti-ETFDH Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Descrizione: Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria and processed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia. [provided by RefSeq, Jul 2008].
Codice catalogo: BOSSBS-13110R-A488
UOM: 1 * 100 µl
Codice articolo fornitore: BS-13110R-A488
Codice articolo locale: BOSSBS-13110R-A488
Fornitore: Bioss
Image Unavailable-BOSSBS-6644R

Anti-GPHN Rabbit Polyclonal Antibody

Descrizione: The sub-membraneous region at the postsynaptic membrane contains a number of proteins critical for receptor targeting. Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.
Codice catalogo: BOSSBS-6644R
UOM: 1 * 100 µl
Codice articolo fornitore: BS-6644R
Codice articolo locale: BOSSBS-6644R
Fornitore: Bioss
Product Image-514-4123

Filtri per siringhe, Acrodisc®, Supor®

Descrizione: Acrodisc™ syringe filters with Supor™ membrane deliver high flow rates and low protein binding.
Codice catalogo: 514-4123
UOM: 1 * 75 pezzi
Codice articolo fornitore: 4604
Codice articolo locale: PALL4604
Fornitore: Cytiva (Formerly Pall Lab)

Certificati


Image Unavailable-BOSSBS-1558R-FITC

Anti-Collagen 7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Descrizione: Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
Codice catalogo: BOSSBS-1558R-FITC
UOM: 1 * 100 µl
Codice articolo fornitore: BS-1558R-FITC
Codice articolo locale: BOSSBS-1558R-FITC
Fornitore: Bioss
Image Unavailable-BOSSBS-1558R-HRP

Anti-Collagen 7 Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Descrizione: Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen.
Codice catalogo: BOSSBS-1558R-HRP
UOM: 1 * 100 µl
Codice articolo fornitore: BS-1558R-HRP
Codice articolo locale: BOSSBS-1558R-HRP
Fornitore: Bioss
Image Unavailable-BOSSBS-0319R-A680

Anti-E1 glycoProtein Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Descrizione: Rubella virus (RV), the sole member of the genus Rubivirus within the family Togaviridae, is a small enveloped, positive strand RNA virus. The nucleocapsid consists of 40S genomic RNA and a single species of capsid protein which is enveloped within a host-derived lipid bilayer containing two viral glycoproteins, E1 (58 kDa) and E2 (42-46 kDa). In virus infected cells, RV matures by budding either at the plasma membrane, or at the internal membranes depending on the cell type and enters adjacent uninfected cells by a membrane fusion process in the endosome, directed by E1-E2 heterodimers. The heterodimer formation is crucial for E1 transport out of the endoplasmic reticulum to the Golgi and plasma membrane. In RV E1, a cysteine at position 82 is crucial for the E1-E2 heterodimer formation and cell surface expression of the two proteins. E1 has been shown to be a type 1 membrane protein, rich in cysteine residues with extensive intramolecular disulphide bonds [PMID: 11682134].
Codice catalogo: BOSSBS-0319R-A680
UOM: 1 * 100 µl
Codice articolo fornitore: BS-0319R-A680
Codice articolo locale: BOSSBS-0319R-A680
Fornitore: Bioss
Image Unavailable-BOSSBS-11352R-FITC

Anti-MAGI1/IRSP58 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Descrizione: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
Codice catalogo: BOSSBS-11352R-FITC
UOM: 1 * 100 µl
Codice articolo fornitore: BS-11352R-FITC
Codice articolo locale: BOSSBS-11352R-FITC
Fornitore: Bioss
Image Unavailable-BOSSBS-11352R-A555

Anti-MAGI1/IRSP58 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Descrizione: The membrane-associated guanylate kinase (MAGUK) proteins are concentrated at the membrane-cytoskeletal interface where they facilitate the assembly of multiprotein complexes on the inner surface of the plasma membrane. Three protein-protein interaction modules characteristically define MAGUK related proteins: the PDZ domain, the SH3 domain and the guanylate kinase (GuK) domain. The closely related MAGUK proteins, MAGI-1, MAGI-2 and MAGI-3 (membrane associated guanylate kinase inverted-1 and 2), likewise contain the GuK domain and five PDZ domains; however, the SH3 domain is replaced with a WW domain. The transcripts of MAGI-1 are alternatively spliced to produce three distinct proteins having unique C-terminals. Two variants, MAGI-1a and MAGI-1b, are associated with the membrane and cytosolic fractions and are primarily expressed in the brain. The third isoform, MAGI-1c, encodes for a nuclear localization signal that localizes MAGI-1c to the nucleus, and it is primarily expressed in the liver and kidney. MAGI-2 and MAGI-3 are localized to the plasma membrane, and they contribute to protein scaffolding by associating with the protein phosphatase PTEN.
Codice catalogo: BOSSBS-11352R-A555
UOM: 1 * 100 µl
Codice articolo fornitore: BS-11352R-A555
Codice articolo locale: BOSSBS-11352R-A555
Fornitore: Bioss
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