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Image Unavailable-BOSSBS-0177R-A488

Anti-AGER Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-0177R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-0177R-A488
Codice articolo locale: BOSSBS-0177R-A488
Descrizione: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S1A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides (By similarity). Interaction with S1B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3872R-CY5.5

Anti-GATA1 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-3872R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-3872R-CY5.5
Codice articolo locale: BOSSBS-3872R-CY5.5
Descrizione: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1469R-A750

Anti-GRP75 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-1469R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-1469R-A750
Codice articolo locale: BOSSBS-1469R-A750
Descrizione: Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3872R-A750

Anti-GATA-1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Codice catalogo: (BOSSBS-3872R-A750)
Fornitore: Bioss
Codice articolo fornitore: BS-3872R-A750
Codice articolo locale: BOSSBS-3872R-A750
Descrizione: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4890R-CY5

Anti-CD24 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-4890R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-4890R-CY5
Codice articolo locale: BOSSBS-4890R-CY5
Descrizione: Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11348R-CY5

Anti-HPCA Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-11348R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-11348R-CY5
Codice articolo locale: BOSSBS-11348R-CY5
Descrizione: Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11348R-CY7

Anti-HPCA Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-11348R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-11348R-CY7
Codice articolo locale: BOSSBS-11348R-CY7
Descrizione: Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11833R-A555

Anti-DAGLA Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-11833R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-11833R-A555
Codice articolo locale: BOSSBS-11833R-A555
Descrizione: Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4999R-CY3

Anti-AGER Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-4999R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-4999R-CY3
Codice articolo locale: BOSSBS-4999R-CY3
Descrizione: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4999R-CY5

Anti-AGER Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-4999R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-4999R-CY5
Codice articolo locale: BOSSBS-4999R-CY5
Descrizione: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4999R-CY5.5

Anti-AGER Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-4999R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-4999R-CY5.5
Codice articolo locale: BOSSBS-4999R-CY5.5
Descrizione: Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Interaction with S100B after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity). Receptor for amyloid beta peptide. Contributes to the translocation of amyloid-beta peptide (ABPP) across the cell membrane from the extracellular to the intracellular space in cortical neurons. ABPP-initiated RAGE signaling, especially stimulation of p38 mitogen-activated protein kinase (MAPK), has the capacity to drive a transport system delivering ABPP as a complex with RAGE to the intraneuronal space. Can also bind oligonucleotides.
UOM: 1 * 100 µl
Product Image-SCOT286044209

Retaining devices, complete, for stopcock keys, DURAN®

Fornitore: DWK Life Sciences
Descrizione: PP, three parts.

Image Unavailable-BOSSBS-3872R-A555

Anti-GATA1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Codice catalogo: (BOSSBS-3872R-A555)
Fornitore: Bioss
Codice articolo fornitore: BS-3872R-A555
Codice articolo locale: BOSSBS-3872R-A555
Descrizione: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3872R-CY3

Anti-GATA1 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-3872R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-3872R-CY3
Codice articolo locale: BOSSBS-3872R-CY3
Descrizione: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3872R-FITC

Anti-GATA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-3872R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-3872R-FITC
Codice articolo locale: BOSSBS-3872R-FITC
Descrizione: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5890R-A647

Anti-LUM Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-5890R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-5890R-A647
Codice articolo locale: BOSSBS-5890R-A647
Descrizione: Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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