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Image Unavailable-BOSSBS-3541R-CY5

Anti-PIN1 Rabbit Polyclonal Antibody (Cy5®)

Codice catalogo: (BOSSBS-3541R-CY5)
Fornitore: Bioss
Codice articolo fornitore: BS-3541R-CY5
Codice articolo locale: BOSSBS-3541R-CY5
Descrizione: Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11348R-CY3

Anti-HPCA Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-11348R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-11348R-CY3
Codice articolo locale: BOSSBS-11348R-CY3
Descrizione: Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3541R-CY7

Anti-PIN1 Rabbit Polyclonal Antibody (Cy7®)

Codice catalogo: (BOSSBS-3541R-CY7)
Fornitore: Bioss
Codice articolo fornitore: BS-3541R-CY7
Codice articolo locale: BOSSBS-3541R-CY7
Descrizione: Pin1 is a Peptidyl-prolyl isomerases (PPIase). Peptidyl-prolyl isomerases (PPIase) facilitate the cis-trans interconversion of the peptidyl-prolyl bond thereby affecting protein folding. Pin1 is a PPIase which specifically recognizes phosphorylated S/T-P bonds. Pin1 has been implicated in tau pathologies that underlie Alzheimer's Disease. Pin1 binds to tau phosphorylated specifically on the Thr231-Pro site and induces conformational changes in tau. Such conformational changes can directly restore the ability of phosphorylated Tau to bind microtubules and promote microtubule assembly and/or facilitate tau dephosphorylation. Pin1 expression inversely correlates with the predicted neuronal vulnerability in normally aged brain and also with actual neurofibrillary degeneration in AD brain. Pin1 could be pivotal for maintainance of normal neuronal function and preventing age-dependent neurodegeneration.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10283R-A488

Anti-PHB2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Codice catalogo: (BOSSBS-10283R-A488)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-A488
Codice articolo locale: BOSSBS-10283R-A488
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-10283R-A647

Anti-PHB2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Codice catalogo: (BOSSBS-10283R-A647)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-A647
Codice articolo locale: BOSSBS-10283R-A647
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0519R-CY3

Anti-ATF3 Rabbit Polyclonal Antibody (Cy3®)

Codice catalogo: (BOSSBS-0519R-CY3)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-CY3
Codice articolo locale: BOSSBS-0519R-CY3
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl
Product Image-515-0116

Capsule di filtrazione a flusso tangenziale, Minimate™

Fornitore: Cytiva (Formerly Pall Lab)
Descrizione: The disposable Minimate™ TFF capsules, with Omega™ membrane, can perform concentration processes desalting or buffer exchange on the same system with minimal user intervention, and achieves high concentration factors in a single step due to the low hold-up volume of the devices.

Image Unavailable-BOSSBS-0519R-FITC

Anti-ATF3 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-0519R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-FITC
Codice articolo locale: BOSSBS-0519R-FITC
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0519R-CY5.5

Anti-ATF3 Rabbit Polyclonal Antibody (Cy5.5®)

Codice catalogo: (BOSSBS-0519R-CY5.5)
Fornitore: Bioss
Codice articolo fornitore: BS-0519R-CY5.5
Codice articolo locale: BOSSBS-0519R-CY5.5
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1449R-HRP

Anti-Prohibitin Rabbit Polyclonal Antibody (HRP (Horseradish PE (Phycoerythrin)rOxidase))

Codice catalogo: (BOSSBS-1449R-HRP)
Fornitore: Bioss
Codice articolo fornitore: BS-1449R-HRP
Codice articolo locale: BOSSBS-1449R-HRP
Descrizione: Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Product Image-630-1330

Staffe di montaggio

Fornitore: SCHOTT AG Lighting and imaging
Descrizione: Brackets, Staffa per fissaggio alla base come unità autonoma

Product Image-630-3502

Power supplies

Fornitore: SCHOTT AG Lighting and imaging
Descrizione: Power supply, Cavo di alimentazione EU, 1,8 m

Product Image-631-0896

Accessories for LED cold light sources

Fornitore: SCHOTT AG Lighting and imaging
Descrizione: Adattatore TLS Ø = 84 per piastra di base Ø 100 mm

Product Image-631-1033

Accessories for illumination systems and light source

Fornitore: SCHOTT AG Lighting and imaging
Descrizione: Illuminatori a luce fredda, Supporto per lente focalizzatrice (631-0009)

Image Unavailable-BOSSBS-10283R-FITC

Anti-PHB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Codice catalogo: (BOSSBS-10283R-FITC)
Fornitore: Bioss
Codice articolo fornitore: BS-10283R-FITC
Codice articolo locale: BOSSBS-10283R-FITC
Descrizione: Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
UOM: 1 * 100 µl
Product Image-BOSSBS-0517R

Anti-ATF1 Rabbit Polyclonal Antibody

Codice catalogo: (BOSSBS-0517R)
Fornitore: Bioss
Codice articolo fornitore: BS-0517R
Codice articolo locale: BOSSBS-0517R
Descrizione: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
UOM: 1 * 100 µl
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La disponibilità per questo articolo è limitata, ma potrebbe essere disponibile in un magazzino vicino a voi. Si prega di assicurarsi che si è effettuato l'accesso al sito, in modo che ledisponibilità possano essere visualizzati. Se il call è ancora visualizzato e hai bisogno di assistenza, si prega di telefonare a 1-800-932 - 5000.
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